TWAS hub - STAU1

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0880	0.0320	0.00015	-0.001	0.013	0.002	0.013	-0.002	0.39000	0.0097	0.180	0.0087	0.610
2	GTEx	Adrenal Gland	0.1475	0.0614	0.00360	0.000	NA	0.004	NA	-0.001	0.31000	NA	0.210	NA	0.370
3	GTEx	Cells Transformed fibroblasts	0.0840	0.0350	0.00180	0.034	NA	0.006	NA	0.015	0.00130	NA	0.110	NA	0.023
4	GTEx	Testis	0.1190	0.0460	0.00048	0.069	NA	0.016	NA	0.033	0.00056	NA	0.060	NA	0.013
5	TCGA	Breast Invasive Carcinoma	0.0125	0.0080	0.00670	0.012	0.008	0.006	NA	0.005	0.00130	0.0061	0.014	NA	0.034

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	3	4	5
Intelligence (Savage-Jansen 2018)	7.6	23.5	62.9	-6.3	7.9	3.4	1.8
Verbal and Numeric Reasoning (VNR)	7.6	18.1	40.1	-5.7	6.3	3.6	2.4
Ever depressed for a whole week	7.5	9.2	26.5	-5.1	4.2	0.9	1.1
Forced vital capacity (FVC)	6.6	25.3	65.1	-3.9	8.1	-1.3	-6.7
Forced vital capacity (FVC), Best measure	6.4	23.3	57.0	-4.7	7.5	-0.6	-6.1
Comparative height size at age 10	5.6	30.7	69.7	-3.2	8.3	-3.1	-8.0
Schizophrenia vs Biploar Disorder	5.4	7.1	13.1	-3.0	3.6	3.0	2.2
Ever unenthusiastic/disinterested for a whole week	5.1	6.2	16.4	-4.1	3.7	0.2	-0.9
Standing height	5.1	50.3	146.7	-5.3	12.1	-2.1	-8.5
Forced expiratory volume in 1-second (FEV1)	4.8	16.2	36.8	-3.5	6.1	-1.5	-5.5
Height	4.7	90.1	269.0	-6.4	16.4	-3.2	-11.4
Reaction Time	4.6	8.8	22.0	-4.1	4.7	2.3	0.4
Frequency of depressed mood in last 2 weeks	4.4	6.2	21.4	-2.6	4.6	1.6	0.5
Forced expiratory volume in 1-second (FEV1), Best measure	4.4	14.1	29.7	-3.7	5.5	-1.0	-5.1
Mean time to correctly identify matches	4.4	8.4	22.5	-4.1	4.7	1.8	-0.2
Loneliness, isolation	4.4	6.0	24.3	-0.9	4.9	2.2	0.6
Hand grip strength (right)	3.9	10.6	33.8	-3.1	5.8	-0.9	-3.0
Financial difficulties in last 2 years	3.8	5.1	10.8	-1.4	2.0	2.9	3.3
Leg fat percentage (left)	3.8	13.6	32.0	5.7	-4.7	0.6	3.6
Sitting height	3.7	26.1	93.1	-4.2	9.7	0.4	-4.5
Arm fat percentage (left)	3.7	14.7	25.8	5.1	-4.9	1.3	4.7
Leg fat percentage (right)	3.6	13.2	31.1	5.6	-4.5	0.5	3.7
Arm fat percentage (right)	3.4	13.3	25.6	5.1	-4.7	1.0	4.2
Bipolar Disorder (2011)	3.2	3.1	10.4	2.2	-3.2	0.0	-0.1
Fluid intelligence score	3.2	6.7	12.9	-3.5	3.6	2.3	1.8
Hand grip strength (left)	3.1	8.1	25.5	-2.4	5.0	-1.0	-2.9
Body fat percentage	3.0	12.0	26.0	5.1	-4.1	1.1	4.0
Depression (Nagel 2018)	2.9	4.3	12.5	-2.3	3.5	1.9	0.3
BMI	2.9	16.7	34.4	5.9	-4.7	1.0	5.1
Frequency of tiredness / lethargy in last 2 weeks	2.9	4.8	13.0	-2.9	3.6	1.5	0.3
Happiness	2.9	3.6	12.1	-1.7	3.5	1.1	-1.3
Peak expiratory flow (PEF)	2.9	6.7	13.0	-1.9	3.6	-2.1	-3.5
Qualifications: College or University degree	2.8	8.9	23.6	-4.9	4.5	0.2	-0.8
