[Hub]/) : Traits : Hand grip strength (left) : ← →

chr4:17,104,059-18,507,692

Best TWAS P=5.22e-17 · Best GWAS P=4.92e-19 conditioned to 0.000187

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
2	GTEx	Artery Aorta	DCAF16	0.10	0.01	enet	6	0.02	4.7e-02	-8.1	8.4	5.2e-17	-0.79	0.10	0.58	TRUE
5	GTEx	Breast Mammary Tissue (Male)	DCAF16	0.24	0.03	enet	18	-0.01	4.4e-01	-7.8	8.2	2.2e-16	-0.75	0.03	0.68	FALSE
17	The Cancer Genome Atlas	Brain Lower Grade Glioma	NCAPG	0.02	0.03	lasso	1	0.02	9.0e-04	-7.9	-7.9	2.1e-15	0.86	0.01	0.84	FALSE
16	The Cancer Genome Atlas	Brain Lower Grade Glioma	DCAF16	0.09	0.02	lasso	3	0.04	5.2e-05	4.8	7.7	1.1e-14	-0.63	0.04	0.90	FALSE
15	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	NCAPG	0.14	0.07	lasso	3	0.07	5.2e-08	-7.9	-7.7	1.4e-14	0.83	0.01	0.99	FALSE
10	GTEx	Spleen	DCAF16	0.35	0.02	lasso	5	0.11	8.5e-04	4.7	7.7	1.5e-14	-0.65	0.04	0.66	FALSE
21	The Cancer Genome Atlas	Thyroid Carcinoma	DCAF16	0.07	0.04	blup	31	0.07	4.9e-07	4.9	7.5	5.2e-14	-0.64	0.15	0.77	FALSE
12	GTEx	Thyroid	DCAF16	0.11	0.02	lasso	5	0.03	2.3e-03	4.7	7.3	2.1e-13	-0.53	0.21	0.64	FALSE
13	ROSMAP	Brain Pre-frontal Cortex	DCAF16	0.04	0.02	bslmm	379	0.01	3.9e-02	-7.9	7.3	2.4e-13	-0.83	0.03	0.88	FALSE
14	The Cancer Genome Atlas	Colon Adenocarcinoma	NCAPG	0.08	0.04	blup	34	0.09	1.1e-05	-7.9	-7.0	2.3e-12	0.82	0.01	0.99	FALSE
4	GTEx	Breast Mammary Tissue	DCAF16	0.12	0.08	lasso	4	0.10	6.4e-06	4.9	7.0	3.7e-12	-0.51	0.10	0.77	FALSE
19	The Cancer Genome Atlas	Prostate Adenocarcinoma	DCAF16	0.04	0.04	blup	31	0.04	2.2e-05	4.7	6.7	1.9e-11	-0.56	0.26	0.26	FALSE
20	The Cancer Genome Atlas	Prostate Adenocarcinoma	NCAPG	0.02	0.02	blup	34	0.02	3.4e-03	-6.7	-6.3	2.3e-10	0.75	0.03	0.48	FALSE
18	The Cancer Genome Atlas	Lung Adenocarcinoma	NCAPG	0.06	0.02	blup	34	0.04	1.0e-05	-7.9	-6.2	6.8e-10	0.67	0.01	0.90	FALSE
3	GTEx	Artery Tibial	DCAF16	0.16	0.16	lasso	5	0.13	1.5e-10	4.8	5.7	1.0e-08	-0.35	1.00	0.00	FALSE
7	GTEx	Nerve Tibial	DCAF16	0.16	0.14	lasso	3	0.14	2.8e-10	4.7	5.7	1.2e-08	-0.35	0.99	0.00	FALSE
11	GTEx	Stomach	DCAF16	0.21	0.04	lasso	6	0.02	5.6e-02	4.9	5.6	2.2e-08	-0.25	0.19	0.05	FALSE
9	GTEx	Skin Not Sun Exposed Suprapubic	DCAF16	0.16	0.08	lasso	5	0.12	4.4e-07	4.9	5.5	3.4e-08	-0.34	0.63	0.05	FALSE
8	GTEx	Pituitary	DCAF16	0.27	0.20	enet	15	0.19	1.3e-05	4.7	5.4	7.1e-08	-0.37	0.08	0.21	FALSE
6	GTEx	Esophagus Mucosa	DCAF16	0.10	0.02	lasso	4	0.02	8.3e-03	4.9	5.4	8.3e-08	-0.35	0.14	0.35	FALSE
1	GTEx	Adipose Visceral Omentum	DCAF16	0.19	0.06	enet	10	0.11	3.9e-06	4.7	5.3	1.3e-07	-0.34	0.38	0.29	FALSE