[Hub]/) : Traits : Hand grip strength (right) :

chr11:76,537,114-78,216,992

Best TWAS P=1.24e-13 · Best GWAS P=2.83e-11 conditioned to 0.0201

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex AQP11 0.14 0.11 lasso 7 0.13 1.0e-15 -4.0 -6.2 7.5e-10 -0.59 0.98 0.02 FALSE
2 GTEx Artery Aorta CLNS1A 0.11 0.01 enet 25 0.03 7.4e-03 6.3 -5.2 2.6e-07 -0.49 0.05 0.88 FALSE
3 GTEx Artery Tibial AP000580.1 0.12 0.08 lasso 7 0.09 1.1e-07 5.2 -5.9 3.4e-09 -0.78 0.05 0.95 FALSE
4 GTEx Breast Mammary Tissue (Male) AP000580.1 0.31 0.04 lasso 4 0.09 3.6e-03 -5.7 -6.8 1.0e-11 -0.49 0.05 0.36 FALSE
5 GTEx Cells Transformed fibroblasts AP000580.1 0.12 0.02 enet 18 0.08 1.1e-06 6.3 -6.0 2.5e-09 -0.56 0.02 0.98 FALSE
6 GTEx Skin Sun Exposed Lower leg AP000580.1 0.09 0.09 lasso 4 0.07 1.1e-06 6.3 -6.3 3.8e-10 -0.74 0.02 0.98 FALSE
7 GTEx Thyroid AP000580.1 0.08 0.04 lasso 3 0.05 1.2e-04 6.3 -6.4 1.7e-10 -0.79 0.03 0.92 FALSE
8 ROSMAP Brain Pre-frontal Cortex AQP11 0.07 0.02 blup 320 0.05 1.5e-06 6.3 -7.4 1.2e-13 -0.66 0.01 0.99 TRUE
9 YFS Blood AQP11 0.01 0.02 lasso 2 0.02 2.0e-06 -5.8 -5.8 6.2e-09 -0.45 0.29 0.71 FALSE
10 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma AQP11 0.04 0.01 blup 39 0.02 9.1e-04 -2.6 -5.4 8.6e-08 -0.44 0.12 0.30 FALSE
11 The Cancer Genome Atlas Brain Lower Grade Glioma AQP11 0.07 0.01 blup 39 0.03 9.7e-05 -5.8 -7.1 1.8e-12 -0.69 0.03 0.84 FALSE
12 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma AQP11 0.04 0.04 lasso 1 0.02 9.5e-03 -5.8 -5.8 6.4e-09 -0.45 0.04 0.20 FALSE
13 The Cancer Genome Atlas Pancreatic Adenocarcinoma C11orf67 0.08 0.09 lasso 9 0.07 1.0e-03 -6.2 6.1 1.4e-09 0.43 0.02 0.75 FALSE
14 The Cancer Genome Atlas Testicular Germ Cell Tumors AQP11 0.11 0.04 lasso 3 0.06 3.3e-03 -5.8 -5.6 2.0e-08 -0.42 0.06 0.28 FALSE