[Hub]/) : Traits : Hand grip strength (left) :

chr2:43,417,083-44,920,960

Best TWAS P=4.63e-09 · Best GWAS P=1.99e-10 conditioned to 0.0131

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Brain Cerebellar Hemisphere LRPPRC 0.34 0.15 enet 13 0.10 1.5e-03 -6.4 5.5 5.0e-08 -0.80 0.02 0.90 FALSE
2 GTEx Brain Cortex LRPPRC 0.17 0.10 lasso 3 0.11 4.9e-04 5.1 5.9 4.6e-09 -0.91 0.03 0.84 TRUE
3 GTEx Nerve Tibial LRPPRC 0.25 0.07 lasso 6 0.04 6.4e-04 5.1 5.6 2.2e-08 -0.84 0.06 0.94 FALSE
4 GTEx Testis LRPPRC 0.30 0.20 enet 16 0.19 5.3e-09 5.3 5.2 2.3e-07 -0.79 0.58 0.42 FALSE
5 The Cancer Genome Atlas Cervical Squamous Cell Carcinoma LRPPRC 0.06 0.04 lasso 2 0.05 2.8e-03 5.3 5.3 1.3e-07 -0.80 0.06 0.33 FALSE
6 The Cancer Genome Atlas Lung Adenocarcinoma LRPPRC 0.09 0.11 lasso 3 0.10 5.6e-12 5.2 5.2 2.2e-07 -0.79 0.82 0.18 FALSE
7 The Cancer Genome Atlas Rectum Adenocarcinoma LRPPRC 0.27 0.12 blup 109 0.13 7.3e-04 4.3 5.5 3.0e-08 -0.80 0.09 0.59 FALSE
8 The Cancer Genome Atlas Testicular Germ Cell Tumors LRPPRC 0.17 0.14 lasso 6 0.13 2.3e-05 5.2 5.1 2.8e-07 -0.76 0.44 0.51 FALSE