Best TWAS P=6.7e-10 · Best GWAS P=9.36e-10 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | The Cancer Genome Atlas | Lung Adenocarcinoma | CADM2 | 0.08 | 0.04 | lasso | 4 | 0.05 | 2.1e-06 | 6.0 | 6.2 | 6.7e-10 | 0.96 | 0.02 | 0.98 | TRUE |
| 2 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | CADM2 | 0.05 | 0.03 | lasso | 3 | 0.04 | 5.0e-05 | 6.0 | 6.1 | 1.1e-09 | 0.97 | 0.02 | 0.98 | FALSE |
| 3 | The Cancer Genome Atlas | Thyroid Carcinoma | CADM2 | 0.05 | 0.00 | blup | 339 | 0.02 | 3.2e-03 | 1.9 | 5.3 | 1.1e-07 | 0.66 | 0.04 | 0.61 | FALSE |