[Hub]/) : Traits : Hand grip strength (left) : ← →

chr2:23,604,114-25,889,403

Best TWAS P=4.48e-15 · Best GWAS P=2.29e-14 conditioned to NaN

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
16	ROSMAP	Brain Pre-frontal Cortex	ADCY3	0.17	0.26	enet	32	0.26	6.8e-33	-7.43	7.8	4.5e-15	-0.43	0.03	0.97	TRUE
12	GTEx	Nerve Tibial	RP11-443B20.1	0.07	0.03	enet	6	0.02	1.1e-02	-6.55	7.5	5.9e-14	-0.44	0.06	0.91	TRUE
8	GTEx	Cells EBV-transformed lymphocytes	RP11-443B20.1	0.13	0.13	enet	9	0.05	9.2e-03	-7.17	7.2	5.4e-13	-0.38	0.07	0.80	TRUE
13	GTEx	Whole Blood	DNAJC27	0.08	0.10	lasso	1	0.10	2.2e-09	-7.15	-7.2	8.9e-13	0.41	0.08	0.92	TRUE
10	GTEx	Lung	NCOA1	0.12	0.04	lasso	7	0.06	1.9e-05	-3.02	-7.0	2.9e-12	0.64	0.04	0.93	TRUE
1	CommonMind	Brain Pre-frontal Cortex	ADCY3	0.16	0.12	lasso	10	0.14	3.2e-17	-6.61	6.7	1.6e-11	-0.40	0.23	0.77	TRUE
17	The Cancer Genome Atlas	Breast Invasive Carcinoma	ADCY3	0.05	0.03	blup	81	0.03	5.0e-07	-2.84	6.1	1.3e-09	-0.70	0.37	0.60	TRUE
9	GTEx	Esophagus Mucosa	TP53I3	0.16	0.03	enet	23	0.06	8.2e-05	0.75	-5.2	2.6e-07	0.18	0.02	0.23	TRUE
14	GTEx	Whole Blood	ADCY3	0.23	0.24	enet	24	0.27	5.5e-25	-7.43	-7.8	5.2e-15	0.45	0.04	0.96	FALSE
11	GTEx	Nerve Tibial	ADCY3	0.09	0.05	enet	6	0.03	2.2e-03	-6.55	7.6	2.8e-14	-0.42	0.05	0.94	FALSE
15	GTEx	Whole Blood	RP11-443B20.1	0.21	0.17	enet	32	0.20	1.8e-18	-7.15	-7.6	3.0e-14	0.42	0.05	0.95	FALSE
5	GTEx	Artery Tibial	ADCY3	0.21	0.14	lasso	6	0.15	4.3e-12	-6.55	-7.3	2.9e-13	0.51	0.18	0.82	FALSE
2	CommonMind	Brain Pre-frontal Cortex	CENPO	0.07	0.03	bslmm	322	0.03	7.0e-05	-4.54	7.1	1.0e-12	-0.71	0.05	0.92	FALSE
7	GTEx	Cells EBV-transformed lymphocytes	ADCY3	0.25	0.23	enet	10	0.12	9.2e-05	-7.17	7.0	2.4e-12	-0.38	0.11	0.86	FALSE
18	The Cancer Genome Atlas	Brain Lower Grade Glioma	ADCY3	0.03	0.02	blup	81	0.02	7.1e-04	-5.02	6.4	1.5e-10	-0.33	0.08	0.84	FALSE
3	GTEx	Adipose Subcutaneous	ADCY3	0.07	0.04	lasso	6	0.01	3.2e-02	-7.17	-6.1	1.0e-09	0.34	0.05	0.94	FALSE
6	GTEx	Artery Tibial	RP11-443B20.1	0.17	0.08	enet	40	0.09	8.2e-08	-6.55	-5.9	3.3e-09	0.47	0.08	0.91	FALSE
4	GTEx	Adrenal Gland	PTRHD1	0.32	0.28	lasso	3	0.26	8.3e-10	5.02	-5.2	2.5e-07	0.33	0.98	0.01	FALSE