Best TWAS P=2.37e-08 · Best GWAS P=3.83e-07 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Subcutaneous | NEIL1 | 0.05 | 0.03 | lasso | 5 | 0.02 | 1.6e-02 | 4.8 | 5.1 | 2.9e-07 | 0.98 | 0.03 | 0.96 | FALSE |
| 2 | GTEx | Adrenal Gland | MAN2C1 | 0.20 | 0.24 | lasso | 6 | 0.21 | 4.3e-08 | 5.0 | 5.5 | 4.7e-08 | 0.98 | 0.02 | 0.98 | FALSE |
| 3 | GTEx | Brain Caudate basal ganglia | MAN2C1 | 0.23 | 0.24 | enet | 20 | 0.22 | 7.9e-07 | 5.1 | 5.4 | 5.4e-08 | 0.89 | 0.02 | 0.97 | FALSE |
| 4 | The Cancer Genome Atlas | Esophageal Carcinoma | SNUPN | 0.18 | 0.11 | lasso | 5 | 0.07 | 2.6e-03 | 5.0 | 5.6 | 2.4e-08 | 0.96 | 0.00 | 0.89 | TRUE |