Frequency of unenthusiasm / disinterest in last 2 weeks	2.7	3.6	7.0	-2.6	2.3	2.1	1.0
Ever highly irritable/argumentative for 2 days	2.7	3.3	14.0	-0.9	3.7	1.2	-0.5
Number of children fathered	2.6	3.0	8.3	2.9	-2.2	-0.4	1.2
Smoking status: Previous	2.6	3.8	12.2	-0.4	3.5	2.6	0.4
Body mass index (BMI)	2.5	10.5	22.1	4.7	-3.7	0.9	4.0
Qualifications: A levels/AS levels or equivalent	2.5	5.6	19.2	-2.9	4.4	0.2	-0.8
Hypertension (Self-reported)	2.5	7.0	12.7	-2.1	-3.6	2.8	3.2
Trunk fat-free mass	2.4	14.0	44.5	-1.4	6.7	-1.7	-4.5
Trunk predicted mass	2.4	13.5	43.0	-1.4	6.6	-1.7	-4.4
Mouth/teeth dental problems: Mouth ulcers	2.4	3.7	11.8	0.1	1.7	-2.0	-3.4
Alzheimer’s Disease (in father)	2.3	2.4	6.9	-2.2	2.6	0.4	-0.3
Trunk fat percentage	2.3	9.1	21.8	4.7	-3.3	1.0	3.4
High blood pressure	2.3	6.4	15.0	-1.6	-3.9	2.4	2.9
Medication: Cholesterol lowering	2.3	3.5	10.3	-1.4	-0.4	2.3	3.2
Qualifications: O levels/GCSEs or equivalent	2.3	3.6	9.2	-1.6	3.0	2.5	0.5
Friendships satisfaction	2.3	2.8	6.5	-2.5	2.3	0.5	-1.5
Mother’s age at death	2.3	2.9	4.8	2.0	-1.8	2.2	1.5
Financial situation satisfaction	2.3	2.9	6.4	-1.5	1.8	2.5	1.5
Bipolar Disorder (2018)	2.2	3.4	8.8	1.9	-3.0	-1.8	-1.2
Cardiovascular Disease	2.2	7.4	12.7	-3.5	-2.6	2.3	3.6
Birth weight of first child	2.2	3.9	13.8	-1.2	3.7	-0.4	-2.1
Medication for cholesterol, blood pressure or diabetes	2.2	3.6	7.6	1.0	2.3	-2.0	-2.8
Lung FVC	2.1	10.6	22.6	-3.6	4.8	0.9	-4.1
Lung cancer (father)	2.1	2.5	6.9	0.6	0.1	2.6	2.3
Medication: Blood pressure	2.1	3.8	9.3	-1.3	-3.0	1.7	2.2
Family relationship satisfaction	2.1	2.6	7.1	-2.0	2.7	0.6	-1.4
Average weekly champagne plus white wine intake	2.1	2.9	11.0	1.1	-3.3	-0.2	1.5
High blood pressure (mother)	2.0	2.9	6.5	1.8	-2.5	0.6	2.0
Time employed in main current job	2.0	2.3	6.0	2.5	-1.6	-1.1	-1.2
Commuting to job workplace: Walk	2.0	2.1	7.3	-0.5	2.7	1.3	1.2
Vascular/heart problems diagnosed by doctor	2.0	5.4	13.8	1.6	3.7	-1.9	-2.7
Number of treatments/medications taken	1.9	3.4	8.6	-0.3	-2.4	1.7	2.9
Allergy or Eczema	1.8	4.8	8.9	-2.0	2.0	2.7	3.0
Hayfever, allergic rhinitis or eczema	1.8	3.9	11.4	-1.8	0.6	2.2	3.4
Qualifications: None of the above	1.8	3.9	9.8	2.8	-3.1	-1.4	0.2
Tense / ‘highly strung’	1.8	3.0	7.9	-2.5	2.8	0.2	-1.0
Number of full sisters	1.8	2.2	4.2	1.8	-0.7	2.0	1.8
Number of self-reported non-cancer illnesses	1.8	3.1	8.0	0.3	-1.7	2.1	2.8
Ovarian Cancer	1.7	2.2	6.5	-2.5	2.0	-0.4	-0.5
Systolic Blood Pressure	1.7	8.8	29.1	-2.3	-5.4	0.6	3.0
Past tobacco smoking	1.7	3.2	10.3	0.1	-3.2	-2.3	-0.5
Mouth/teeth dental problems: Bleeding gums	1.7	2.2	9.3	3.0	0.1	-0.9	1.1
Whole body fat-free mass	1.7	9.5	32.0	-0.5	5.7	-1.3	-3.6
Miserableness	1.7	2.9	11.1	-1.4	3.3	0.9	0.8
