[Hub]/) : Traits : Hand grip strength (right) : ← →

chr11:73,024,914-75,075,866

Best TWAS P=1.3e-20 · Best GWAS P=4.73e-22 conditioned to 0.704

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
4	The Cancer Genome Atlas	Breast Invasive Carcinoma	POLD3	0.02	0.01	lasso	3	0.01	0.0018	8.3	-9.3	1.3e-20	-0.65	0.08	0.18	TRUE
2	GTEx	Testis	POLD3	0.18	-0.01	enet	48	0.00	0.2900	2.4	-7.1	1.5e-12	-0.58	0.02	0.72	TRUE
3	ROSMAP	Brain Pre-frontal Cortex	C2CD3	0.04	0.01	blup	446	0.02	0.0021	2.2	5.7	9.0e-09	0.33	0.21	0.26	TRUE
1	GTEx	Cells Transformed fibroblasts	AP001372.2	0.10	0.02	enet	13	0.05	0.0002	-1.8	6.9	6.5e-12	0.48	0.13	0.35	FALSE
5	The Cancer Genome Atlas	Thyroid Carcinoma	POLD3	0.03	0.00	blup	77	0.01	0.0133	8.5	-6.4	2.0e-10	-0.32	0.04	0.07	FALSE