Hub : Genes

RPL13

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 CommonMind Brain Pre-frontal Cortex 0.0820 0.0280 2.3e-05 0.035 0.049 0.043 0.050 0.039 4.2e-05 1.3e-06 5.3e-06 1.0e-06 1.2e-05
2 GTEx Adipose Subcutaneous 0.0940 0.0360 9.0e-04 0.054 NA 0.102 NA 0.065 3.3e-05 NA 1.1e-08 NA 4.9e-06
3 GTEx Adipose Visceral Omentum 0.1890 0.0690 1.2e-03 0.030 NA 0.039 NA 0.064 1.1e-02 NA 4.1e-03 NA 3.0e-04
4 GTEx Artery Aorta 0.1940 0.0530 2.1e-07 0.195 NA 0.150 NA 0.167 5.7e-11 NA 1.3e-08 NA 1.7e-09
5 GTEx Artery Tibial 0.0709 0.0303 2.6e-03 0.057 NA 0.045 NA 0.059 3.0e-05 NA 2.0e-04 NA 2.0e-05
6 GTEx Breast Mammary Tissue 0.0880 0.0380 2.4e-03 0.052 NA 0.037 NA 0.023 1.1e-03 NA 5.3e-03 NA 2.2e-02
7 GTEx Breast Mammary Tissue (Male) 0.0962 0.0766 1.3e-01 0.049 NA 0.002 NA 0.002 2.9e-02 NA 2.9e-01 NA 2.9e-01
8 GTEx Breast Mammary Tissue (Female) 0.0952 0.0727 1.1e-01 -0.004 NA -0.006 NA 0.029 4.4e-01 NA 5.2e-01 NA 4.6e-02
9 GTEx Cells Transformed fibroblasts 0.1030 0.0410 3.5e-04 0.079 NA 0.088 NA 0.086 1.6e-06 NA 3.7e-07 NA 5.7e-07
10 GTEx Colon Sigmoid 0.1710 0.0680 1.0e-03 0.175 NA 0.105 NA 0.158 8.8e-07 NA 1.5e-04 NA 3.1e-06
11 GTEx Colon Transverse 0.2340 0.0750 9.4e-06 0.170 NA 0.137 NA 0.162 1.7e-08 NA 4.8e-07 NA 3.7e-08
12 GTEx Esophagus Muscularis 0.1740 0.0510 2.5e-06 0.121 NA 0.082 NA 0.113 9.0e-08 NA 1.1e-05 NA 2.4e-07
13 GTEx Muscle Skeletal 0.1020 0.0313 2.6e-06 0.095 NA 0.090 NA 0.102 1.5e-09 NA 3.8e-09 NA 3.3e-10
14 GTEx Nerve Tibial 0.0956 0.0356 3.7e-04 0.074 NA 0.065 NA 0.066 6.5e-06 NA 2.2e-05 NA 2.0e-05
15 GTEx Skin Not Sun Exposed Suprapubic 0.1640 0.0590 1.6e-04 0.151 NA 0.138 NA 0.146 1.2e-08 NA 5.4e-08 NA 2.0e-08
16 GTEx Skin Sun Exposed Lower leg 0.1080 0.0350 6.0e-06 0.132 NA 0.125 NA 0.123 4.6e-11 NA 1.7e-10 NA 2.2e-10
17 GTEx Testis 0.2470 0.0640 1.6e-07 0.223 NA 0.195 NA 0.206 2.9e-10 NA 4.8e-09 NA 1.6e-09
18 GTEx Thyroid 0.1280 0.0440 3.2e-05 0.048 NA 0.063 NA 0.059 1.5e-04 NA 1.4e-05 NA 2.6e-05
19 METSIM Adipose 0.0541 0.0203 4.0e-04 0.047 0.016 0.048 0.044 0.047 1.2e-07 1.7e-03 1.0e-07 3.5e-07 1.2e-07
20 NTR Blood 0.0188 0.0080 2.3e-03 0.011 0.010 0.008 0.012 0.009 1.3e-04 2.1e-04 7.4e-04 5.9e-05 3.5e-04
21 TCGA Esophageal Carcinoma 0.1420 0.0720 3.3e-03 0.072 0.035 0.014 NA 0.036 2.7e-03 2.8e-02 1.2e-01 NA 2.7e-02
22 TCGA Ovarian Serous Cystadenocarcinoma 0.0340 0.0220 8.4e-03 0.012 0.024 0.016 NA 0.021 5.1e-02 8.5e-03 2.8e-02 NA 1.3e-02
23 TCGA Stomach Adenocarcinoma 0.0360 0.0230 5.4e-03 0.029 0.032 0.025 NA 0.027 3.5e-03 2.2e-03 6.5e-03 NA 4.8e-03

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23
Bipolar Disorder (2018) 1.1 1.7 4.5 -0.3 -1.2 0.3 -0.9 -2.0 0.5 -1.5 1.0 -2.0 -1.7 -0.5 -1.0 -1.5 -1.5 -1.3 -1.1 -1.8 0.0 -1.4 2.1 -1.4 -0.4 -1.2
Bipolar Disorder or Schizophrenia 2.8 6.9 14.9 -3.3 -2.9 -1.2 -2.3 -3.9 -0.7 -2.6 0.0 -2.6 -3.2 -1.1 -2.5 -3.1 -3.1 -2.9 -2.9 -3.2 -1.1 -2.8 3.7 -2.7 -1.6 -2.5
Depressed Affect (Nagel 2018) 0.2 0.4 2.2 -0.1 -0.8 -0.1 0.1 -0.3 0.6 0.9 1.5 -0.9 -0.0 -0.6 -0.5 -0.3 -0.6 -0.7 -0.6 0.0 -0.7 -0.5 0.1 -0.6 -0.4 -0.4
Depression (Nagel 2018) 0.8 1.3 4.4 1.3 -0.5 1.2 1.3 1.5 1.4 0.4 2.1 1.1 1.3 0.6 0.8 1.1 1.0 1.0 0.7 1.3 0.6 0.9 -1.4 0.9 0.8 1.0
Intelligence (Savage-Jansen 2018) 0.3 1.0 11.6 -0.4 1.8 0.5 -0.5 0.5 -0.3 3.4 -0.2 -0.7 -0.2 -1.0 -0.5 -0.3 -0.5 -0.6 0.0 0.1 -1.4 -0.6 -0.2 -0.7 -1.2 -0.9
Neuroticism (Nagel 2018) 0.2 0.4 2.9 -0.6 -1.1 0.1 0.2 0.5 0.2 -1.0 1.7 0.3 0.2 -0.6 -0.4 0.0 -0.1 -0.3 -0.4 0.3 -0.9 -0.1 -0.6 -0.1 -0.5 -0.3
Schizophrenia (2018) 2.8 5.9 15.9 -4.0 -2.7 -1.8 -2.3 -3.3 -1.4 -2.1 0.0 -1.7 -2.7 -1.0 -2.4 -2.7 -2.8 -2.7 -2.9 -2.6 -1.5 -2.5 3.1 -2.3 -1.7 -2.2
Schizophrenia vs Biploar Disorder 0.1 0.2 1.8 -1.3 -0.2 -0.8 0.1 -0.2 -0.4 -0.5 0.0 -0.2 0.2 0.0 -0.4 -0.1 -0.4 -0.4 0.4 0.2 -0.1 -0.3 0.7 -0.3 -0.1 -0.3
Worry (Nagel 2018) 1.1 2.2 6.5 -1.4 -2.0 -0.5 -1.2 -1.1 -1.5 -2.5 1.0 -0.5 -1.1 -2.0 -1.7 -1.3 -1.5 -1.4 -1.5 -1.2 -2.2 -1.4 0.6 -1.3 -1.9 -1.5
Alzheimer’s Disease (in mother) 0.4 0.5 2.1 0.2 -0.4 -1.4 -1.1 -0.9 -0.8 0.6 0.1 -0.2 -1.0 0.1 -0.2 -0.8 -0.7 -0.7 -1.1 -1.1 -0.3 -0.4 0.3 -0.3 -0.4 -0.2
Alzheimer’s Disease (in father) 0.1 0.1 0.8 0.0 -0.8 0.3 0.1 -0.4 0.9 0.5 0.4 -0.3 -0.3 0.5 0.2 -0.2 -0.2 -0.2 -0.4 -0.3 0.1 0.1 0.0 0.1 -0.1 -0.4
Alzheimer’s Disease (including proxy) 1.4 2.1 5.3 -0.4 -1.6 -1.5 -1.9 -1.7 -0.9 0.9 0.2 -1.2 -2.1 -0.4 -0.9 -1.8 -1.7 -1.7 -1.9 -2.3 -1.1 -1.3 1.1 -1.2 -1.4 -1.4
Crohns Disease (2017) 0.3 0.6 5.9 -1.3 -0.6 0.8 -0.4 -0.3 0.5 1.0 2.4 -0.3 -0.5 -0.4 -0.6 -0.7 -0.5 -0.6 -0.5 -0.5 -0.1 -0.5 0.2 -0.6 0.0 -0.4
Irritable Bowel Disease (IBD) 0.4 0.9 4.0 -2.0 -0.5 0.0 -0.7 -0.5 -0.1 0.9 1.5 -0.9 -0.7 -0.9 -1.0 -1.0 -1.0 -1.0 -1.0 -0.5 -0.8 -0.9 0.6 -1.1 -0.8 -1.1
Ulcerative Colitis (UC) 0.3 0.5 2.9 -1.7 -0.3 -0.3 -0.4 -0.2 -0.4 0.2 -0.4 -0.8 -0.5 -0.5 -0.7 -0.7 -0.7 -0.7 -0.8 -0.2 -0.7 -0.7 0.7 -0.8 -0.8 -0.9
Major Depression (MDD) 1.0 1.2 7.6 -0.1 -1.8 -1.6 -0.7 -0.4 -0.1 -2.8 0.0 -0.3 -1.4 0.2 -0.3 -1.2 -1.1 -1.1 -0.3 -1.6 -0.5 -1.1 0.8 -1.1 -0.7 -1.0
Reaction Time 0.1 0.2 1.4 -0.5 -0.1 0.1 0.5 -0.1 1.1 0.2 1.2 0.6 0.0 0.9 0.4 0.1 0.2 0.1 0.1 -0.0 0.5 0.4 -0.0 0.4 0.4 0.2
Verbal and Numeric Reasoning (VNR) 0.4 0.9 8.4 -0.4 2.3 -0.3 -0.4 0.7 -0.5 2.9 -1.3 0.3 -0.1 -0.6 -0.1 0.0 0.2 0.1 -0.1 0.6 -1.1 0.0 -0.6 -0.0 -1.0 -0.5
Breast Cancer 1.9 4.7 7.7 -2.5 -1.6 -0.7 -2.5 -1.9 -2.1 -0.7 2.2 -2.2 -2.3 -1.9 -2.3 -2.3 -2.2 -2.4 -2.7 -2.0 -2.4 -2.4 1.5 -2.3 -2.8 -2.4
Ovarian Cancer 1.0 1.3 3.7 0.5 0.4 0.8 0.9 0.8 1.4 1.4 1.9 1.2 0.7 1.8 1.5 1.0 0.9 1.0 0.5 0.8 1.0 1.3 -1.7 1.2 0.8 1.3
Prostate Cancer 0.6 0.9 2.6 0.3 -1.3 1.6 1.0 0.8 1.1 -1.2 1.6 1.0 0.9 0.7 0.9 0.9 0.8 0.8 1.1 0.5 0.7 0.7 -0.5 0.8 0.9 0.8
Age at First Birth 1.2 1.8 4.3 0.7 1.4 0.6 1.2 1.4 0.8 0.6 -0.5 1.6 1.3 0.8 1.3 1.5 1.7 1.8 1.3 2.1 0.6 1.9 -1.9 1.8 0.7 1.3
Bipolar Disorder (2011) 0.3 0.3 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 -1.2 -0.6 -1.0
Body Mass Index (BMI) (2010) 1.7 2.3 3.4 -1.6 -0.9 -1.4 -1.5 -1.6 -1.4 -0.5 -0.8 -1.6 -1.6 -1.5 -1.5 -1.6 -1.8 -1.7 -1.4 -1.6 -1.5 -1.7 1.8 -1.7 -1.4 -1.8
