TWAS
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Models
Genes
Traits
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Traits
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Hand grip strength (left)
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chr16:19,022,448-20,423,000
Best TWAS P=1.1e-07 · Best GWAS P=4.61e-07 conditioned to 0.00012
19M
19.2M
19.4M
19.6M
19.8M
20M
20.2M
20.4M
0
1
2
3
4
5
6
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
3
GTEx
Esophagus Gastroesophageal Junction
AC002550.5
0.62
0.54
enet
35
0.63
4.4e-29
-4.6
-5.3
1.1e-07
-0.25
0.05
0.92
TRUE
1
GTEx
Colon Transverse
KNOP1
0.22
0.23
enet
19
0.24
9.8e-12
-4.5
-5.2
2.2e-07
-0.25
0.06
0.92
FALSE
2
GTEx
Esophagus Gastroesophageal Junction
KNOP1
0.51
0.44
enet
22
0.56
5.3e-24
-4.3
-5.1
2.8e-07
-0.26
0.07
0.90
FALSE