Best TWAS P=3.89e-09 · Best GWAS P=1.1e-07 conditioned to 0.0696
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Cells Transformed fibroblasts | RPL13 | 0.10 | 0.08 | enet | 8 | 0.09 | 3.7e-07 | 4.9 | -5.4 | 7.7e-08 | -0.86 | 0.02 | 0.98 | FALSE |
| 2 | GTEx | Colon Transverse | RPL13 | 0.23 | 0.17 | lasso | 4 | 0.16 | 3.7e-08 | 5.2 | -5.1 | 3.1e-07 | -0.87 | 0.01 | 0.99 | FALSE |
| 3 | GTEx | Skin Not Sun Exposed Suprapubic | RPL13 | 0.16 | 0.15 | lasso | 4 | 0.15 | 2.0e-08 | 5.1 | -5.1 | 2.9e-07 | -0.91 | 0.02 | 0.98 | FALSE |
| 4 | The Cancer Genome Atlas | Colon Adenocarcinoma | SPG7 | 0.13 | 0.01 | blup | 59 | 0.03 | 5.8e-03 | -3.6 | -5.9 | 3.9e-09 | -0.67 | 0.01 | 0.30 | TRUE |
| 5 | The Cancer Genome Atlas | Thyroid Carcinoma | SPG7 | 0.10 | 0.09 | lasso | 4 | 0.11 | 1.9e-10 | 5.0 | -5.4 | 8.5e-08 | -0.87 | 0.01 | 0.99 | FALSE |