Coronary Artery Disease (CAD) 12.5 14.9 23.7 -4.3 -2.1 -2.3 -4.1 -3.7 -3.6 0.5 0.0 -3.8 -3.8 -4.0 -4.3 -4.2 -4.2 -4.5 -4.9 -3.6 -3.9 -4.6 4.2 -4.5 -4.2 -4.6
Crohns Disease (2012) 0.7 1.1 3.6 -0.1 0.6 1.9 1.2 0.6 1.9 0.7 1.0 1.2 0.9 1.5 1.0 0.9 0.7 0.8 0.9 0.9 1.2 0.8 -0.8 0.8 1.2 1.1
Mean Putamen Volume 1.7 1.9 3.5 -1.0 -1.7 -0.9 -1.2 -1.6 -0.8 -0.9 1.1 -1.2 -1.4 -1.4 -1.9 -1.6 -1.6 -1.5 -1.6 -1.3 -1.1 -1.5 1.7 -1.5 -1.2 -1.5
Fasting Glucose 0.3 0.4 1.3 -1.1 0.1 0.3 -0.3 -0.4 0.3 1.1 -0.7 -0.4 -0.7 -0.2 -0.6 -0.7 -0.9 -0.3 -0.6 -0.6 -0.5 -0.6 1.0 -0.5 -0.2 -0.4
HbA1C 1.0 1.1 7.5 -0.8 -1.6 0.4 -0.9 -0.6 -0.2 2.7 0.8 -1.3 -1.1 -0.6 -0.8 -1.1 -0.7 -0.9 -0.1 -1.4 -0.5 -1.1 0.9 -1.3 -0.7 -0.8
HDL Cholesterol 1.0 1.6 3.7 0.8 1.4 1.5 1.1 1.7 0.9 0.1 1.4 1.6 1.3 1.3 1.2 1.3 1.4 1.2 1.1 1.6 1.0 1.1 -1.9 1.2 0.9 1.2
LDL Cholesterol 0.3 0.5 1.4 -0.8 -0.9 -0.9 -0.3 -0.7 -0.2 -1.0 -0.7 -0.7 -0.6 0.2 -0.2 -0.6 -0.9 -0.8 -0.8 -0.8 -0.0 -0.6 1.2 -0.6 -0.3 -0.8
Lupus 2.1 3.2 8.5 -1.4 -0.8 -1.1 -2.0 -2.9 -1.4 -1.1 0.2 -1.6 -2.1 -1.8 -2.0 -2.0 -2.1 -1.8 -2.0 -2.1 -1.6 -1.9 2.2 -1.8 -1.7 -1.9
Neuroticism (2016) 0.1 0.2 1.2 -0.1 0.0 0.6 0.1 0.7 0.1 -1.1 1.0 0.5 -0.0 0.6 0.3 0.0 0.2 0.2 0.2 0.0 0.1 0.1 -0.7 0.1 0.2 0.3
Primary Biliary Cirrhosis 0.1 0.1 1.0 1.0 -0.5 -0.5 -0.0 0.1 -0.3 0.4 -0.4 -0.1 0.1 -0.2 -0.1 0.0 -0.0 -0.1 0.6 -0.2 0.2 0.0 0.2 0.0 0.2 0.0
Rheumatoid Arthritis 0.7 1.0 5.2 -0.8 -2.3 0.8 -0.5 -1.0 0.3 -0.8 0.7 -1.0 -0.9 -0.6 -1.0 -1.0 -1.0 -0.9 -0.1 -0.9 -0.4 -1.3 1.6 -1.3 -0.4 -0.6
Schizophrenia (2014) 2.7 6.1 13.6 -3.0 -2.3 -1.5 -2.3 -3.7 -0.7 -1.5 0.0 -2.5 -3.1 -1.1 -2.4 -3.0 -3.1 -2.9 -2.3 -3.3 -1.0 -2.7 3.6 -2.6 -1.3 -2.2
Triglycerides 2.2 3.5 5.6 -2.0 -1.5 -1.9 -1.8 -2.0 -1.3 0.6 -1.6 -2.3 -1.9 -1.8 -1.9 -1.9 -2.0 -2.0 -1.5 -2.3 -1.5 -2.1 2.4 -2.3 -1.7 -2.1
Type 2 Diabetes (T2D) (2012) 1.7 2.0 5.7 -1.2 -0.3 -1.5 -1.4 -1.3 -1.0 0.9 -1.7 -0.6 -1.3 -1.5 -1.8 -1.4 -1.6 -1.6 -0.8 -1.5 -1.4 -1.6 2.4 -1.5 -1.3 -1.4
Ulcerative Colitis 0.1 0.1 0.5 -0.0 -0.2 0.6 0.5 0.2 0.7 0.2 0.0 0.4 0.4 0.3 0.2 0.2 -0.0 0.0 -0.0 0.5 0.1 -0.1 -0.1 -0.1 0.2 0.2
Blood Eosinophil Count 1.9 14.4 21.1 2.4 4.1 4.6 4.4 3.1 4.6 -0.0 -0.4 3.3 3.9 4.3 4.3 4.0 3.8 3.9 3.8 4.5 4.2 3.8 -3.7 3.8 4.2 4.0
Blood Platelet Count 1.7 19.3 28.8 4.6 2.1 4.3 5.1 4.3 5.4 1.1 0.0 4.0 4.5 4.0 4.7 4.8 4.9 5.0 4.3 4.8 4.3 5.1 -4.9 4.9 4.5 4.8
Blood Red Count 1.4 13.4 27.0 2.1 3.9 1.2 3.0 3.3 0.2 -0.8 -1.7 4.3 4.3 3.6 4.3 4.5 4.2 4.4 3.0 4.2 3.8 4.2 -5.2 4.5 3.6 4.1
Blood White Count 0.1 0.6 5.5 0.3 1.4 0.2 -0.3 -0.1 -1.3 0.6 -2.4 -1.1 0.5 -0.4 0.5 0.5 0.3 0.4 -0.7 0.7 0.4 0.4 -0.8 0.5 -0.2 -0.1
Heel T-Score 1.5 11.7 27.4 -1.9 -1.1 -4.4 -4.1 -1.6 -5.2 0.4 -5.2 -3.3 -3.2 -3.9 -3.4 -3.2 -2.9 -3.1 -3.2 -3.0 -4.4 -3.3 2.9 -3.3 -3.9 -3.5
BMI 1.4 7.9 16.2 -3.5 -1.7 -4.0 -3.0 -2.1 -3.6 -0.3 -2.5 -3.3 -2.7 -3.1 -3.0 -2.8 -2.6 -2.8 -2.1 -3.0 -2.5 -2.8 3.1 -2.8 -2.4 -3.0
Height 2.6 49.5 80.1 -0.1 -0.3 -7.3 -7.3 -5.4 -6.2 5.8 -3.5 -8.9 -6.7 -8.9 -7.8 -7.3 -7.5 -8.1 -7.2 -5.9 -8.6 -7.9 6.9 -8.0 -8.6 -8.3
Waist Hip Ratio (WHR) 1.7 7.7 11.4 -2.2 -2.7 -1.5 -3.0 -2.5 -2.3 0.0 1.2 -3.2 -3.0 -3.0 -3.0 -3.1 -3.2 -3.2 -3.4 -2.8 -2.9 -3.1 2.6 -3.1 -3.2 -3.0
Systolic Blood Pressure 2.6 12.9 22.1 -2.9 -3.6 -0.6 -3.9 -3.4 -2.5 -0.6 2.7 -2.7 -4.2 -3.5 -4.1 -4.2 -4.0 -3.9 -3.6 -4.7 -3.7 -4.2 3.9 -4.2 -3.7 -4.2
Smoking Status 3.3 7.8 14.7 -3.2 -1.1 -1.3 -3.0 -2.6 -1.4 0.4 0.7 -2.8 -3.3 -2.9 -3.5 -3.5 -3.2 -3.1 -3.1 -3.0 -2.2 -3.4 3.8 -3.5 -2.5 -3.1
Allergy or Eczema 0.8 2.2 6.4 1.6 0.2 2.5 2.0 0.9 2.4 0.3 1.1 1.1 1.6 0.9 1.3 1.5 1.2 1.4 1.6 1.1 1.7 1.2 -1.1 1.4 1.7 1.7
Cardiovascular Disease 0.2 0.8 2.5 -0.6 -0.2 0.4 -1.0 0.3 -1.2 -0.7 1.1 0.6 -0.7 -1.5 -1.3 -0.8 -0.6 -0.7 -0.3 -0.8 -1.6 -0.9 0.3 -0.9 -1.1 -1.1
Hypothyroidism (self reported) 0.6 1.4 6.0 0.5 1.8 2.5 1.1 1.6 1.3 0.4 -0.4 0.7 0.9 1.0 0.9 0.9 1.3 1.2 1.0 0.7 1.5 1.0 -0.8 1.0 1.4 1.0
Respiratory disease 0.5 1.0 8.0 0.1 -0.5 2.0 1.4 0.0 2.8 1.2 0.7 0.3 0.7 1.0 0.9 0.6 0.3 0.4 0.4 0.7 1.1 0.6 -0.4 0.4 1.0 0.8
Type 2 Diabetes (T2D) (2018) 3.0 5.5 8.4 -2.3 -2.0 -2.1 -2.7 -2.2 -2.6 -0.2 -1.5 -1.8 -2.6 -2.2 -2.9 -2.6 -2.3 -2.3 -2.8 -2.9 -1.9 -2.5 2.9 -2.5 -2.0 -2.5
Lung FEV1/FVC ratio 0.7 3.7 10.0 0.8 -0.2 -1.7 -2.4 -1.2 -3.2 1.8 -0.7 -2.1 -1.7 -2.5 -2.3 -1.9 -1.9 -1.9 -1.0 -1.7 -1.8 -2.2 2.3 -2.2 -1.9 -2.0
Lung FVC 0.2 1.0 7.2 2.7 1.1 -0.1 0.4 1.7 -0.3 0.2 -1.1 0.3 0.9 0.3 0.9 0.9 1.1 1.0 0.7 1.3 0.1 0.9 -1.1 0.9 0.0 0.6
Neuroticism 0.3 0.8 6.5 -1.6 -1.8 0.8 -0.3 -0.1 0.3 -1.4 2.5 0.3 -0.6 -0.3 -0.5 -0.6 -0.4 -0.4 -0.7 -0.5 -0.9 -0.4 -0.0 -0.4 -0.5 -0.3
Chronotype (morning person) 0.2 0.4 2.5 -1.4 -0.8 0.5 -0.2 -1.6 -0.5 0.2 -0.0 -0.3 0.1 -0.6 -0.5 -0.1 -0.6 -0.2 -0.5 0.2 -0.9 -0.3 0.0 -0.3 -1.0 -0.4
Hair Pigment 26.2 746.4 3158.4 -18.9 -14.9 34.8 20.7 22.2 -2.6 -56.2 43.2 33.1 25.4 5.8 13.7 25.8 28.3 26.3 23.4 30.9 -5.3 26.5 -44.4 25.7 5.2 20.3
Tanning 23.3 284.4 1528.8 10.2 -6.4 -5.0 -10.5 -17.2 15.5 39.1 10.8 -21.8 -16.6 -2.3 -8.8 -17.3 -19.0 -17.7 -13.2 -22.4 7.4 -18.1 27.5 -18.0 0.0 -11.5
Hand grip strength (left) 0.9 2.3 6.8 0.7 0.9 -1.8 -2.0 -0.2 -2.6 1.1 -0.5 -1.1 -1.3 -2.6 -1.8 -1.2 -0.9 -1.1 -1.2 -1.2 -2.5 -1.1 0.4 -1.2 -2.2 -1.7
Number of treatments/medications taken 0.5 0.9 7.6 -2.8 -0.6 1.4 0.0 -0.0 0.7 -1.0 2.4 0.8 -0.3 0.1 -0.7 -0.5 -0.3 -0.3 -0.2 -0.0 -0.4 -0.7 0.5 -0.7 -0.1 -0.4
Average weekly spirits intake 1.3 1.6 3.2 -0.4 -1.1 -1.8 -1.5 -1.1 -1.4 0.2 1.4 -1.0 -1.4 -1.4 -1.4 -1.4 -1.4 -1.4 -1.1 -1.3 -1.4 -1.2 0.8 -1.2 -1.4 -1.3
Sensitivity / hurt feelings 1.7 2.9 9.4 -3.1 -1.9 -0.1 -1.8 -1.4 -2.1 -1.6 -0.0 -0.7 -1.5 -1.8 -2.0 -1.6 -1.6 -1.4 -1.7 -1.6 -2.3 -1.6 1.2 -1.6 -2.0 -1.7
Frequency of depressed mood in last 2 weeks 0.2 0.3 2.0 0.6 -0.9 0.5 0.4 1.0 0.4 0.7 1.4 0.5 0.6 0.1 0.2 0.4 0.5 0.5 0.3 0.5 0.2 0.3 -0.6 0.3 0.2 0.5
Hearing difficulty/problems: Yes 0.4 0.7 7.0 -0.7 -0.6 1.2 0.5 1.4 1.0 2.6 -0.4 0.4 0.3 0.7 0.2 0.2 0.5 0.3 0.4 0.5 0.6 0.0 0.5 -0.1 0.7 0.3
Relative age of first facial hair 1.0 2.0 7.1 -2.5 -2.3 0.6 -1.1 -1.1 -2.0 -2.7 0.6 -0.8 -0.8 -1.4 -1.4 -0.9 -1.1 -1.1 -0.1 -0.2 -2.2 -1.1 0.1 -1.2 -1.8 -1.1
