Best TWAS P=1.14e-07 · Best GWAS P=2.85e-07 conditioned to 0.385
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Tibial | ZNF500 | 0.19 | 0.18 | lasso | 5 | 0.17 | 1.8e-13 | 5.0 | 5.2 | 2.0e-07 | 0.94 | 0.01 | 0.99 | FALSE |
| 2 | GTEx | Stomach | MGRN1 | 0.34 | 0.18 | enet | 14 | 0.22 | 1.2e-10 | 4.5 | -5.2 | 2.4e-07 | -0.77 | 0.11 | 0.86 | FALSE |
| 3 | The Cancer Genome Atlas | Breast Invasive Carcinoma | C16orf71 | 0.01 | 0.01 | blup | 52 | 0.01 | 3.1e-03 | 5.0 | 5.3 | 1.1e-07 | 0.89 | 0.01 | 0.92 | TRUE |
| 4 | The Cancer Genome Atlas | Rectum Adenocarcinoma | C16orf71 | 0.22 | 0.17 | enet | 10 | 0.21 | 9.9e-06 | 4.4 | 5.3 | 1.2e-07 | 0.81 | 0.03 | 0.84 | FALSE |