Major Depression (MDD)	1.6	2.0	7.7	-2.8	1.3	0.6	0.4
Heart attack	1.6	2.1	6.2	-0.0	-2.5	1.4	1.5
Mouth/teeth dental problems: Dentures	1.6	2.7	5.5	1.5	-1.1	2.2	2.3
Leg fat mass (right)	1.6	6.3	19.8	4.4	-2.2	0.5	2.5
Forced expiratory volume in 1-second (FEV1), predicted	1.6	3.4	10.1	-1.2	3.2	-0.4	-2.2
Whole body water mass	1.6	9.4	31.6	-0.5	5.6	-1.4	-3.6
Arm fat mass (left)	1.6	6.4	17.2	4.1	-2.4	0.9	2.9
Eye problems/disorders: Glaucoma	1.6	1.9	4.2	1.6	-1.6	-2.1	-0.6
Leg fat mass (left)	1.6	6.4	21.3	4.6	-2.3	0.4	2.2
Body Mass Index (BMI) (2010)	1.5	2.1	3.6	1.5	-1.9	1.5	1.5
Medication for hormone replacement therapy	1.5	1.7	4.8	0.7	-0.2	1.7	2.2
Taking other prescription medications	1.5	2.4	4.8	-0.3	-2.1	1.5	2.2
Tinnitus: Yes, but not now, but have in the past	1.5	1.6	3.7	0.8	-0.3	-1.9	-1.8
Number of incorrect matches in round	1.5	2.5	9.3	1.3	-3.0	1.0	0.8
Birth weight	1.5	3.2	11.7	1.7	3.4	0.4	-1.1
Long-standing illness, disability or infirmity	1.5	2.2	4.7	-1.4	0.5	2.1	2.2
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.5	3.2	9.9	-3.1	1.8	-0.5	-1.6
High cholesterol (Self-reported)	1.5	2.7	7.3	-2.7	0.8	1.2	2.1
Diabetes (father)	1.4	1.7	4.6	2.1	-1.7	-0.9	0.4
Arm fat-free mass (right)	1.4	6.9	24.7	0.2	5.0	-1.1	-3.0
Arm predicted mass (right)	1.4	7.2	27.3	-0.1	5.2	-0.8	-2.8
Knee pain experienced in last month	1.4	2.2	8.6	2.9	-1.5	0.1	-0.2
Medication: Paracetamol	1.4	2.2	7.6	2.8	-1.5	-0.4	0.8
Arm fat-free mass (left)	1.4	6.9	23.4	0.3	4.8	-1.1	-3.1
Chronic bronchitis/emphysema (father)	1.3	1.5	3.3	1.8	-1.8	-0.6	-0.7
Had other major operations	1.3	1.6	5.6	-0.6	-0.6	1.3	2.4
Arm fat mass (right)	1.3	5.3	15.5	3.9	-2.0	0.5	2.6
Number of full brothers	1.3	1.7	4.0	1.0	-0.8	2.0	1.7
Wheeze or whistling in the chest in last year	1.3	2.3	7.1	2.7	-1.6	0.7	1.3
Whole body fat mass	1.3	5.4	18.3	4.3	-1.7	0.6	2.3
Medication for cholesterol	1.3	1.9	5.1	1.0	1.7	-0.8	-2.3
Commuting to job workplace: Cycle	1.3	1.5	3.9	-2.0	1.3	1.2	0.7
Heart attack/myocardial infarction (self-reported)	1.3	1.7	4.3	-0.3	-2.1	1.4	1.5
Arm predicted mass (left)	1.3	6.6	23.5	0.2	4.8	-0.9	-2.9
Schizophrenia (2014)	1.2	2.6	4.8	-1.2	2.2	2.2	1.5
Neuroticism	1.2	2.9	10.6	-1.3	3.3	1.3	0.8
Bilateral oophorectomy (both ovaries removed)	1.2	1.4	6.1	0.2	0.6	2.5	0.6
Serious illness, injury or assault to yourself	1.2	1.4	5.7	-2.4	1.0	0.4	0.1
Worrier / anxious feelings	1.2	2.2	4.4	-1.1	2.1	1.9	1.4
Qualifications: NVQ or HND or HNC or equivalent	1.2	1.4	4.5	0.4	-0.9	1.2	2.1
Osteoporosis (self-reported)	1.2	1.4	5.9	0.9	-2.4	-0.6	0.3
Commuting to job workplace: Public transport	1.2	1.4	6.0	-0.1	2.5	0.8	0.6
Basal metabolic rate	1.2	6.7	23.8	0.2	4.9	-1.2	-2.8