Other serious medical condition/disability diagnosed by doctor 3.3 4.2 19.9 -4.5 -1.4 -0.2 -1.9 -2.1 -1.5 -3.0 -0.0 -1.2 -2.1 -0.8 -1.8 -2.1 -2.2 -2.3 -2.0 -1.5 -1.7 -2.3 2.2 -2.3 -1.9 -2.0
Ever used hormone-replacement therapy (HRT) 1.5 1.9 3.5 -1.3 -1.5 -0.2 -1.3 -1.1 -1.5 0.5 1.6 -1.1 -1.0 -1.7 -1.9 -1.3 -1.5 -1.4 -1.5 -0.7 -1.7 -1.9 1.3 -1.7 -1.5 -1.4
Ever had hysterectomy (womb removed) 0.9 1.0 6.2 -0.3 0.1 2.1 0.9 0.6 0.9 -1.7 2.5 0.5 0.8 0.9 0.8 0.7 0.6 0.6 0.4 0.7 0.7 0.5 -0.6 0.6 0.8 0.7
Systolic blood pressure, automated reading 1.9 5.6 8.8 -1.7 -1.7 -1.2 -2.3 -2.6 -1.4 -1.1 2.5 -2.2 -2.6 -2.3 -2.7 -2.7 -2.6 -2.7 -2.5 -3.0 -2.1 -2.8 2.4 -2.7 -2.4 -2.8
Eye problems/disorders: Diabetes related eye disease 2.9 3.2 5.8 -0.9 0.1 -2.4 -2.2 -1.8 -2.1 0.2 -1.8 -1.8 -2.2 -1.2 -1.5 -2.0 -1.9 -1.9 -2.0 -2.1 -1.5 -1.9 2.0 -1.8 -1.7 -1.8
Angina 1.6 2.1 6.4 -2.5 -1.2 -0.4 -1.6 -1.6 -1.1 -1.8 0.4 -0.8 -1.8 -0.9 -1.7 -1.7 -1.3 -1.4 -1.6 -1.8 -0.6 -1.4 1.6 -1.4 -0.7 -1.3
Medication for hormone replacement therapy 1.4 1.6 3.1 -0.0 -1.6 0.0 -1.4 -0.7 -1.0 0.3 0.7 -1.3 -1.4 -1.4 -1.5 -1.6 -1.4 -1.4 -0.7 -1.7 -1.3 -1.7 1.6 -1.8 -1.1 -1.3
Vitamin and mineral supplements 0.5 0.7 3.6 0.3 1.5 0.7 0.3 0.5 -0.4 0.5 -1.9 0.9 0.8 0.1 0.7 0.9 0.8 0.9 1.1 1.2 -0.1 0.7 -0.9 0.8 0.1 0.6
Supplements: Zinc 0.8 0.9 3.4 0.1 -0.9 -1.0 -0.7 -0.2 0.6 1.0 1.8 -0.4 -1.3 -0.1 -0.7 -1.2 -0.7 -1.0 -0.8 -1.9 0.1 -0.9 1.4 -0.9 -0.1 -0.8
Medication: Co-codamol 0.5 0.6 2.4 -0.5 -1.6 -0.6 -0.6 -1.0 0.3 1.2 0.8 -0.4 -0.8 -0.5 -0.7 -0.8 -0.8 -0.6 -0.9 -0.8 -0.5 -0.5 1.0 -0.6 -0.6 -0.8
Medication: Metformin 3.3 4.6 9.7 -1.5 -0.9 -2.9 -2.3 -2.1 -3.1 -0.8 -2.7 -1.7 -2.0 -2.5 -2.5 -2.0 -1.9 -1.8 -2.7 -2.0 -2.2 -1.9 1.9 -1.9 -2.2 -2.3
Diabetes (father) 1.0 1.2 4.1 -2.0 0.6 -2.0 -0.8 -0.9 -0.8 -1.4 -1.3 -0.3 -1.0 -0.0 -1.0 -1.0 -0.9 -1.1 -0.7 -0.9 -0.6 -0.9 1.7 -0.9 -0.7 -1.2
Diabetes (mother) 0.7 0.9 3.2 -1.1 -0.4 -1.1 -0.9 -1.1 -0.2 0.6 -0.3 -0.3 -1.2 -0.3 -1.2 -1.2 -0.9 -0.9 -0.9 -1.3 -0.0 -1.0 1.8 -1.1 -0.1 -0.6
Severe depression (siblings) 0.3 0.3 0.9 -0.9 -0.8 -0.1 -0.6 0.1 -0.2 -0.7 1.0 -0.3 -0.7 -0.1 -0.6 -0.6 -0.2 -0.5 -0.4 -0.8 -0.0 -0.4 0.7 -0.4 -0.0 -0.4
Pack years adult smoking proportion 0.4 0.6 2.0 -1.3 -0.9 -0.5 -1.0 -0.5 -0.5 -0.3 -0.5 0.1 -1.1 0.4 -0.6 -1.0 -0.9 -0.9 -0.7 -1.0 -0.1 -0.9 1.4 -1.0 -0.3 -0.8
Impedance of leg (right) 1.7 8.3 17.6 4.2 2.7 2.5 3.6 2.2 4.0 0.5 -0.7 2.8 3.0 3.4 3.0 3.0 2.6 3.0 2.8 3.2 3.2 2.6 -1.9 2.6 3.0 3.1
Leg fat-free mass (left) 6.6 35.1 54.9 -3.8 -3.7 -5.6 -6.6 -4.7 -6.2 2.2 -2.1 -6.9 -6.1 -7.4 -6.8 -6.4 -6.2 -6.6 -5.6 -6.4 -6.8 -6.4 6.0 -6.5 -6.5 -6.8
Trunk fat percentage 1.3 5.1 17.8 -0.0 -0.3 -4.2 -1.8 -1.7 -1.1 2.1 -2.8 -3.4 -2.0 -2.1 -2.2 -2.3 -2.3 -2.5 -1.2 -2.5 -1.1 -2.5 3.2 -2.3 -1.2 -2.1
Hand grip strength (right) 2.6 7.2 20.3 -0.8 -0.3 -3.0 -3.5 -1.2 -4.5 1.1 -2.1 -2.2 -2.5 -3.7 -2.9 -2.5 -2.2 -2.5 -2.6 -2.5 -3.9 -2.5 1.5 -2.4 -3.6 -3.0
Townsend deprivation index at recruitment 0.6 0.9 2.8 -0.1 -1.0 -0.9 -0.9 -1.4 -0.5 -0.1 0.6 -1.7 -1.0 -0.9 -0.6 -1.0 -1.1 -0.9 -1.1 -1.2 -0.2 -1.0 1.0 -1.0 -0.4 -0.9
Current tobacco smoking 1.4 2.3 5.6 -1.6 -0.6 -1.7 -1.6 -0.9 -0.8 1.4 -0.7 -1.1 -1.8 -1.2 -1.7 -1.8 -1.6 -1.6 -1.6 -1.5 -1.3 -1.7 2.4 -1.9 -1.4 -1.8
Average weekly fortified wine intake 1.0 1.1 2.9 0.2 0.8 1.1 0.8 0.4 0.9 -1.1 1.6 1.7 0.7 1.0 1.0 1.0 1.2 1.4 0.4 1.0 0.7 1.5 -1.5 1.4 0.8 0.7
Maternal smoking around birth 1.6 2.4 4.5 -0.8 -0.7 -2.1 -1.4 -1.3 -1.6 1.0 -1.5 -1.8 -1.2 -1.6 -1.6 -1.4 -1.8 -1.8 -0.8 -1.3 -1.4 -1.9 2.0 -1.9 -1.6 -1.7
Fed-up feelings 0.1 0.3 2.2 -1.5 -0.2 -0.2 -0.3 -0.4 -0.5 0.3 0.7 -0.8 -0.1 -0.5 -0.3 -0.2 -0.4 -0.3 -0.6 0.1 -0.5 -0.3 -0.1 -0.4 -0.3 -0.6
Frequency of unenthusiasm / disinterest in last 2 weeks 0.2 0.3 2.6 0.6 -0.6 -0.3 0.6 0.6 0.4 0.4 1.6 -0.2 0.7 -0.4 -0.1 0.4 0.3 0.2 0.2 0.7 0.2 0.1 -0.3 0.1 0.1 0.2
Relative age voice broke 0.4 0.6 5.3 -0.2 -1.4 0.6 0.5 0.3 -0.0 -0.6 2.3 -0.2 0.6 -0.5 -0.1 0.5 0.4 0.4 1.3 1.0 -0.2 0.3 -1.0 0.2 0.1 0.5
Taking other prescription medications 0.7 1.1 12.4 -3.5 -0.7 0.8 -0.2 -1.0 0.5 -0.6 1.2 -0.4 -0.6 -0.2 -1.0 -0.8 -0.7 -0.6 -0.6 -0.4 -0.1 -1.1 1.4 -1.0 -0.1 -0.5
Age when periods started (menarche) 1.0 2.3 8.2 -0.8 -0.9 -2.9 -1.5 -2.5 -1.9 -0.6 -2.0 -1.5 -1.2 -1.2 -1.1 -1.1 -1.6 -1.3 -2.0 -1.4 -1.5 -1.0 1.0 -0.9 -1.6 -1.5
Bilateral oophorectomy (both ovaries removed) 0.1 0.1 1.4 -0.2 0.1 0.4 0.1 0.5 -0.1 0.2 1.2 0.2 0.3 -0.4 -0.0 0.2 0.3 0.2 -0.0 0.3 -0.3 0.1 -0.3 0.0 -0.2 0.0
Heel bone mineral density (BMD) T-score, automated (left) 1.0 2.2 4.1 -1.3 0.4 -2.0 -1.6 -0.8 -1.9 -1.0 -1.5 -1.8 -1.4 -1.9 -1.5 -1.4 -1.1 -1.3 -1.3 -1.4 -1.8 -1.2 1.7 -1.3 -1.7 -1.8
Tinnitus: Yes, but not now, but have in the past 0.4 0.5 1.8 0.4 -0.5 -0.7 -0.9 0.0 -1.3 -0.1 -0.3 -0.3 -0.7 -0.9 -0.8 -0.7 -0.5 -0.5 -0.6 -0.6 -0.6 -0.7 1.2 -0.7 -0.4 -0.4
Qualifications: CSEs or equivalent 0.3 0.4 2.5 0.6 -0.8 -1.5 -0.2 -0.2 -0.3 1.6 -0.5 -0.8 0.0 -0.5 0.2 0.0 -0.2 -0.2 -0.8 -0.2 0.0 0.2 0.2 0.1 -0.1 -0.2
Serious illness, injury or assault to yourself 0.3 0.4 4.7 -2.2 0.5 0.1 -0.4 -0.5 -0.8 -1.4 -0.1 0.4 -0.2 0.3 -0.5 -0.2 -0.0 -0.0 -0.5 0.4 0.4 -0.0 0.5 -0.0 0.1 -0.0
High blood pressure 0.5 1.5 5.6 -1.4 0.1 1.0 -1.1 0.1 -1.5 -1.5 1.5 0.1 -0.6 -2.1 -1.4 -0.8 -0.7 -0.8 -0.8 -0.4 -2.4 -1.0 -0.2 -0.9 -1.8 -1.5
Hayfever, allergic rhinitis or eczema 0.7 1.5 3.1 1.8 -0.3 1.8 1.7 1.0 1.8 0.7 0.7 1.0 1.5 0.6 1.0 1.3 1.1 1.2 1.3 1.2 1.4 1.0 -0.9 1.1 1.5 1.3
Multivitamins +/- minerals 0.3 0.4 2.2 0.4 -0.5 0.2 0.7 0.4 1.4 1.2 1.5 0.2 0.2 0.8 0.3 0.1 0.2 0.1 0.2 -0.1 0.7 0.2 0.0 0.1 0.7 0.4
Stomach or abdominal pain in last month 0.9 1.2 5.4 -1.1 0.4 0.4 1.2 -0.5 1.3 -1.6 -0.5 0.7 0.7 2.3 1.1 0.7 0.4 0.6 0.9 1.0 2.0 0.8 -0.1 0.9 1.6 0.9
Supplements: Glucosamine 0.3 0.4 5.3 -0.4 -0.7 -0.4 -0.1 -0.8 0.5 0.0 2.3 -0.6 -0.3 -0.2 -0.2 -0.4 -0.6 -0.6 -0.2 -0.2 -0.3 -0.6 0.6 -0.5 -0.3 -0.2
Diverticular disease/diverticulitis (self-reported) 0.6 0.8 2.4 -0.4 0.0 -0.7 -0.7 -1.1 -0.7 -1.0 -0.4 -1.6 -0.9 -1.1 -0.9 -0.9 -0.9 -0.9 -0.7 -0.8 -0.5 -0.9 1.1 -0.9 -0.8 -1.0
