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chr20:46,838,455-48,591,758

Best TWAS P=3.51e-10 · Best GWAS P=1.58e-09 conditioned to 1

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
12	The Cancer Genome Atlas	Brain Lower Grade Glioma	ARFGEF2	0.05	0.04	lasso	5	0.05	3.2e-06	6.0	-6.3	3.5e-10	-0.95	0.01	0.99	TRUE
7	GTEx	Testis	ARFGEF2	0.20	0.20	lasso	7	0.24	5.4e-11	5.5	-6.1	1.2e-09	-0.93	0.03	0.97	FALSE
3	GTEx	Colon Sigmoid	CSE1L	0.18	0.12	lasso	11	0.09	4.4e-04	5.8	-5.9	4.5e-09	-0.81	0.02	0.97	FALSE
2	GTEx	Cells Transformed fibroblasts	STAU1	0.08	0.03	lasso	6	0.02	2.3e-02	5.5	5.8	6.4e-09	0.85	0.04	0.88	FALSE
6	GTEx	Skin Sun Exposed Lower leg	CSE1L	0.08	0.03	lasso	2	0.03	9.5e-04	6.0	-5.7	1.4e-08	-0.82	0.02	0.96	FALSE
1	CommonMind	Brain Pre-frontal Cortex	ARFGEF2	0.09	0.05	lasso	8	0.10	9.2e-13	6.0	-5.7	1.6e-08	-0.83	0.01	0.99	FALSE
13	The Cancer Genome Atlas	Testicular Germ Cell Tumors	CSE1L	0.13	0.03	blup	50	0.07	1.4e-03	5.5	-5.5	3.2e-08	-0.60	0.02	0.58	FALSE
10	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	CSE1L	0.03	0.05	lasso	1	0.03	9.3e-05	5.5	-5.5	4.6e-08	-0.76	0.02	0.97	FALSE
11	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	CSE1L	0.05	0.07	blup	50	0.07	3.2e-08	5.8	-5.5	4.9e-08	-0.81	0.02	0.98	FALSE
8	METSIM	Adipose	ARFGEF2	0.04	0.03	lasso	12	0.02	9.8e-05	5.7	-5.4	7.3e-08	-0.97	0.03	0.96	FALSE
4	GTEx	Esophagus Mucosa	CSE1L	0.09	0.06	lasso	4	0.06	6.9e-05	6.0	-5.2	1.7e-07	-0.81	0.02	0.98	FALSE
5	GTEx	Lung	CSE1L	0.10	0.09	lasso	5	0.08	6.6e-07	5.5	-5.2	2.2e-07	-0.74	0.04	0.96	FALSE
9	NTR	Blood	SNORD12B	0.03	0.05	lasso	8	0.05	1.9e-14	5.0	-5.2	2.5e-07	-0.95	0.40	0.60	FALSE