Schizophrenia (2018)	1.1	2.2	5.1	-0.9	2.3	1.7	1.5
Systolic blood pressure, automated reading	1.1	3.1	11.7	-0.4	-3.4	-0.5	1.9
Supplements: Zinc	1.1	1.2	2.2	-1.2	0.9	1.3	1.5
Hearing difficulty/problems with background noise	1.1	1.8	4.7	-0.2	2.1	2.2	0.1
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.1	1.3	2.8	-1.7	0.8	1.3	1.2
Qualifications: nursing, teaching	1.1	1.7	5.8	-2.4	1.4	0.6	-0.4
Eye problems/disorders: Cataract	1.1	1.2	4.4	0.9	-2.1	-0.7	-0.6
Back pain experienced in last month	1.1	1.6	5.7	1.5	0.5	-0.4	-2.4
Smoking status: Current	1.1	1.7	4.8	2.2	-1.6	-0.7	-0.9
Medication: Bendroflumethiazide	1.1	1.7	4.4	-1.5	-2.1	1.1	0.8
Ever smoked	1.1	1.9	5.0	-0.1	2.1	2.2	0.3
Number of operations (self-reported)	1.1	1.7	5.3	1.1	-2.3	1.0	1.0
Worry (Nagel 2018)	1.0	2.1	3.6	-1.7	1.9	1.7	1.0
Coronary Artery Disease (CAD)	1.0	1.2	3.6	0.5	-1.9	-0.3	1.4
HDL Cholesterol	1.0	1.6	5.1	2.3	-0.9	-1.0	-1.1
Average weekly spirits intake	1.0	1.2	2.8	-1.4	1.7	-0.9	-0.7
Average weekly fortified wine intake	1.0	1.2	5.4	-2.3	0.7	0.1	-0.1
Diverticular disease/diverticulitis (self-reported)	1.0	1.2	4.2	1.3	-2.0	-0.0	0.5
Trunk fat mass	1.0	4.5	16.0	4.0	-1.3	0.6	2.1
Alcohol usually taken with meals	1.0	1.6	3.7	-0.1	-1.9	1.7	1.3
Mouth/teeth dental problems	1.0	1.6	7.4	-2.7	0.3	0.2	-0.7
Medication: Ramipril	1.0	1.3	3.2	-0.1	-1.8	1.1	1.4
Medication: Simvastatin	1.0	1.4	5.3	-1.0	-0.6	0.7	2.3
Length of working week for main job	1.0	1.1	4.4	0.7	-0.7	0.2	2.1
Medication: Paracetamol	1.0	1.7	4.6	2.1	-1.7	-0.9	0.2
Medication: Amlodipine	1.0	1.5	4.2	-1.6	-2.0	0.8	-0.3
Health satisfaction	1.0	1.4	3.6	-0.5	-1.2	1.9	1.2
Medication: Ibuprofen	1.0	1.2	3.9	2.0	-1.3	-0.6	-0.1
Heart disease (mother)	1.0	1.3	3.6	-1.2	1.9	1.1	0.2
Illness, injury, bereavement, stress in last 2 years	1.0	1.2	2.6	1.6	-0.5	-1.2	-1.4
Ever had stillbirth, spontaneous miscarriage or termination	1.0	1.0	2.0	1.4	-0.5	1.3	1.1
Osteoarthritis (self-reported)	1.0	1.3	4.2	0.9	-0.3	1.1	2.0
Hearing aid user	1.0	1.2	3.3	-0.3	1.2	1.8	1.1
Myopia	1.0	1.4	4.6	0.3	-2.1	1.0	1.1
Depressed Affect (Nagel 2018)	0.9	2.0	7.4	-0.7	2.7	1.1	0.8
Crohns Disease (2017)	0.9	2.1	10.0	3.2	-0.6	-0.2	0.1
Fasting Glucose	0.9	1.1	3.6	0.9	-1.9	0.1	1.1
Hearing difficulty/problems: Yes	0.9	1.4	4.5	0.2	0.7	2.1	1.4
Pack years adult smoking proportion	0.9	1.3	4.6	2.2	-0.8	-1.1	0.1
Medication: Atenolol	0.9	1.1	3.7	-0.8	-1.9	-0.8	0.7
Frequency of tenseness / restlessness in last 2 weeks	0.9	1.5	6.1	-1.1	2.5	0.2	0.2
Pain all over the body in last month	0.9	0.9	3.2	-0.7	0.5	0.8	1.8
Diabetes (self-reported)	0.9	1.4	3.3	-1.3	0.1	1.8	1.3
Hair/balding pattern: Pattern 3	0.9	1.3	4.9	-2.2	1.3	0.3	-0.2
