Best TWAS P=2.87e-08 · Best GWAS P=8.7e-07 conditioned to 0.724
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adrenal Gland | MYLK4 | 0.38 | 0.28 | lasso | 2 | 0.27 | 3.0e-10 | -4.9 | -5.2 | 2.2e-07 | 0.96 | 0 | 1.00 | FALSE |
| 2 | GTEx | Esophagus Mucosa | MYLK4 | 0.27 | 0.26 | lasso | 2 | 0.29 | 1.1e-19 | -4.9 | -5.2 | 2.3e-07 | 0.96 | 0 | 1.00 | FALSE |
| 3 | GTEx | Spleen | MYLK4 | 0.61 | 0.10 | lasso | 19 | 0.08 | 4.3e-03 | -4.9 | -5.2 | 2.4e-07 | 0.85 | 0 | 0.81 | FALSE |
| 4 | GTEx | Thyroid | MYLK4 | 0.45 | 0.29 | enet | 43 | 0.31 | 2.4e-24 | -4.9 | -5.5 | 2.9e-08 | 0.85 | 0 | 1.00 | TRUE |