Medication: Atenolol 1.3 1.6 6.4 -2.2 0.1 1.7 -1.3 -0.3 -1.5 -1.8 2.5 -0.4 -0.8 -1.5 -1.3 -0.9 -0.6 -0.6 -1.0 -0.6 -1.7 -0.9 -0.2 -1.0 -1.5 -1.1
Medication: Levothyroxine sodium 0.2 0.4 5.1 -0.7 2.3 0.4 0.3 0.4 0.5 0.8 -0.6 0.2 0.3 0.4 0.3 0.3 0.5 0.4 -0.0 0.4 0.6 0.3 0.1 0.3 0.5 0.2
Sitting height 2.8 20.1 35.3 -1.2 -1.9 -3.5 -4.8 -2.6 -4.3 2.1 -1.5 -5.5 -4.5 -5.9 -5.4 -4.9 -4.6 -5.2 -4.5 -4.4 -5.6 -5.2 4.6 -5.2 -5.4 -5.4
Chronic bronchitis/emphysema (father) 0.1 0.1 0.4 -0.4 -0.3 0.2 0.2 -0.6 0.3 0.5 0.0 -0.1 0.1 0.3 -0.1 -0.0 -0.2 -0.1 0.2 0.1 0.6 -0.2 0.5 -0.1 0.6 0.2
High blood pressure (mother) 0.3 0.4 2.0 -0.0 1.3 0.5 -0.2 0.5 -0.9 -1.4 -0.8 0.1 -0.0 -0.9 0.0 0.1 0.1 0.1 -0.3 -0.1 -1.3 -0.0 -0.4 0.1 -1.1 -0.7
Body mass index (BMI) 2.2 9.4 15.1 -3.3 -2.1 -3.9 -3.2 -2.3 -3.2 0.5 -1.7 -3.7 -3.1 -3.5 -3.4 -3.3 -3.0 -3.4 -2.4 -3.5 -2.7 -3.3 3.5 -3.2 -2.7 -3.4
Impedance of leg (left) 2.7 13.1 20.6 4.5 3.8 2.9 4.4 2.8 4.5 0.3 -1.1 3.5 3.9 4.2 3.9 3.8 3.5 3.8 3.4 4.2 4.1 3.4 -2.8 3.5 3.8 3.9
Leg predicted mass (left) 6.6 34.7 54.0 -3.8 -3.6 -5.6 -6.6 -4.7 -6.2 2.3 -2.1 -6.8 -6.1 -7.3 -6.7 -6.3 -6.1 -6.5 -5.6 -6.3 -6.8 -6.4 5.9 -6.5 -6.5 -6.8
Trunk fat mass 3.2 13.5 26.8 -1.5 -1.1 -5.2 -3.6 -2.8 -2.9 2.3 -2.8 -5.1 -3.6 -4.2 -4.0 -3.9 -3.9 -4.2 -2.9 -4.0 -3.2 -4.2 4.5 -4.0 -3.3 -4.1
Waist circumference 5.4 19.7 28.8 -3.5 -3.0 -4.7 -4.7 -3.4 -4.0 1.9 -1.6 -5.4 -4.6 -5.1 -5.1 -4.9 -4.8 -5.1 -4.1 -4.9 -4.5 -5.1 5.0 -5.0 -4.3 -4.8
Number of incorrect matches in round 0.7 1.2 6.2 0.5 0.6 1.2 1.2 -0.9 2.5 0.3 2.2 -0.2 0.6 1.5 1.1 0.6 0.3 0.5 1.1 0.3 1.5 0.8 -0.3 0.8 1.0 0.9
Past tobacco smoking 4.5 8.3 13.1 2.9 1.8 0.5 3.1 2.6 1.8 -0.4 -1.5 3.2 3.3 3.1 3.5 3.5 3.2 3.2 2.9 3.2 2.6 3.6 -3.4 3.6 2.7 3.1
Alcohol usually taken with meals 0.4 0.6 1.3 -0.4 0.1 -1.0 -0.7 -1.0 -0.5 -0.8 -0.1 -0.9 -0.8 -1.0 -0.8 -0.7 -0.9 -0.9 -0.8 -0.8 -0.9 -0.7 0.5 -0.7 -0.9 -1.1
Nervous feelings 0.5 0.9 4.1 -0.5 -1.7 0.2 -0.7 -0.7 -0.3 -2.0 1.7 -0.1 -0.8 -0.9 -1.1 -0.9 -0.8 -0.8 -0.9 -0.9 -1.1 -0.7 0.5 -0.8 -0.8 -0.8
Frequency of tenseness / restlessness in last 2 weeks 0.9 1.3 5.6 -0.8 -2.4 -0.5 -1.0 -0.3 -0.8 -0.6 1.8 -1.2 -1.1 -0.8 -1.2 -1.2 -1.2 -1.3 -0.7 -1.2 -0.7 -1.4 1.3 -1.3 -1.0 -1.0
Hearing difficulty/problems with background noise 0.5 0.8 1.9 -0.5 -1.0 0.8 -0.4 -0.2 0.6 1.4 1.1 -0.6 -0.7 -0.3 -0.9 -0.9 -0.9 -1.1 0.0 -0.6 -0.5 -1.4 1.3 -1.4 -0.6 -0.9
Hair/balding pattern: Pattern 2 0.2 0.2 1.3 -0.9 0.3 0.4 -0.2 -0.7 -0.7 -0.8 -0.0 -1.1 0.0 -0.4 -0.2 0.0 -0.2 -0.1 -0.2 0.2 -0.0 0.0 -0.2 0.1 -0.0 0.2
Had menopause 1.9 2.4 13.4 -1.2 -1.5 0.2 -1.4 -1.3 -0.6 -0.7 3.7 -1.0 -1.5 -0.9 -1.4 -1.6 -1.6 -1.8 -2.0 -1.2 -1.2 -1.8 0.9 -1.7 -1.5 -1.5
Had other major operations 1.3 1.6 3.2 0.8 1.4 0.9 1.4 1.2 1.6 -1.1 -0.3 1.4 1.0 1.5 1.3 1.2 1.4 1.4 1.2 1.0 1.7 1.4 -0.4 1.4 1.8 1.5
Forced vital capacity (FVC) 2.1 7.9 16.8 1.5 -0.5 -3.1 -3.1 -1.3 -3.5 2.1 -2.1 -3.5 -2.4 -4.0 -3.0 -2.6 -2.6 -2.8 -2.7 -1.9 -4.1 -2.8 2.2 -2.8 -3.8 -3.2
Heel bone mineral density (BMD) T-score, automated (right) 0.5 1.1 3.7 0.1 0.4 -1.2 -1.0 -0.3 -1.5 0.2 -1.9 -1.8 -0.8 -1.7 -1.2 -0.8 -0.7 -0.8 -0.5 -0.6 -1.3 -0.8 1.2 -0.8 -1.2 -1.2
Ever unenthusiastic/disinterested for a whole week 1.6 2.0 5.2 -0.3 -2.3 -0.9 -1.5 -1.4 -1.2 -1.4 1.1 -0.9 -1.4 -1.8 -1.6 -1.4 -1.2 -1.2 -1.3 -1.8 -1.3 -1.2 1.6 -1.3 -1.5 -1.4
Qualifications: None of the above 0.5 1.0 2.2 -1.5 -1.3 -0.8 -0.8 -1.0 -0.5 -1.5 1.1 -1.2 -1.0 -0.6 -0.9 -1.1 -1.0 -1.0 -1.2 -1.0 -0.3 -1.2 1.1 -1.0 -0.6 -0.8
Financial difficulties in last 2 years 0.3 0.4 1.1 -0.4 -0.7 0.9 0.6 0.5 -0.1 -0.2 1.1 0.6 1.0 0.2 0.4 0.7 0.4 0.5 0.9 0.7 0.6 0.2 -0.2 0.3 0.8 0.9
Mouth/teeth dental problems 0.3 0.4 1.3 0.8 0.6 -1.0 0.6 0.3 0.5 0.7 0.3 0.3 0.8 0.6 0.7 0.8 0.5 0.4 0.2 1.1 0.3 0.6 -1.0 0.7 -0.1 0.6
Heart attack 0.7 1.0 1.9 -1.3 0.1 -0.4 -1.1 -1.2 -0.7 -0.5 0.9 -1.0 -1.1 -1.1 -1.4 -1.1 -0.9 -0.9 -1.1 -0.9 -0.6 -0.9 1.4 -1.0 -0.6 -0.9
Allergy 0.8 1.9 5.3 -1.2 -0.9 -1.8 -2.1 -0.7 -2.3 -0.1 0.7 -1.0 -1.7 -1.0 -1.4 -1.5 -1.1 -1.3 -1.5 -1.6 -1.7 -1.3 0.6 -1.2 -1.7 -1.5
Pain all over the body in last month 0.2 0.3 1.4 -0.1 0.1 0.1 0.5 0.9 0.9 -0.6 0.4 0.3 0.1 0.6 0.0 -0.1 -0.0 -0.4 0.4 0.0 0.7 -0.4 1.2 -0.3 0.7 0.2
Diabetes (self-reported) 5.7 8.8 12.9 -3.6 -1.5 -2.8 -3.4 -2.9 -3.3 0.3 -2.7 -2.4 -3.3 -2.7 -3.4 -3.3 -3.0 -2.9 -3.5 -3.2 -2.8 -3.0 3.2 -3.1 -2.8 -3.1
Hayfever/allergic rhinitis (self-reported) 0.5 0.7 2.6 1.1 -1.6 0.4 1.3 0.2 1.2 0.6 1.1 -0.0 1.1 0.5 0.6 0.9 0.4 0.4 0.9 0.5 0.7 0.3 -0.4 0.4 1.0 0.7
Medication: Ramipril 1.7 2.2 7.3 -2.7 -0.6 -0.7 -1.8 -0.7 -1.2 -0.5 0.0 -0.7 -1.8 -0.9 -1.5 -1.8 -1.4 -1.7 -1.8 -1.8 -1.5 -1.8 1.7 -1.8 -1.3 -1.7
Medication: Simvastatin 0.4 0.7 2.3 -1.5 -0.4 -0.5 -0.9 0.0 -1.1 -1.2 -0.3 -0.2 -0.8 -0.5 -1.1 -0.9 -0.5 -0.6 -0.4 -0.8 -0.3 -0.9 1.3 -1.0 -0.3 -0.8
Fluid intelligence score 0.4 0.8 6.2 -0.5 2.2 -0.1 -0.3 0.7 -0.7 2.5 -1.6 0.6 0.1 -0.4 -0.2 0.1 0.2 0.1 0.2 0.6 -0.9 0.1 -0.4 0.0 -0.7 -0.4
Illnesses of siblings 3.0 4.2 6.7 2.4 1.7 0.2 2.2 1.6 2.4 1.6 -0.8 1.8 1.9 2.5 2.5 2.1 2.0 2.2 1.7 1.9 2.6 2.5 -1.8 2.4 2.6 2.4
Neuroticism score 0.5 1.1 3.1 -1.8 -1.0 -0.9 -1.1 -0.4 -0.8 -0.4 0.9 -0.7 -1.1 -1.0 -1.1 -1.2 -1.0 -1.1 -1.2 -1.0 -1.6 -1.0 0.5 -1.0 -1.3 -1.2
Weight 5.2 25.4 38.9 -3.2 -2.3 -5.5 -5.4 -3.7 -4.9 2.5 -2.6 -6.2 -5.0 -6.2 -5.8 -5.4 -5.2 -5.7 -4.5 -5.3 -5.4 -5.6 5.5 -5.6 -5.2 -5.8
Impedance of arm (right) 1.0 4.7 17.6 4.2 0.9 1.3 2.6 0.5 4.2 1.6 1.8 1.1 1.7 2.9 2.4 1.7 1.2 1.5 1.8 1.8 3.1 1.6 -0.7 1.6 2.7 2.2
Arm fat percentage (right) 1.9 7.3 14.9 -1.7 -2.1 -3.8 -2.5 -2.3 -1.6 1.1 -1.2 -3.9 -2.9 -2.7 -2.9 -3.0 -3.0 -3.2 -1.9 -3.3 -1.8 -3.1 3.8 -3.1 -1.9 -2.9
Trunk fat-free mass 6.2 35.7 60.8 -4.5 -3.0 -4.5 -6.7 -4.3 -6.3 2.3 -1.7 -6.5 -6.1 -7.8 -7.1 -6.4 -6.0 -6.5 -6.1 -6.0 -7.6 -6.5 5.7 -6.6 -7.2 -7.2
Hip circumference 2.3 10.0 16.6 -1.9 -1.3 -3.4 -3.3 -2.2 -2.9 2.2 -2.1 -4.0 -3.1 -4.1 -3.7 -3.4 -3.2 -3.6 -2.7 -3.4 -3.4 -3.5 3.6 -3.5 -3.1 -3.5
Time employed in main current job 1.0 1.2 4.1 -0.3 -1.2 -0.3 -0.8 -1.2 0.5 -1.1 2.0 -1.1 -1.4 -0.6 -1.3 -1.3 -1.0 -1.0 -1.1 -1.4 -0.4 -1.0 1.4 -1.1 -0.5 -0.9
