[Hub]/) : Traits : Hand grip strength (right) :

chr20:46,838,455-48,591,758

Best TWAS P=3.51e-10 · Best GWAS P=1.58e-09 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex ARFGEF2 0.09 0.05 lasso 8 0.10 9.2e-13 6.0 -5.7 1.6e-08 -0.83 0.01 0.99 FALSE
2 GTEx Cells Transformed fibroblasts STAU1 0.08 0.03 lasso 6 0.02 2.3e-02 5.5 5.8 6.4e-09 0.85 0.04 0.88 FALSE
3 GTEx Colon Sigmoid CSE1L 0.18 0.12 lasso 11 0.09 4.4e-04 5.8 -5.9 4.5e-09 -0.81 0.02 0.97 FALSE
4 GTEx Esophagus Mucosa CSE1L 0.09 0.06 lasso 4 0.06 6.9e-05 6.0 -5.2 1.7e-07 -0.81 0.02 0.98 FALSE
5 GTEx Lung CSE1L 0.10 0.09 lasso 5 0.08 6.6e-07 5.5 -5.2 2.2e-07 -0.74 0.04 0.96 FALSE
6 GTEx Skin Sun Exposed Lower leg CSE1L 0.08 0.03 lasso 2 0.03 9.5e-04 6.0 -5.7 1.4e-08 -0.82 0.02 0.96 FALSE
7 GTEx Testis ARFGEF2 0.20 0.20 lasso 7 0.24 5.4e-11 5.5 -6.1 1.2e-09 -0.93 0.03 0.97 FALSE
8 METSIM Adipose ARFGEF2 0.04 0.03 lasso 12 0.02 9.8e-05 5.7 -5.4 7.3e-08 -0.97 0.03 0.96 FALSE
9 NTR Blood SNORD12B 0.03 0.05 lasso 8 0.05 1.9e-14 5.0 -5.2 2.5e-07 -0.95 0.40 0.60 FALSE
10 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma CSE1L 0.03 0.05 lasso 1 0.03 9.3e-05 5.5 -5.5 4.6e-08 -0.76 0.02 0.97 FALSE
11 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma CSE1L 0.05 0.07 blup 50 0.07 3.2e-08 5.8 -5.5 4.9e-08 -0.81 0.02 0.98 FALSE
12 The Cancer Genome Atlas Brain Lower Grade Glioma ARFGEF2 0.05 0.04 lasso 5 0.05 3.2e-06 6.0 -6.3 3.5e-10 -0.95 0.01 0.99 TRUE
13 The Cancer Genome Atlas Testicular Germ Cell Tumors CSE1L 0.13 0.03 blup 50 0.07 1.4e-03 5.5 -5.5 3.2e-08 -0.60 0.02 0.58 FALSE