[Hub]/) : Traits : Hand grip strength (right) : ← →

chr11:76,537,114-78,216,992

Best TWAS P=1.24e-13 · Best GWAS P=2.83e-11 conditioned to 0.0201

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
8	ROSMAP	Brain Pre-frontal Cortex	AQP11	0.07	0.02	blup	320	0.05	1.5e-06	6.3	-7.4	1.2e-13	-0.66	0.01	0.99	TRUE
11	The Cancer Genome Atlas	Brain Lower Grade Glioma	AQP11	0.07	0.01	blup	39	0.03	9.7e-05	-5.8	-7.1	1.8e-12	-0.69	0.03	0.84	FALSE
4	GTEx	Breast Mammary Tissue (Male)	AP000580.1	0.31	0.04	lasso	4	0.09	3.6e-03	-5.7	-6.8	1.0e-11	-0.49	0.05	0.36	FALSE
7	GTEx	Thyroid	AP000580.1	0.08	0.04	lasso	3	0.05	1.2e-04	6.3	-6.4	1.7e-10	-0.79	0.03	0.92	FALSE
6	GTEx	Skin Sun Exposed Lower leg	AP000580.1	0.09	0.09	lasso	4	0.07	1.1e-06	6.3	-6.3	3.8e-10	-0.74	0.02	0.98	FALSE
1	CommonMind	Brain Pre-frontal Cortex	AQP11	0.14	0.11	lasso	7	0.13	1.0e-15	-4.0	-6.2	7.5e-10	-0.59	0.98	0.02	FALSE
13	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	C11orf67	0.08	0.09	lasso	9	0.07	1.0e-03	-6.2	6.1	1.4e-09	0.43	0.02	0.75	FALSE
5	GTEx	Cells Transformed fibroblasts	AP000580.1	0.12	0.02	enet	18	0.08	1.1e-06	6.3	-6.0	2.5e-09	-0.56	0.02	0.98	FALSE
3	GTEx	Artery Tibial	AP000580.1	0.12	0.08	lasso	7	0.09	1.1e-07	5.2	-5.9	3.4e-09	-0.78	0.05	0.95	FALSE
9	YFS	Blood	AQP11	0.01	0.02	lasso	2	0.02	2.0e-06	-5.8	-5.8	6.2e-09	-0.45	0.29	0.71	FALSE
12	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	AQP11	0.04	0.04	lasso	1	0.02	9.5e-03	-5.8	-5.8	6.4e-09	-0.45	0.04	0.20	FALSE
14	The Cancer Genome Atlas	Testicular Germ Cell Tumors	AQP11	0.11	0.04	lasso	3	0.06	3.3e-03	-5.8	-5.6	2.0e-08	-0.42	0.06	0.28	FALSE
10	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	AQP11	0.04	0.01	blup	39	0.02	9.1e-04	-2.6	-5.4	8.6e-08	-0.44	0.12	0.30	FALSE
2	GTEx	Artery Aorta	CLNS1A	0.11	0.01	enet	25	0.03	7.4e-03	6.3	-5.2	2.6e-07	-0.49	0.05	0.88	FALSE