Alcohol intake versus 10 years previously 0.4 0.6 5.0 -2.2 -0.9 -0.6 -0.4 -1.0 0.4 -0.7 0.0 -0.7 -0.7 0.3 -0.5 -0.7 -0.9 -0.8 -1.0 -0.1 -0.4 -0.6 1.0 -0.7 -0.6 -0.6
Father’s age at death 2.6 3.5 7.5 -2.7 -0.6 -1.8 -1.8 -2.0 -1.7 -1.7 -1.4 -2.2 -1.8 -1.5 -1.7 -1.8 -2.0 -2.2 -1.8 -1.6 -2.1 -2.0 1.8 -1.8 -2.3 -2.2
Worrier / anxious feelings 0.9 1.7 3.3 -1.7 -0.2 -1.2 -1.2 -0.9 -1.5 -1.8 -0.4 -0.9 -0.9 -1.6 -1.4 -1.1 -1.2 -1.3 -1.6 -0.7 -1.7 -1.4 1.0 -1.4 -1.8 -1.5
Frequency of tiredness / lethargy in last 2 weeks 0.1 0.2 1.0 -0.4 0.3 0.5 0.4 0.6 0.9 -0.2 0.3 -0.4 0.0 0.1 -0.5 -0.3 -0.1 -0.3 0.7 -0.2 0.4 -0.3 1.0 -0.5 0.3 -0.1
Falls in the last year 0.8 1.1 3.4 -1.1 -0.5 -1.8 -1.3 -1.1 -0.9 0.1 -0.5 -0.9 -1.4 -0.3 -0.7 -1.2 -1.1 -1.1 -1.5 -1.4 -0.8 -0.8 1.5 -0.8 -0.8 -0.9
Hair/balding pattern: Pattern 3 3.3 5.0 11.4 3.4 1.9 0.6 2.5 3.0 1.2 -0.1 -1.9 1.8 2.5 1.6 2.2 2.5 2.7 2.6 2.4 2.4 1.8 2.6 -2.4 2.5 2.1 2.2
Number of live births 2.6 3.6 8.9 -1.6 -1.5 -0.8 -1.9 -2.4 -0.6 1.5 2.3 -1.6 -2.1 -1.1 -1.7 -2.1 -2.2 -2.2 -3.0 -2.1 -1.3 -2.2 1.8 -2.1 -1.9 -2.1
Forced expiratory volume in 1-second (FEV1) 1.9 6.4 13.9 1.8 -0.2 -3.0 -2.9 -1.0 -3.7 2.4 -2.2 -3.1 -2.0 -3.7 -2.6 -2.2 -2.2 -2.3 -2.4 -1.6 -3.5 -2.2 1.9 -2.2 -3.4 -2.8
Pulse rate 0.8 1.4 2.9 1.2 1.0 -0.3 1.2 0.5 1.0 0.4 -0.8 1.3 1.1 1.3 1.6 1.3 1.4 1.5 1.0 0.7 1.3 1.7 -1.3 1.7 1.2 1.2
Happiness 3.5 4.3 10.3 2.3 0.1 3.2 2.4 2.7 2.3 -1.5 0.8 1.2 2.2 1.7 1.6 2.1 2.3 2.1 2.6 1.8 2.4 1.9 -1.6 1.9 2.5 2.1
Noisy workplace 0.3 0.4 2.7 -0.8 -0.6 1.6 0.2 -0.6 -0.1 -1.3 1.2 0.3 0.4 0.2 0.0 0.3 0.2 0.5 -0.2 0.3 0.3 0.3 -0.2 0.2 0.3 0.5
Qualifications: A levels/AS levels or equivalent 0.5 1.1 3.9 -0.5 -0.2 -0.8 -1.2 -0.0 -1.6 0.3 -0.7 -0.5 -0.8 -1.4 -1.1 -0.9 -0.8 -1.0 -0.7 -0.8 -2.0 -1.1 0.5 -1.2 -1.6 -1.4
Serious illness, injury or assault of a close relative in last 2 years 0.6 0.7 1.4 -0.7 -0.9 0.0 -1.0 -0.5 -0.5 -0.1 0.9 -0.9 -1.0 -0.5 -1.0 -1.0 -0.9 -1.0 -0.7 -1.1 -0.7 -0.9 1.2 -0.9 -0.6 -0.7
Mouth/teeth dental problems: Dentures 1.0 1.7 4.7 -2.1 -0.4 -0.8 -1.4 -0.8 -2.1 -2.2 -0.6 -0.4 -1.3 -1.1 -1.5 -1.3 -1.1 -1.0 -1.4 -1.1 -1.1 -1.3 1.4 -1.4 -1.0 -1.3
Asthma 0.3 0.6 2.9 -0.1 -1.4 0.9 0.3 -1.3 1.7 0.2 0.9 -0.8 -0.5 -0.1 -0.3 -0.7 -1.1 -0.9 -0.7 -0.4 0.1 -0.8 1.0 -0.9 0.0 -0.4
Medication: Ibuprofen (e.g. Nurofen) 0.2 0.3 1.1 0.1 0.0 1.0 -0.1 0.2 0.1 0.9 -0.4 -0.5 -0.3 -1.0 -0.8 -0.4 -0.3 -0.3 0.1 -0.5 -0.7 -0.5 0.7 -0.7 -0.2 -0.3
Medication: Cholesterol lowering 0.3 0.4 2.3 -1.2 0.8 -0.9 0.2 -0.1 -0.2 -1.5 -1.3 0.7 0.2 0.5 -0.1 0.1 0.2 0.4 0.2 0.4 0.3 0.3 0.3 0.2 0.5 0.2
Depression (self-reported) 0.4 0.4 3.8 -0.0 -1.0 -0.2 0.1 -0.4 0.8 1.9 1.7 -0.6 -0.0 -0.1 0.0 -0.1 -0.3 -0.4 0.3 -0.1 -0.4 -0.2 -0.2 -0.2 -0.4 -0.1
Medication: Lansoprazole 0.4 0.5 4.0 -0.6 -0.9 -1.2 0.2 0.1 0.2 -2.0 -1.3 -0.5 -0.3 0.4 -0.2 -0.4 -0.3 -0.5 -0.0 -0.4 0.3 -0.5 1.1 -0.4 0.4 -0.3
Prospective memory result 0.3 0.4 3.4 1.1 -1.8 0.2 -0.2 0.2 -0.3 1.3 0.9 0.1 0.0 -0.7 -0.2 0.0 0.1 0.3 -0.6 0.0 -0.4 0.1 -0.5 0.2 -0.0 0.4
Lung cancer (father) 0.6 0.8 2.7 0.3 -1.1 -0.4 -0.7 -0.7 -0.4 1.6 0.3 -1.1 -0.6 -1.3 -0.7 -0.7 -0.8 -0.8 -1.4 -1.2 -0.8 -0.8 0.2 -0.8 -0.8 -0.8
Illnesses of mother 0.3 0.3 1.2 0.2 -1.0 -1.0 -0.5 -0.6 -0.4 -0.4 0.2 -1.1 -0.6 -0.6 -0.6 -0.5 -0.4 -0.5 -0.2 -0.6 0.0 -0.5 0.5 -0.6 -0.2 -0.3
Forced expiratory volume in 1-second (FEV1), Best measure 1.0 3.3 7.2 1.9 -0.2 -2.1 -1.9 -0.4 -2.5 2.7 -1.8 -2.2 -1.2 -2.6 -1.8 -1.4 -1.4 -1.6 -1.5 -0.9 -2.5 -1.5 1.2 -1.6 -2.5 -2.0
Pulse wave Arterial Stiffness index 0.8 0.9 1.8 0.3 1.4 0.7 1.0 0.7 1.2 -0.2 -0.2 1.3 0.8 1.1 1.2 0.9 1.1 0.9 1.0 0.8 0.7 1.1 -0.8 1.2 0.8 1.0
Impedance of arm (left) 1.6 7.5 25.3 5.0 2.0 1.3 3.1 1.5 4.0 2.0 0.3 2.0 2.5 3.5 3.2 2.6 2.0 2.4 2.6 2.5 3.7 2.4 -1.6 2.4 3.3 3.0
Arm fat mass (right) 4.2 17.1 27.8 -3.0 -2.3 -4.9 -4.3 -3.3 -3.6 1.3 -1.9 -5.3 -4.3 -4.8 -4.7 -4.5 -4.3 -4.7 -3.5 -4.7 -3.9 -4.7 5.0 -4.6 -3.9 -4.7
Trunk predicted mass 6.4 36.7 61.3 -4.6 -3.0 -4.5 -6.8 -4.5 -6.4 2.2 -1.7 -6.6 -6.2 -7.8 -7.2 -6.5 -6.1 -6.6 -6.2 -6.0 -7.7 -6.6 5.8 -6.7 -7.3 -7.3
Standing height 2.9 28.6 50.4 -0.5 -0.8 -4.5 -5.6 -3.8 -4.7 4.6 -2.4 -6.4 -5.2 -7.1 -6.3 -5.6 -5.6 -6.0 -5.5 -4.9 -6.8 -6.1 5.4 -6.2 -6.4 -6.4
Length of working week for main job 1.7 1.8 5.2 1.6 1.4 -0.6 1.2 0.6 0.6 0.1 -2.3 1.1 1.2 1.2 1.8 1.4 1.2 1.5 0.7 1.4 1.4 1.8 -1.8 1.7 1.2 1.4
Exposure to tobacco smoke at home 0.2 0.3 1.1 0.8 -0.1 1.1 0.8 -0.1 0.6 -0.7 0.4 -0.1 0.7 0.7 0.4 0.4 0.0 0.1 0.8 0.4 0.8 0.1 -0.2 0.2 0.5 0.5
Breastfed as a baby 0.2 0.2 0.8 -0.4 0.2 0.2 0.3 0.7 0.2 -0.6 0.6 -0.3 0.2 0.8 0.5 0.3 0.4 0.3 0.0 0.2 0.9 0.4 -0.7 0.4 0.8 0.5
Tense / ‘highly strung’ 0.7 1.1 1.8 -1.0 -1.2 0.3 -1.1 -1.0 -1.1 -1.3 0.7 -0.6 -1.0 -1.1 -1.2 -1.1 -1.1 -1.0 -1.1 -1.1 -1.3 -1.1 0.5 -1.0 -1.3 -1.0
Seen doctor (GP) for nerves, anxiety, tension or depression 0.2 0.4 1.7 -0.6 1.1 0.2 0.3 0.3 1.0 0.7 1.3 0.2 0.2 0.6 0.6 0.3 0.4 0.3 0.6 0.3 0.9 0.5 -0.1 0.4 0.8 0.5
Hair/balding pattern: Pattern 4 0.3 0.8 4.2 -0.3 0.4 -0.9 -1.3 -0.2 -2.0 -0.8 -0.2 -0.0 -0.7 -1.5 -1.0 -0.7 -0.5 -0.5 -0.8 -0.5 -1.6 -0.6 -0.2 -0.5 -1.3 -0.9
Birth weight of first child 2.2 3.9 6.5 -1.2 -2.1 -0.7 -2.0 -1.6 -1.0 0.6 1.6 -1.9 -2.2 -2.2 -2.6 -2.3 -2.2 -2.4 -2.2 -2.2 -2.3 -2.4 2.0 -2.3 -2.0 -2.2
Peak expiratory flow (PEF) 2.7 6.2 19.2 0.8 -0.4 -1.9 -2.9 -1.1 -4.0 1.4 -1.8 -3.1 -1.9 -4.4 -3.0 -2.1 -2.0 -2.1 -2.2 -1.7 -3.8 -2.1 1.6 -2.2 -3.5 -2.8
Pulse wave reflection index 0.3 0.3 1.3 -0.6 -1.1 0.9 -0.6 0.4 -0.4 -0.4 0.6 0.2 -0.5 -0.4 -0.5 -0.5 -0.1 -0.4 -0.2 -0.5 -1.1 -0.5 0.2 -0.4 -0.7 -0.4
Ever highly irritable/argumentative for 2 days 0.3 0.3 2.4 1.6 -1.3 0.5 0.4 0.8 0.6 0.2 0.4 0.2 0.3 0.1 0.2 0.3 0.5 0.2 0.7 -0.0 0.5 0.3 -0.1 0.3 0.5 0.5
Loud music exposure frequency 1.3 1.5 3.4 0.9 1.5 1.6 1.2 0.2 1.8 1.3 0.4 1.5 0.9 1.0 1.1 1.1 1.2 1.5 0.2 1.0 1.4 1.4 -1.0 1.3 1.4 1.3
Qualifications: O levels/GCSEs or equivalent 0.2 0.4 2.5 0.2 -0.5 0.3 -0.1 0.9 -0.0 1.6 0.9 1.0 0.2 0.4 0.6 0.3 0.5 0.3 0.6 0.3 -0.3 0.5 -0.9 0.4 -0.0 0.4