Hair/balding pattern: Pattern 4	0.9	2.2	5.3	0.9	-2.3	-1.4	-1.8
Medication: Ventolin 100micrograms inhaler	0.9	1.2	3.9	2.0	-1.2	-0.4	-0.7
Seen a psychiatrist for nerves, anxiety, tension or depression	0.9	1.2	3.0	-1.2	0.8	1.7	1.0
Emphysema/chronic bronchitis	0.9	1.0	3.0	1.3	-1.7	0.5	-0.3
Had major operations	0.9	1.1	2.9	0.6	-1.3	1.7	0.6
Leg predicted mass (right)	0.9	4.7	17.7	0.1	4.2	-0.8	-2.2
Diastolic blood pressure, automated reading	0.9	2.7	8.1	-1.1	-2.8	-2.1	0.2
Neuroticism (Nagel 2018)	0.8	1.8	6.1	-0.8	2.5	1.0	1.2
LDL Cholesterol	0.8	1.2	4.5	-0.9	2.1	0.7	0.6
Rheumatoid Arthritis	0.8	1.2	4.2	2.1	-1.2	-0.4	-0.0
Smoking Status	0.8	1.8	5.6	1.1	2.4	1.4	-0.6
Leg fat-free mass (left)	0.8	4.1	15.4	0.5	3.9	-0.9	-2.0
Current tobacco smoking	0.8	1.3	3.2	1.8	-1.5	-0.4	-0.8
Qualifications: CSEs or equivalent	0.8	1.0	2.6	1.4	-0.7	-1.6	-0.2
Supplements: Glucosamine	0.8	1.0	2.6	-0.2	-0.4	1.5	1.6
Medication: Levothyroxine sodium	0.8	1.3	2.3	-1.5	1.3	-0.9	-1.4
Leg predicted mass (left)	0.8	4.1	15.1	0.6	3.9	-0.9	-2.1
Allergy	0.8	1.9	4.8	0.7	-0.3	-2.1	-2.2
Father’s age at death	0.8	1.1	4.9	2.2	-0.2	-0.7	-0.4
Number of live births	0.8	1.2	2.9	1.5	-1.7	0.2	-0.8
Pulse wave reflection index	0.8	1.0	4.1	-2.0	0.2	0.4	0.7
Glaucoma (self-reported)	0.8	1.0	3.2	1.1	-1.8	-0.7	0.1
Hypothyroidism/myxoedema (self-reported)	0.8	1.6	3.8	-2.0	1.2	-1.3	-1.2
Chronic bronchitis/emphysema (mother)	0.8	0.9	2.2	-0.7	-0.5	1.2	1.5
Neck or shoulder pain in last month	0.8	1.1	2.6	1.6	1.3	1.2	0.2
Leg fat-free mass (right)	0.8	4.5	17.3	0.1	4.2	-0.8	-2.2
Handedness (chirality/laterality): Left-handed	0.8	1.0	4.6	2.1	-0.4	0.4	-0.1
Average weekly beer plus cider intake	0.8	1.1	2.8	0.9	-1.4	-1.7	0.3
Irritability	0.8	1.3	3.7	-0.8	1.9	-0.3	-1.4
Crohns Disease (2012)	0.7	1.0	4.5	2.1	-0.6	-0.1	0.7
Hypothyroidism (self reported)	0.7	1.5	6.4	-2.5	1.1	-0.0	0.2
Maternal smoking around birth	0.7	1.0	3.0	-1.1	1.7	0.9	0.2
Waist circumference	0.7	2.6	6.1	2.3	-0.4	1.2	2.5
Comparative body size at age 10	0.7	2.0	4.9	2.2	-2.2	0.2	0.1
Shortness of breath walking on level ground	0.7	0.8	2.6	1.6	-1.0	-0.6	-0.4
Medication for pain relief, constipation, heartburn	0.7	1.3	4.0	-0.5	2.0	-0.4	-1.3
Commuting to job workplace: Car/motor vehicle	0.7	0.8	3.6	0.1	-1.9	-0.7	-0.1
Diabetes diagnosed by doctor	0.7	1.1	2.2	-1.2	-0.3	1.5	1.3
Wears glasses or contact lenses	0.7	0.8	2.4	1.6	-0.4	-1.1	-0.3
Medication: Blood pressure	0.7	1.3	4.6	-1.1	-2.1	0.2	0.9
Pain experienced in last month	0.7	1.2	5.3	-2.3	0.5	0.4	0.6
Heart disease (siblings)	0.7	0.9	2.2	0.3	1.2	1.5	0.9
Chronotype (morning person)	0.6	1.3	2.9	-1.7	0.9	-1.1	-1.3
Had menopause	0.6	0.7	1.1	1.0	1.1	0.4	-1.1
