Best TWAS P=1e-12 · Best GWAS P=2.23e-13 conditioned to 2.82e-07
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Skin Sun Exposed Lower leg | LOXL1-AS1 | 0.11 | 0.05 | enet | 11 | 0.10 | 7.3e-09 | 1.7 | 5.2 | 1.6e-07 | -0.41 | 0.82 | 0.09 | FALSE |
| 2 | GTEx | Testis | LOXL1-AS1 | 0.36 | 0.15 | lasso | 10 | 0.13 | 2.4e-06 | -6.2 | -6.3 | 4.0e-10 | 0.58 | 0.42 | 0.23 | FALSE |
| 3 | GTEx | Thyroid | LOXL1-AS1 | 0.15 | 0.03 | enet | 40 | 0.03 | 2.6e-03 | -6.2 | 7.1 | 1.0e-12 | -0.33 | 0.11 | 0.27 | TRUE |
| 4 | GTEx | Whole Blood | LOXL1-AS1 | 0.10 | 0.00 | enet | 33 | 0.00 | 5.8e-01 | 6.4 | 6.0 | 2.2e-09 | -0.21 | 0.05 | 0.12 | TRUE |