Mouth/teeth dental problems: Bleeding gums 2.6 3.3 12.4 1.7 1.1 3.5 1.9 2.1 1.8 1.3 0.5 1.5 1.9 1.1 1.6 1.8 1.9 1.9 2.0 1.4 1.7 1.9 -1.9 1.8 2.1 1.6
Blood clot in the leg (DVT) 0.4 0.6 6.0 0.1 1.4 -1.3 0.1 0.2 -0.8 0.2 -2.4 -0.3 0.5 -0.5 0.4 0.5 0.3 0.3 0.3 0.8 -0.3 0.5 -0.1 0.5 -0.4 -0.2
Medication: Paracetamol 0.4 0.6 3.2 -0.7 0.1 1.4 0.5 0.1 1.5 -0.2 1.8 1.2 -0.0 1.1 0.4 0.1 0.3 0.3 0.2 0.0 1.0 0.3 0.0 0.3 1.0 0.3
Headache pain in last month 0.1 0.2 1.1 -0.8 -0.8 1.0 0.3 -0.4 1.0 0.1 0.6 0.2 -0.2 0.4 0.1 -0.1 -0.1 -0.1 -0.2 -0.1 0.3 -0.1 0.3 -0.1 0.1 -0.0
Medication for cholesterol, blood pressure or diabetes 1.1 1.8 4.5 2.1 0.2 1.4 1.4 0.7 1.7 1.7 0.2 0.7 1.3 1.4 1.8 1.4 1.2 1.3 1.4 1.1 1.5 1.5 -1.5 1.4 1.1 1.6
Glaucoma (self-reported) 0.6 0.7 2.8 -1.2 0.0 -1.7 -0.6 -0.6 -0.9 1.3 -1.2 -1.1 -0.3 -1.0 -0.9 -0.4 -0.4 -0.5 -0.5 -0.5 -0.2 -0.5 0.8 -0.5 -0.6 -0.8
Gout (self-reported) 0.4 0.5 1.6 -0.8 0.6 -1.2 -0.7 -0.1 -0.7 1.1 -0.0 -0.3 -0.6 -1.0 -1.3 -0.6 -0.3 -0.4 -1.0 -0.7 -0.3 -0.6 1.1 -0.7 -0.2 -0.7
Hypothyroidism/myxoedema (self-reported) 0.2 0.4 3.6 0.4 1.9 1.3 0.5 0.6 1.1 0.8 0.2 -0.1 0.2 0.2 0.3 0.2 0.5 0.4 0.3 -0.0 0.8 0.2 0.1 0.2 0.7 0.2
Medication: Amlodipine 0.3 0.5 4.1 -0.1 -0.1 0.7 -0.6 -0.4 -0.5 -0.9 2.0 0.2 -0.5 -0.5 -0.7 -0.6 -0.5 -0.5 -0.5 -0.9 -0.5 -0.6 0.3 -0.5 -0.5 -0.6
Medication: Ventolin 100micrograms inhaler 0.4 0.5 1.9 -0.9 -1.2 -0.6 -0.1 -1.4 0.6 1.0 0.2 -0.2 -0.3 -0.4 -0.5 -0.5 -0.8 -0.8 -1.1 -0.6 -0.6 -0.7 0.8 -0.6 -0.4 -0.5
Birth weight 3.2 7.0 10.3 -1.6 -2.2 -1.8 -2.9 -2.1 -1.1 2.3 2.2 -2.1 -3.2 -2.3 -2.9 -3.2 -2.9 -3.2 -3.1 -3.2 -2.5 -3.2 2.7 -3.2 -2.7 -2.9
Chronic bronchitis/emphysema (mother) 1.1 1.3 4.6 -0.3 -1.1 -1.5 -0.4 -1.9 1.1 1.2 0.3 -1.0 -1.1 0.1 -0.8 -1.2 -1.6 -1.5 -1.3 -1.1 -0.1 -1.1 2.1 -1.2 -0.4 -0.9
High blood pressure (siblings) 1.6 2.3 5.7 -1.8 -0.7 0.2 -1.7 -0.6 -2.4 -1.7 -0.8 -1.0 -1.2 -2.0 -1.8 -1.4 -1.2 -1.3 -0.8 -1.1 -2.2 -1.7 1.1 -1.6 -2.0 -1.8
Forced vital capacity (FVC), Best measure 1.4 5.1 10.3 1.5 -0.2 -2.6 -2.4 -1.1 -2.4 2.6 -2.0 -2.8 -1.9 -3.1 -2.3 -2.0 -2.1 -2.2 -2.2 -1.5 -3.2 -2.1 1.7 -2.2 -3.1 -2.6
Body fat percentage 1.2 4.8 14.8 -0.6 -0.7 -3.9 -1.8 -1.6 -1.2 1.4 -2.5 -3.3 -2.1 -2.1 -2.2 -2.3 -2.3 -2.5 -1.2 -2.5 -1.1 -2.5 3.2 -2.4 -1.3 -2.2
Leg fat percentage (right) 1.2 4.5 9.7 -1.6 -1.0 -2.7 -1.9 -1.4 -1.5 0.1 -1.6 -3.0 -2.1 -2.2 -2.4 -2.3 -2.2 -2.4 -1.4 -2.5 -1.5 -2.5 3.1 -2.4 -1.6 -2.4
Arm fat-free mass (right) 5.1 26.4 48.4 -3.6 -1.8 -4.6 -5.8 -3.2 -6.2 1.8 -2.8 -5.7 -5.0 -7.0 -6.1 -5.3 -5.0 -5.5 -5.0 -5.1 -6.6 -5.5 4.7 -5.5 -6.1 -6.1
Exposure to tobacco smoke outside home 0.2 0.3 0.8 -0.9 0.2 -0.5 -0.1 -0.2 -0.5 0.6 0.1 -0.9 0.1 -0.8 -0.7 -0.3 -0.5 -0.6 -0.2 -0.3 -0.2 -0.8 0.6 -0.6 -0.2 -0.3
Comparative body size at age 10 0.3 0.9 9.9 -1.3 -0.6 -0.8 -0.9 0.2 -1.0 0.8 3.1 -0.5 -0.4 -1.3 -0.4 -0.3 -0.1 -0.3 -0.4 -0.5 -1.0 -0.1 -0.7 -0.1 -1.0 -0.6
Number of full brothers 0.2 0.3 1.7 -0.4 0.7 -1.1 -0.4 -1.3 0.0 -0.1 0.3 0.0 -0.5 0.4 -0.1 -0.4 -0.5 -0.3 -1.3 -0.5 0.3 -0.2 0.6 -0.3 0.2 -0.0
Worry too long after embarrassment 0.6 1.0 3.6 -0.7 -0.1 0.7 0.7 1.9 -0.4 -1.0 -1.1 0.8 1.0 0.3 0.7 1.0 1.4 1.3 1.4 1.1 -0.1 1.3 -1.7 1.2 0.3 0.9
Seen a psychiatrist for nerves, anxiety, tension or depression 1.8 2.4 5.3 0.7 0.4 1.2 1.8 1.9 1.9 0.2 0.5 1.2 1.7 2.3 2.0 1.6 1.6 1.5 1.8 1.6 1.9 1.5 -1.4 1.5 1.8 1.4
Wheeze or whistling in the chest in last year 1.2 2.2 7.4 -1.1 -2.7 -1.7 -0.8 -1.6 0.8 -0.2 0.2 -1.3 -1.7 -0.1 -1.2 -1.8 -1.7 -1.9 -1.5 -2.0 -0.4 -1.6 2.6 -1.6 -0.6 -1.3
Number of children fathered 2.2 2.5 5.5 -2.3 -0.6 -1.1 -1.7 -2.2 -0.6 0.7 1.5 -0.8 -1.8 -0.9 -1.8 -1.8 -1.7 -1.8 -2.2 -1.6 -1.1 -1.6 2.0 -1.8 -1.4 -1.5
Reason for reducing amount of alcohol drunk: Health precaution 0.3 0.3 4.5 -0.1 -0.7 0.0 0.7 -0.4 1.1 -0.3 2.1 0.3 0.3 0.2 -0.4 0.0 -0.2 -0.1 0.3 -0.1 0.1 -0.3 0.1 -0.4 -0.0 -0.1
Age at first live birth 0.4 0.7 2.3 0.3 1.5 0.7 0.4 0.2 -0.4 -1.5 -1.4 0.7 0.6 0.3 0.6 0.8 1.0 1.0 0.3 1.1 0.1 1.1 -1.3 1.0 -0.0 0.5
Pulse wave peak to peak time 1.5 1.7 3.1 -0.3 -1.3 -1.2 -1.4 -1.0 -1.5 0.6 0.2 -1.8 -1.2 -1.6 -1.6 -1.4 -1.5 -1.3 -1.5 -1.2 -1.2 -1.5 1.2 -1.6 -1.3 -1.4
Health satisfaction 0.5 0.6 5.5 0.2 -2.4 -0.2 0.3 -0.3 1.2 -1.4 0.5 -0.6 -0.3 0.8 0.0 -0.4 -0.3 -0.4 0.1 -0.6 0.8 -0.3 1.2 -0.4 0.6 0.1
Shortness of breath walking on level ground 1.4 1.7 5.7 -0.8 -2.0 -2.0 -0.9 -0.5 -0.3 0.2 -1.3 -1.1 -1.4 -0.3 -1.1 -1.6 -1.5 -1.8 -0.8 -1.7 -0.3 -1.6 2.4 -1.6 -0.3 -1.1
Qualifications: College or University degree 0.1 0.4 2.5 1.2 1.6 -0.1 0.3 0.4 0.1 1.1 -1.5 0.2 0.5 -0.6 -0.2 0.4 0.4 0.4 0.3 0.9 -0.6 0.3 -0.3 0.2 -0.3 -0.1
Eye problems/disorders: None of the above 1.9 2.2 4.6 1.2 0.8 2.1 1.6 1.3 1.6 0.2 0.6 1.7 1.4 1.8 1.6 1.4 1.4 1.5 1.4 1.5 1.4 1.6 -1.5 1.6 1.6 1.6
Mouth/teeth dental problems: Loose teeth 1.6 2.0 4.8 -1.1 -1.1 -0.7 -1.3 -1.4 -0.9 1.0 0.2 -2.2 -1.4 -1.2 -1.5 -1.5 -1.7 -1.9 -1.0 -1.4 -1.0 -1.8 1.8 -1.8 -1.1 -1.7
Emphysema/chronic bronchitis 0.7 0.8 2.7 0.7 0.5 0.4 0.8 0.1 1.2 -1.7 -1.6 -0.1 0.4 1.5 1.1 0.4 0.2 0.2 0.4 0.4 1.4 0.5 0.3 0.5 1.2 0.8
Medication for pain relief, constipation, heartburn 0.5 0.9 3.6 0.6 -0.4 -1.9 -1.1 -1.3 -1.2 0.8 -1.5 -1.1 -0.9 -0.6 -0.3 -0.7 -0.8 -0.7 -1.1 -1.0 -0.9 -0.5 0.5 -0.5 -1.2 -0.8
Neck or shoulder pain in last month 3.0 4.3 10.0 -3.2 -1.8 -2.0 -2.1 -2.1 -2.2 -1.0 -1.8 -1.8 -2.1 -1.9 -2.3 -2.2 -2.1 -1.9 -2.1 -1.9 -1.7 -2.0 2.8 -2.1 -1.9 -2.0
Medication: Blood pressure 3.5 6.2 11.7 -2.5 -0.5 -1.5 -2.9 -1.6 -3.0 -1.1 0.2 -1.8 -2.5 -3.4 -3.1 -2.7 -2.5 -2.6 -2.6 -2.3 -3.4 -2.9 2.1 -2.7 -3.0 -3.1
Angina (self-reported) 1.5 1.9 6.6 -2.6 -1.0 -0.5 -1.6 -1.5 -1.2 -1.8 0.2 -0.7 -1.7 -0.9 -1.7 -1.6 -1.2 -1.3 -1.6 -1.7 -0.7 -1.4 1.6 -1.3 -0.8 -1.3
Migraine (self-reported) 0.3 0.3 1.7 0.1 -0.3 -0.6 -0.1 -1.1 -0.3 -0.3 -1.3 -1.1 -0.2 -0.1 -0.5 -0.3 -0.6 -0.4 -0.1 -0.3 0.2 -0.5 1.0 -0.6 -0.2 -0.5
Medication: Ibuprofen 0.3 0.4 1.3 -0.2 0.2 0.8 -0.3 0.2 -0.2 0.8 -1.1 -0.6 -0.4 -1.0 -0.9 -0.4 -0.3 -0.4 -0.1 -0.5 -0.7 -0.7 0.8 -0.8 -0.3 -0.5
Medication: Allopurinol 0.4 0.6 5.1 -0.6 1.3 -0.8 -0.4 -0.3 0.1 2.3 -0.3 -0.7 -0.5 -0.8 -0.8 -0.5 -0.3 -0.4 -0.7 -0.5 -0.4 -0.4 0.8 -0.5 -0.4 -0.7