Neuroticism score	0.6	1.2	5.3	0.2	2.3	0.6	0.2
Alcohol intake versus 10 years previously	0.6	0.8	2.7	0.0	-0.6	1.0	1.6
Illnesses of mother	0.6	0.8	2.8	0.2	1.7	-0.8	-0.5
Pulse wave Arterial Stiffness index	0.6	0.7	1.9	-1.4	1.0	-0.6	-0.0
High blood pressure (siblings)	0.6	0.8	1.5	0.2	-1.2	1.2	1.1
Worry too long after embarrassment	0.6	1.0	1.3	1.2	1.1	-1.1	-1.0
Reason for reducing amount of alcohol drunk: Health precaution	0.6	0.7	1.7	1.2	0.1	0.5	1.3
Medication: Omeprazole	0.6	0.8	1.5	1.0	-1.2	-0.6	-0.9
Medication: Aspirin	0.6	0.8	2.6	-1.6	-0.6	0.7	0.7
Supplements: Vitamin C	0.6	0.7	2.8	-0.4	1.7	0.5	-0.2
Medication: Aspirin	0.6	0.7	2.9	-1.7	-0.7	0.2	0.4
Medication: Atorvastatin	0.6	0.7	2.4	-1.5	-0.3	1.0	-0.1
Pack years of smoking	0.6	0.8	3.1	1.8	-0.6	-0.9	0.2
Alzheimer’s Disease (including proxy)	0.5	0.7	1.6	-1.3	0.9	1.1	0.2
Breast Cancer	0.5	1.2	3.3	-1.5	1.8	-0.1	0.6
Prostate Cancer	0.5	0.6	1.8	-0.6	-1.3	-0.9	-0.6
HbA1C	0.5	0.5	1.1	1.0	-0.7	-0.8	-0.7
Neuroticism (2016)	0.5	0.7	1.6	0.0	1.2	1.0	0.9
Primary Biliary Cirrhosis	0.5	0.6	1.4	1.2	-1.2	-0.6	-0.2
Triglycerides	0.5	0.8	3.3	-0.2	-0.1	0.8	1.8
Blood White Count	0.5	3.3	8.8	1.5	-0.1	2.4	3.0
Lung FEV1/FVC ratio	0.5	2.7	11.5	1.1	-3.4	-0.6	0.8
Sensitivity / hurt feelings	0.5	0.8	2.6	1.6	0.1	0.4	1.2
Other serious medical condition/disability diagnosed by doctor	0.5	0.6	1.3	-0.7	0.6	1.1	1.0
Ever used hormone-replacement therapy (HRT)	0.5	0.6	2.6	1.6	-0.6	0.1	0.3
Prospective memory result	0.5	0.6	1.9	1.4	-0.8	-0.4	-0.5
Seen doctor (GP) for nerves, anxiety, tension or depression	0.5	0.8	2.2	-1.5	1.2	0.5	0.4
Gout (self-reported)	0.5	0.7	2.5	-0.2	1.6	-0.3	-0.8
Suffer from ‘nerves’	0.5	0.8	3.9	0.1	2.0	0.4	0.3
Ever taken oral contraceptive pill	0.5	0.6	2.2	-0.8	1.5	0.2	-0.2
Illnesses of father: High blood pressure	0.5	0.6	1.8	0.5	-1.3	-1.0	0.1
Age started oral contraceptive pill	0.5	0.6	1.9	0.5	0.8	-0.1	-1.4
Deep venous thrombosis (DVT) (self-reported)	0.5	0.6	1.2	-0.6	0.6	-1.1	-1.1
Age at First Birth	0.4	0.6	2.4	-0.6	-0.4	1.6	0.4
Ulcerative Colitis	0.4	0.6	1.0	-0.6	-0.8	-1.0	-0.9
Ever had hysterectomy (womb removed)	0.4	0.4	1.7	-0.5	0.2	1.3	0.5
Vitamin and mineral supplements	0.4	0.6	2.4	0.4	-1.5	0.2	0.5
Medication: Metformin	0.4	0.6	1.3	0.5	-0.9	0.8	1.1
Fed-up feelings	0.4	0.8	2.0	0.8	1.4	1.0	0.2
Relative age voice broke	0.4	0.6	1.1	-1.0	0.3	1.0	0.8
Nervous feelings	0.4	0.7	2.0	-0.7	1.4	-0.3	-1.0
Hayfever/allergic rhinitis (self-reported)	0.4	0.6	2.0	0.8	0.5	0.3	1.4
Weight	0.4	1.8	4.7	2.2	2.0	-0.1	-0.1
Falls in the last year	0.4	0.5	1.6	0.9	-0.0	1.3	-0.1
Asthma	0.4	0.7	1.8	1.2	0.6	1.3	0.3
Medication: Ibuprofen (e.g. Nurofen)	0.4	0.5	1.2	0.8	-1.1	-0.5	0.5
