Best TWAS P=1.9e-08 · Best GWAS P=1.19e-06 conditioned to 0.0112
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Aorta | UVSSA | 0.33 | 0.06 | enet | 30 | 0.28 | 7.2e-16 | -3.1 | -5.3 | 1.1e-07 | 0.56 | 0.01 | 0.96 | FALSE |
| 2 | GTEx | Artery Tibial | CRIPAK | 0.42 | 0.09 | enet | 50 | 0.34 | 1.3e-27 | 2.2 | -5.2 | 2.2e-07 | 0.37 | 0.18 | 0.04 | FALSE |
| 3 | GTEx | Breast Mammary Tissue (Female) | UVSSA | 0.21 | 0.02 | enet | 24 | 0.05 | 1.3e-02 | -3.1 | -5.4 | 6.5e-08 | 0.49 | 0.01 | 0.15 | FALSE |
| 4 | GTEx | Muscle Skeletal | CRIPAK | 0.25 | 0.11 | enet | 32 | 0.18 | 7.6e-18 | -3.6 | -5.4 | 5.2e-08 | 0.52 | 0.11 | 0.38 | FALSE |
| 5 | GTEx | Nerve Tibial | CRIPAK | 0.50 | 0.11 | enet | 76 | 0.38 | 1.1e-28 | -3.2 | -5.6 | 1.9e-08 | 0.46 | 0.16 | 0.13 | TRUE |
| 6 | GTEx | Skin Sun Exposed Lower leg | CRIPAK | 0.36 | 0.09 | enet | 40 | 0.35 | 8.7e-30 | -3.1 | -5.4 | 6.4e-08 | 0.46 | 0.14 | 0.20 | FALSE |