Medication: Omeprazole 0.6 0.7 5.0 -1.6 -0.4 0.9 -0.4 -0.4 0.4 -0.1 2.2 -0.3 -0.6 -0.1 -0.8 -0.8 -0.8 -0.8 -1.0 -0.4 0.2 -0.9 0.8 -0.9 -0.0 -0.5
Medication: Seretide 50 evohaler 1.1 1.3 4.5 0.9 -0.1 0.2 1.5 0.7 2.1 1.3 0.1 0.7 1.1 1.7 1.4 1.1 1.0 0.9 0.9 0.8 1.4 1.1 -1.1 1.1 1.4 1.2
Mean time to correctly identify matches 0.4 0.7 4.4 -0.2 0.2 0.9 0.9 0.2 2.0 0.5 2.1 0.7 0.2 1.4 0.7 0.3 0.4 0.2 0.4 0.3 0.8 0.5 -0.3 0.5 0.7 0.5
Heart disease (mother) 0.2 0.2 1.2 -0.7 1.1 -0.4 -0.5 -0.2 -0.5 -0.3 0.4 0.6 -0.4 -0.4 -0.5 -0.4 -0.3 -0.4 -0.4 -0.1 -0.7 -0.4 0.2 -0.2 -0.5 -0.5
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.7 0.9 2.6 -0.6 -0.5 -1.1 -0.9 0.4 -1.6 -0.8 0.4 -0.9 -0.5 -1.6 -1.3 -0.7 -0.6 -1.0 -0.2 -0.7 -1.2 -1.1 0.9 -1.1 -1.0 -1.0
Whole body fat mass 3.2 13.5 23.8 -2.0 -1.6 -4.9 -3.7 -2.7 -3.1 1.7 -2.6 -4.9 -3.7 -4.3 -4.2 -4.0 -3.8 -4.2 -3.0 -4.1 -3.3 -4.1 4.5 -4.0 -3.3 -4.1
Leg fat mass (right) 3.5 13.6 22.3 -2.6 -1.8 -4.5 -3.8 -2.6 -3.3 0.8 -2.3 -4.7 -3.8 -4.4 -4.3 -4.0 -3.8 -4.2 -3.1 -4.2 -3.5 -4.2 4.5 -4.1 -3.5 -4.2
Arm predicted mass (right) 5.1 26.3 46.9 -3.8 -1.9 -4.6 -5.8 -3.4 -6.2 1.4 -2.8 -5.7 -5.0 -6.8 -6.1 -5.3 -5.0 -5.5 -5.0 -5.1 -6.5 -5.5 4.7 -5.5 -6.0 -6.0
Pulse rate, automated reading 1.0 3.1 6.7 1.3 1.3 0.6 1.5 0.7 1.8 -0.2 -0.4 2.0 1.2 2.2 2.4 1.7 2.0 2.2 1.2 1.1 2.5 2.6 -1.8 2.5 2.1 1.9
Alcohol intake frequency. 1.0 2.4 7.5 -0.4 0.0 0.5 1.8 -0.0 2.1 -2.4 2.2 0.6 1.3 1.9 1.6 1.3 1.1 1.2 0.9 1.3 2.7 1.7 -0.6 1.7 2.3 1.6
Comparative height size at age 10 2.9 15.9 28.4 -1.5 -0.1 -4.1 -4.5 -3.4 -3.5 2.0 -0.2 -3.9 -4.3 -4.8 -4.6 -4.3 -4.1 -4.4 -4.5 -4.1 -5.3 -4.2 3.9 -4.3 -5.0 -4.9
Number of full sisters 0.2 0.2 1.4 0.6 -0.9 -1.2 0.3 -0.9 0.0 -0.3 -0.1 -0.5 0.2 -0.0 0.2 0.0 -0.7 -0.4 -0.2 0.2 -0.4 -0.3 0.2 -0.2 -0.3 -0.1
Suffer from ‘nerves’ 0.2 0.3 3.0 -0.5 -0.5 -0.3 -0.2 -0.1 -0.3 -0.7 1.7 1.1 0.0 -0.4 -0.3 0.0 0.1 0.1 -0.4 0.1 -0.6 0.4 -0.8 0.5 -0.3 -0.0
Overall health rating 0.5 1.0 3.7 -1.1 -0.2 0.5 1.6 0.4 1.9 -1.3 1.3 0.5 1.0 1.2 0.7 0.7 0.6 0.4 0.6 1.0 1.5 0.6 -0.0 0.5 1.5 0.9
Chest pain or discomfort 0.4 0.6 2.1 -0.1 -1.0 0.1 0.9 1.0 1.4 -1.0 0.2 0.5 0.5 1.2 0.5 0.3 0.3 -0.1 0.7 0.1 1.3 -0.1 0.9 0.0 1.4 0.8
Had major operations 0.3 0.4 5.8 -0.8 2.4 0.3 -0.1 -0.4 0.4 0.2 -1.0 0.1 -0.2 0.3 -0.1 -0.2 -0.0 0.0 -0.2 -0.1 -0.0 -0.1 0.4 -0.1 0.0 -0.3
Age at last live birth 0.6 0.9 2.7 1.6 1.3 0.8 0.9 0.6 0.8 -0.4 0.3 0.4 0.8 0.7 0.9 0.9 1.2 1.2 0.5 0.9 1.1 1.2 -1.1 1.2 0.7 0.9
Family relationship satisfaction 1.2 1.5 4.6 2.1 0.2 2.1 1.3 1.8 1.5 -0.3 1.2 0.7 1.0 0.4 0.4 0.9 1.4 1.3 1.6 0.8 1.4 1.0 -0.4 0.9 1.6 1.1
Leg pain on walking 3.2 4.0 9.2 -2.0 -2.3 -2.7 -2.1 -1.5 -1.4 -0.3 -1.3 -2.0 -2.4 -1.5 -2.1 -2.3 -2.1 -2.3 -1.7 -2.5 -1.2 -2.2 3.0 -2.1 -1.1 -1.7
Qualifications: NVQ or HND or HNC or equivalent 0.4 0.5 1.9 -1.2 0.0 -0.5 -0.9 -1.4 -1.2 -0.4 -0.1 -0.3 -0.5 -0.5 -0.3 -0.4 -0.7 -0.6 -1.0 -0.4 -1.1 -0.1 0.3 -0.1 -1.0 -0.7
Commuting to job workplace: Car/motor vehicle 0.8 0.9 2.4 -0.1 0.5 0.7 0.7 0.3 1.1 0.8 0.7 1.5 0.8 1.5 1.2 0.8 0.9 0.9 0.4 0.8 1.4 1.0 -0.5 1.1 1.1 1.2
Illness, injury, bereavement, stress in last 2 years 0.3 0.4 3.2 1.1 1.3 -0.7 0.1 -0.2 0.0 0.5 -1.8 0.1 0.0 0.4 0.6 0.3 0.1 0.2 0.2 0.0 0.1 0.2 -0.7 0.3 0.0 0.1
Medication: Aspirin 0.2 0.3 2.1 -0.8 -0.7 0.5 -0.1 0.8 -0.9 -0.9 1.5 0.5 0.1 -0.6 -0.5 -0.0 0.2 0.1 0.0 0.2 -0.5 -0.2 -0.4 -0.2 -0.3 -0.1
Supplements: Vitamin C 1.4 1.6 3.5 0.2 -1.4 -1.7 -1.2 -1.1 -0.9 -1.7 0.3 -1.9 -1.4 -1.0 -1.1 -1.4 -1.3 -1.4 -1.2 -1.9 -0.7 -1.2 1.3 -1.2 -1.0 -1.2
Knee pain experienced in last month 1.1 1.7 3.6 -1.1 -1.5 -1.3 -1.2 -1.6 -0.7 0.6 -0.4 -1.9 -1.4 -1.1 -1.4 -1.4 -1.5 -1.4 -1.0 -1.5 -0.9 -1.4 1.9 -1.5 -1.1 -1.4
Hypertension (Self-reported) 0.4 1.2 5.3 -1.1 0.4 0.9 -1.1 0.3 -1.5 -1.0 1.3 0.4 -0.5 -2.1 -1.2 -0.7 -0.5 -0.7 -0.6 -0.3 -2.3 -0.8 -0.4 -0.8 -1.6 -1.4
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.8 0.9 3.3 0.3 -0.7 0.3 1.2 0.6 1.5 0.2 1.2 0.9 0.9 1.4 0.9 0.8 0.8 0.8 0.7 0.7 1.8 0.8 -0.6 0.8 1.5 0.9
Illnesses of father: Heart disease 0.9 1.2 2.4 -1.4 -1.4 0.8 -1.3 -0.8 -1.4 -1.6 -0.1 -1.1 -1.1 -1.5 -1.3 -1.1 -0.8 -0.8 -1.3 -1.0 -1.0 -0.9 0.8 -1.0 -1.1 -1.2
Illnesses of siblings: Diabetes 0.8 0.9 2.9 -1.6 -0.8 -1.1 -0.6 -0.5 -0.4 -0.3 -0.6 -1.1 -0.8 -0.8 -1.1 -1.0 -0.9 -1.2 -0.7 -0.8 -0.9 -1.2 1.7 -1.2 -0.5 -1.0
Smoking status: Previous 2.3 3.5 5.7 -2.1 -1.1 0.3 -2.0 -1.5 -0.9 -0.7 1.6 -2.2 -2.2 -2.0 -2.4 -2.3 -1.9 -2.0 -1.5 -2.2 -1.6 -2.4 2.3 -2.3 -1.6 -1.9
Forced expiratory volume in 1-second (FEV1), predicted 4.7 9.8 14.2 -0.9 -2.0 -3.4 -3.4 -1.8 -2.7 3.1 -0.8 -3.1 -3.3 -3.8 -3.7 -3.4 -3.1 -3.3 -2.9 -3.5 -3.7 -3.5 3.5 -3.7 -3.5 -3.5
Whole body fat-free mass 6.3 36.0 60.1 -4.3 -3.2 -5.0 -6.7 -4.5 -6.4 2.3 -1.9 -6.8 -6.1 -7.8 -7.0 -6.4 -6.1 -6.6 -6.0 -6.2 -7.4 -6.5 5.8 -6.6 -7.0 -7.1
Leg fat-free mass (right) 5.8 30.7 49.8 -3.6 -3.1 -5.3 -6.2 -4.3 -6.0 2.0 -2.1 -6.5 -5.7 -7.1 -6.3 -5.9 -5.7 -6.1 -5.4 -5.8 -6.5 -6.0 5.3 -6.0 -6.2 -6.4
Arm fat percentage (left) 1.6 6.5 14.9 -1.4 -1.7 -3.9 -2.4 -1.9 -1.9 1.2 -1.8 -3.6 -2.6 -2.6 -2.7 -2.8 -2.7 -3.0 -1.6 -3.1 -1.6 -2.9 3.5 -2.8 -1.8 -2.7
Average weekly red wine intake 0.1 0.1 0.4 -0.2 0.5 -0.6 -0.1 0.2 -0.6 -0.4 0.4 -0.0 0.0 -0.2 -0.5 -0.1 -0.1 -0.3 -0.1 -0.1 -0.2 -0.3 0.3 -0.2 -0.2 -0.1
Handedness (chirality/laterality): Left-handed 0.1 0.2 1.2 -0.5 0.3 0.4 -0.1 1.1 0.2 0.0 0.8 0.1 -0.1 -0.8 -0.2 0.0 0.6 0.2 0.0 -0.2 -0.5 0.3 -0.1 0.2 -0.2 -0.4
Mood swings 1.8 3.2 5.8 -1.7 -1.5 -1.4 -1.5 -1.9 -0.2 0.4 1.2 -2.4 -2.1 -1.2 -1.7 -2.2 -2.2 -2.3 -1.8 -2.1 -1.5 -2.1 2.2 -2.1 -1.6 -1.9
Loneliness, isolation 0.1 0.2 0.9 0.3 0.0 -0.0 0.1 1.0 -0.6 0.3 0.0 0.2 0.5 -0.3 0.2 0.5 0.5 0.5 0.3 0.6 -0.2 0.5 -0.6 0.4 0.0 0.3
Long-standing illness, disability or infirmity 1.2 1.8 9.1 -3.0 -2.0 -0.9 -0.7 -0.6 0.0 -2.2 0.1 -0.4 -1.3 0.0 -1.0 -1.4 -1.1 -1.5 -1.5 -1.4 -0.3 -1.5 2.0 -1.4 -0.5 -1.3
Ever had bowel cancer screening 0.3 0.4 2.3 -0.5 0.3 1.5 0.4 0.0 0.9 -0.9 1.2 0.3 0.1 0.7 0.1 0.1 0.2 0.1 1.0 0.1 0.9 -0.1 0.2 0.1 0.8 0.3