Loud music exposure frequency	0.4	0.5	1.3	1.1	-0.2	-0.9	-0.4
Blood clot in the leg (DVT)	0.4	0.5	1.1	-0.4	0.3	-1.1	-1.0
Eye problems/disorders: None of the above	0.4	0.5	1.2	-0.7	1.1	0.6	0.5
Mood swings	0.4	0.7	2.9	0.7	-0.4	-1.7	-0.1
Mineral and other dietary supplements	0.4	0.5	1.9	1.4	-0.3	-0.7	-0.3
Breast cancer (self-reported)	0.4	0.4	1.0	0.1	0.9	1.0	0.6
Medication: Gliclazide	0.4	0.5	1.1	-0.2	0.9	-0.6	-1.1
Guilty feelings	0.4	0.6	1.7	1.3	-0.1	-1.0	-0.4
Supplements: Fish oil (including cod liver oil)	0.4	0.5	1.3	-1.1	-0.2	0.9	0.7
Risk taking	0.4	0.6	1.5	0.7	-1.2	-0.9	-0.3
Unable to work because of sickness or disability	0.4	0.6	1.8	-0.9	1.3	-0.4	-0.0
Supplements: Calcium	0.4	0.4	0.8	0.5	0.2	0.9	0.9
Alcohol drinker status: Previous	0.4	0.4	1.4	-1.2	0.5	0.4	0.4
Alzheimer’s Disease (in mother)	0.3	0.3	1.4	-0.0	0.1	1.2	0.4
Mean Putamen Volume	0.3	0.3	0.9	-0.7	-0.3	-0.1	0.9
Lupus	0.3	0.4	0.9	-0.3	1.0	-0.0	-0.9
Blood Platelet Count	0.3	3.3	11.4	2.1	-0.2	-3.4	-0.6
Respiratory disease	0.3	0.6	2.0	1.4	0.8	0.6	-0.5
Type 2 Diabetes (T2D) (2018)	0.3	0.6	1.3	0.8	-1.1	0.5	0.8
Diabetes (mother)	0.3	0.4	1.0	-0.2	-0.9	-1.0	0.4
Hip circumference	0.3	1.3	3.6	1.6	0.4	0.5	1.9
Exposure to tobacco smoke at home	0.3	0.3	0.8	-0.9	-0.1	-0.9	0.2
Headache pain in last month	0.3	0.5	1.9	-0.6	1.4	-0.4	-0.2
Pulse wave peak to peak time	0.3	0.4	1.2	1.1	-0.3	0.5	-0.4
Medication: Allopurinol	0.3	0.4	1.7	0.1	1.3	-0.5	-0.1
Overall health rating	0.3	0.6	1.7	-0.1	-0.4	1.3	1.1
Leg pain on walking	0.3	0.4	1.8	0.1	0.3	1.3	0.1
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.3	0.3	0.9	-0.1	-0.9	0.9	0.1
Asthma (self-reported)	0.3	0.5	1.2	1.0	0.6	1.1	0.5
Tinnitus: Yes, now most or all of the time	0.3	0.3	1.1	0.4	-0.4	0.4	1.1
Medication: Lisinopril	0.3	0.4	1.2	-1.1	-0.9	-0.1	0.3
Alcohol drinker status: Never	0.3	0.3	1.3	0.3	0.1	1.1	0.4
Ever had prostate specific antigen (PSA) test	0.3	0.3	1.0	-0.2	-0.6	1.0	0.4
Irritable Bowel Disease (IBD)	0.2	0.5	1.7	1.3	-0.4	-0.4	-0.5
Type 2 Diabetes (T2D) (2012)	0.2	0.2	1.0	1.0	-0.1	-0.4	-0.1
Blood Red Count	0.2	2.1	8.3	0.9	2.9	1.0	0.3
Waist Hip Ratio (WHR)	0.2	0.7	2.7	-0.6	1.6	0.5	-0.6
Relative age of first facial hair	0.2	0.4	1.1	-0.5	1.0	-0.2	-0.7
Angina	0.2	0.3	1.1	0.0	-0.3	-0.3	1.1
Heel bone mineral density (BMD) T-score, automated (left)	0.2	0.4	1.5	0.1	-0.2	-1.2	0.5
Multivitamins +/- minerals	0.2	0.3	1.1	-0.0	0.4	0.4	1.0
Hair/balding pattern: Pattern 2	0.2	0.3	1.1	1.0	0.3	0.6	0.2
Heel bone mineral density (BMD) T-score, automated (right)	0.2	0.5	1.7	-0.4	-0.2	-1.3	0.6
Illnesses of siblings	0.2	0.3	0.9	0.1	0.1	-0.9	-0.9
Pulse rate	0.2	0.3	1.0	-0.2	1.0	0.3	0.5
Serious illness, injury or assault of a close relative in last 2 years	0.2	0.2	0.8	0.3	0.9	0.3	0.2
Depression (self-reported)	0.2	0.2	0.6	-0.6	0.8	-0.1	0.2
Medication: Lansoprazole	0.2	0.2	0.8	0.9	-0.3	0.1	0.1
Impedance of arm (left)	0.2	0.7	2.4	-1.6	-0.7	0.5	0.6
Breastfed as a baby	0.2	0.2	0.6	0.8	0.7	0.2	-0.3
Exposure to tobacco smoke outside home	0.2	0.3	0.7	-0.8	0.1	-0.8	0.4
Mouth/teeth dental problems: Loose teeth	0.2	0.2	1.0	1.0	-0.0	0.3	0.2
Angina (self-reported)	0.2	0.2	1.2	0.0	-0.1	-0.2	1.1
Migraine (self-reported)	0.2	0.2	1.1	0.1	1.1	0.1	0.1
Medication: Seretide 50 evohaler	0.2	0.2	0.7	0.4	-0.8	-0.1	-0.2
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.2	0.2	1.0	1.0	-0.4	-0.3	-0.1
Illnesses of father: Heart disease	0.2	0.2	0.9	0.3	1.0	-0.3	-0.2
Illnesses of father: None of the above (group 1)	0.2	0.2	0.5	-0.3	-0.0	0.7	-0.7
Fractured/broken bones in last 5 years	0.2	0.3	1.2	-0.4	-1.1	-0.1	0.5
Cholesterol lowering medication	0.2	0.3	0.5	-0.7	-0.5	-0.7	0.6
Medication: Omeprazole (e.g. Zanprol)	0.2	0.3	1.0	0.6	-1.0	0.4	-0.0
Basal cell carcinoma (self-reported)	0.2	0.3	0.4	-0.4	0.6	-0.6	-0.5
Ulcerative Colitis (UC)	0.1	0.3	0.8	-0.7	0.2	-0.2	-0.9
Blood Eosinophil Count	0.1	1.1	3.4	-1.3	1.8	0.4	0.1
Heel T-Score	0.1	0.9	1.7	1.3	1.0	-1.1	0.7
Hair Pigment	0.1	3.3	9.5	0.5	3.1	-0.4	-2.6
Tanning	0.1	1.1	3.8	0.2	2.0	-0.6	-1.2
Eye problems/disorders: Diabetes related eye disease	0.1	0.2	0.5	-0.4	0.4	-0.7	-0.1
Medication: Co-codamol	0.1	0.1	0.5	-0.3	0.2	0.7	-0.1
Severe depression (siblings)	0.1	0.1	0.6	0.2	0.3	-0.1	0.8
Age when periods started (menarche)	0.1	0.3	0.5	-0.7	-0.3	0.4	0.7
Stomach or abdominal pain in last month	0.1	0.2	0.5	0.6	-0.2	0.0	0.7
Impedance of leg (left)	0.1	0.2	0.8	-0.9	-0.1	-0.3	-0.6
Impedance of arm (right)	0.1	0.4	1.9	-1.4	-0.4	-0.1	-0.2
Noisy workplace	0.1	0.1	0.1	0.3	-0.1	0.4	0.4
Age at first live birth	0.1	0.3	1.0	-1.0	-0.4	0.3	0.2
Pulse rate, automated reading	0.1	0.3	0.8	0.5	0.9	0.3	-0.4
Alcohol intake frequency.	0.1	0.2	0.8	-0.9	-0.2	0.0	0.4
Chest pain or discomfort	0.1	0.2	0.4	0.4	0.7	-0.3	0.4
Age at last live birth	0.1	0.2	0.4	0.2	-0.4	0.6	-0.6
Illnesses of siblings: Diabetes	0.1	0.1	0.4	-0.6	0.1	-0.1	0.4
Average weekly red wine intake	0.1	0.2	0.7	0.1	-0.1	0.8	0.2
Ever had bowel cancer screening	0.1	0.1	0.4	0.6	-0.5	0.2	0.1
Pain type(s) experienced in last month: Hip pain	0.1	0.2	0.5	0.2	-0.5	-0.7	0.4
Impedance of whole body	0.1	0.4	1.5	-1.2	-0.5	0.2	0.3
Bipolar Disorder or Schizophrenia	0.0	0.1	0.2	0.5	-0.1	0.2	0.4
Impedance of leg (right)	0.0	0.2	0.8	-0.9	-0.0	-0.3	-0.5
Townsend deprivation index at recruitment	0.0	0.0	0.1	-0.0	-0.0	0.1	0.3

Hub : Genes

STAU1

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Trait associations