Diabetes diagnosed by doctor 4.3 7.0 10.1 -3.0 -1.8 -2.6 -3.0 -2.6 -2.9 0.0 -2.9 -2.2 -2.9 -2.3 -2.9 -2.9 -2.6 -2.5 -3.2 -2.9 -2.4 -2.7 3.0 -2.7 -2.3 -2.8
Ever had stillbirth, spontaneous miscarriage or termination 0.4 0.4 1.6 0.5 0.8 1.0 0.5 0.2 1.3 1.1 1.1 0.3 0.3 0.4 0.3 0.3 0.4 0.4 0.4 0.3 0.6 0.4 -0.3 0.4 0.4 0.5
Friendships satisfaction 3.6 4.5 9.0 2.6 1.3 2.7 2.6 1.7 3.0 -1.2 1.6 1.2 2.1 1.9 2.0 2.0 2.0 2.0 2.4 1.7 2.9 2.0 -1.5 1.9 2.8 2.3
Qualifications: nursing, teaching 0.6 1.0 3.5 0.1 -0.1 -0.7 -0.8 -0.2 -1.3 0.1 -0.6 -1.3 -0.5 -1.8 -1.3 -0.8 -0.8 -1.1 -0.2 -0.2 -1.9 -1.1 0.8 -1.1 -1.6 -1.3
Commuting to job workplace: Walk 1.9 2.1 3.9 -0.9 -0.9 -1.9 -1.6 -0.9 -1.7 0.8 0.3 -1.7 -1.3 -1.6 -1.6 -1.4 -1.4 -1.5 -1.2 -1.4 -1.8 -1.6 0.8 -1.6 -2.0 -1.7
Eye problems/disorders: Cataract 0.1 0.1 0.4 0.4 -0.1 -0.5 -0.2 0.1 -0.2 0.4 -0.2 -0.4 -0.1 -0.6 -0.1 -0.1 -0.1 -0.2 -0.3 -0.3 -0.4 -0.2 -0.3 -0.2 -0.5 -0.3
Mouth/teeth dental problems: Mouth ulcers 0.3 0.5 3.2 0.2 -1.8 1.3 -0.1 0.1 0.9 0.9 1.8 0.4 -0.5 0.4 0.1 -0.2 0.1 0.1 0.2 -0.9 0.3 0.2 -0.0 0.2 0.4 0.1
Medication for cholesterol 0.5 0.7 3.3 -0.2 1.4 -1.4 0.7 -0.8 0.1 -0.6 -1.8 0.0 0.7 0.8 0.8 0.8 0.5 0.6 0.1 0.9 1.0 0.8 -0.5 0.9 0.5 0.8
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.2 0.2 2.2 -0.0 -0.6 0.7 0.4 0.6 -0.2 -1.5 0.5 -0.1 0.4 0.0 -0.0 0.3 0.4 0.2 0.5 0.3 0.3 -0.1 -0.2 0.0 0.3 0.2
Back pain experienced in last month 1.4 2.0 5.6 -2.0 -1.3 -1.4 -0.9 -2.0 -0.0 -1.7 -1.3 -1.3 -1.6 -0.4 -1.0 -1.4 -1.6 -1.5 -1.5 -1.8 -0.4 -1.1 2.4 -1.2 -0.6 -1.5
Mineral and other dietary supplements 0.9 1.3 7.8 0.5 1.9 0.7 0.4 1.1 -0.6 1.4 -2.8 0.8 1.0 0.1 0.7 1.0 1.1 1.3 1.1 1.3 0.3 1.0 -1.1 1.1 0.3 0.8
Breast cancer (self-reported) 0.9 1.1 2.0 -0.9 1.4 0.6 0.8 0.9 0.5 0.4 -1.1 0.9 0.9 1.3 1.2 1.1 1.3 1.4 0.7 1.2 0.9 1.2 -1.4 1.3 0.8 0.9
Asthma (self-reported) 0.3 0.5 3.7 0.3 -1.4 1.0 0.5 -1.0 1.9 0.6 1.0 -0.6 -0.2 0.1 -0.0 -0.4 -0.7 -0.6 -0.5 -0.2 0.4 -0.5 0.7 -0.6 0.3 -0.1
Osteoporosis (self-reported) 0.9 1.2 6.2 -0.1 -0.2 1.4 0.6 0.8 0.5 -1.8 2.5 1.4 0.6 1.2 0.9 0.8 0.9 0.9 0.6 0.6 1.2 0.7 -1.0 1.0 1.0 1.2
Osteoarthritis (self-reported) 0.9 1.2 3.5 -1.7 -0.7 -1.9 -0.8 -1.3 -0.6 -1.2 -0.3 -1.1 -0.9 -0.3 -0.6 -0.9 -1.1 -1.4 -1.3 -1.0 -0.8 -1.2 1.2 -1.0 -0.8 -1.1
Medication: Aspirin 0.3 0.4 1.4 -1.2 -0.9 0.4 -0.4 0.7 -1.2 -1.2 0.8 0.4 -0.1 -0.9 -0.7 -0.2 -0.0 -0.2 -0.2 -0.1 -1.0 -0.4 -0.2 -0.4 -0.6 -0.4
Medication: Gliclazide 0.8 0.9 2.4 -1.4 -0.6 -0.1 -0.9 -1.3 -0.5 -0.9 -0.3 -0.5 -1.2 -0.5 -0.9 -1.1 -1.0 -0.9 -1.4 -1.6 -0.7 -1.0 0.9 -1.0 -0.7 -0.9
Illnesses of father: None of the above (group 1) 0.5 0.6 4.1 1.3 -0.6 -1.3 0.5 -0.2 1.1 2.0 1.1 0.1 0.3 0.3 0.7 0.4 0.2 0.3 0.4 0.1 0.5 0.6 -0.7 0.5 0.4 0.7
Smoking status: Current 2.1 3.4 7.6 -1.6 -1.1 -1.8 -1.9 -1.2 -0.8 2.1 -0.3 -1.4 -2.1 -1.5 -2.1 -2.2 -2.0 -2.0 -2.1 -1.9 -1.4 -2.1 2.8 -2.3 -1.6 -2.0
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.4 0.8 2.9 1.3 -0.7 -1.7 -0.9 -0.4 -0.9 0.3 -0.2 -1.2 -0.8 -0.7 -0.7 -0.9 -1.0 -1.0 -0.5 -0.8 -0.7 -0.8 1.2 -0.8 -0.8 -0.9
Whole body water mass 6.3 35.8 59.1 -4.3 -3.2 -5.0 -6.7 -4.5 -6.4 2.2 -2.0 -6.7 -6.1 -7.7 -7.0 -6.4 -6.1 -6.5 -6.0 -6.2 -7.4 -6.5 5.7 -6.6 -7.0 -7.0
Leg predicted mass (right) 5.7 30.5 49.8 -3.6 -3.1 -5.3 -6.2 -4.3 -6.1 2.0 -2.2 -6.4 -5.7 -7.1 -6.3 -5.9 -5.7 -6.1 -5.4 -5.8 -6.5 -5.9 5.3 -6.0 -6.2 -6.4
Arm fat mass (left) 3.6 14.9 25.2 -2.6 -2.0 -4.8 -4.0 -2.9 -3.5 1.6 -2.3 -5.0 -3.9 -4.5 -4.3 -4.2 -4.0 -4.4 -3.1 -4.4 -3.6 -4.3 4.7 -4.3 -3.6 -4.4
Number of self-reported non-cancer illnesses 1.4 2.4 11.6 -3.4 -0.7 -0.1 -0.9 -2.0 -0.6 -1.6 -0.1 -1.1 -1.2 -1.2 -1.6 -1.5 -1.8 -1.9 -1.2 -1.1 -1.4 -2.0 2.1 -1.8 -1.2 -1.6
Average weekly champagne plus white wine intake 0.4 0.6 1.6 0.7 0.1 0.5 0.6 1.0 0.1 0.8 -0.5 0.6 0.9 -0.2 0.7 0.8 0.9 0.9 1.0 1.0 0.1 0.9 -1.3 0.8 0.5 0.5
Miserableness 0.2 0.4 4.6 -0.1 0.5 -0.7 -0.3 -0.0 0.4 2.1 0.1 -1.0 -0.4 -0.4 -0.2 -0.4 -0.4 -0.5 -0.5 -0.4 -0.2 -0.2 0.1 -0.3 -0.3 -0.3
Guilty feelings 0.3 0.5 2.2 -0.3 -1.0 -1.2 -0.7 0.2 0.1 1.5 0.1 -0.2 -0.9 -0.1 -0.4 -0.8 -0.7 -0.8 -0.5 -0.8 -0.6 -0.8 0.5 -0.8 -0.6 -0.8
Wears glasses or contact lenses 1.5 1.7 2.9 0.9 0.2 1.5 1.6 1.7 1.7 -0.1 0.4 0.7 1.4 0.8 1.2 1.3 1.5 1.3 1.6 1.7 1.2 1.4 -1.6 1.4 1.4 1.3
Ever taken oral contraceptive pill 1.7 1.9 5.2 2.1 -0.5 0.8 1.3 1.4 2.3 1.8 1.3 1.1 0.9 1.6 1.7 1.1 1.2 1.2 1.3 0.6 1.2 1.4 -1.1 1.3 1.4 1.6
Hearing aid user 1.2 1.4 3.7 0.1 1.3 1.3 1.6 0.8 1.5 -0.1 0.1 1.4 1.6 1.3 1.1 1.4 1.2 1.2 0.5 1.9 0.9 1.1 -1.1 1.2 0.9 1.2
Mother’s age at death 0.8 1.0 6.0 -0.9 -0.4 -0.2 -1.1 -0.1 -2.1 -2.4 -1.4 -0.6 -0.6 -0.9 -0.6 -0.6 -0.5 -0.7 -0.8 -0.3 -1.4 -0.6 -0.1 -0.6 -1.3 -0.8
Financial situation satisfaction 2.5 3.1 6.9 2.5 -0.3 2.3 1.9 1.6 2.6 0.6 2.5 0.9 1.6 1.9 1.7 1.4 1.5 1.4 1.9 0.9 2.4 1.4 -1.1 1.3 2.1 2.0
Tinnitus: Yes, now most or all of the time 0.5 0.6 1.9 0.5 0.6 0.8 0.8 0.9 1.0 1.4 0.3 0.9 0.8 0.2 0.4 0.8 1.0 1.1 0.7 0.9 0.5 0.9 -0.7 0.8 0.5 0.5
Commuting to job workplace: Public transport 1.3 1.5 3.8 0.2 0.6 1.9 1.5 1.7 1.1 1.4 1.2 0.8 1.7 0.1 0.5 1.4 1.2 1.2 1.8 1.5 0.6 1.1 -1.4 1.0 0.9 0.9
Eye problems/disorders: Glaucoma 0.3 0.4 1.1 -1.0 -0.6 -1.1 -0.4 -0.8 -0.6 0.2 -0.8 -0.8 -0.2 -0.9 -0.6 -0.3 -0.4 -0.3 -0.3 -0.5 -0.3 -0.4 0.6 -0.4 -0.6 -0.6
Medication: Blood pressure 0.2 0.4 2.6 -0.0 0.2 1.6 -0.0 1.6 -0.1 0.5 1.0 0.7 0.3 -0.7 -0.1 0.2 0.4 0.2 0.3 0.5 -1.1 0.1 -0.8 0.1 -0.4 -0.3
Pain type(s) experienced in last month: Hip pain 2.4 3.0 4.7 -2.0 -1.0 -1.8 -1.7 -2.1 -1.1 -0.6 0.9 -1.4 -1.8 -1.8 -1.8 -1.9 -2.0 -2.0 -2.2 -1.7 -1.6 -1.9 2.1 -1.9 -1.8 -2.0
Supplements: Fish oil (including cod liver oil) 0.9 1.1 3.2 -1.4 -1.8 -0.7 -0.7 -1.3 0.2 -0.8 1.7 -0.9 -1.0 -0.5 -1.0 -1.1 -1.2 -1.2 -1.2 -1.2 -0.5 -0.9 1.1 -1.1 -0.4 -1.0
High cholesterol (Self-reported) 0.2 0.3 1.6 -0.9 -0.9 -0.6 -0.5 -0.4 -0.2 -0.6 -0.1 -0.3 -0.6 0.1 -0.7 -0.7 -0.5 -0.5 0.0 -0.6 0.2 -0.7 1.2 -0.7 0.2 -0.4
Medication: Bendroflumethiazide 0.3 0.5 1.4 -0.8 0.8 0.1 -0.4 -0.2 -0.0 1.0 0.8 -0.7 -0.4 -1.0 -0.8 -0.7 -0.7 -0.8 -0.1 -0.2 -1.2 -0.8 0.4 -0.8 -0.9 -0.9
Medication: Paracetamol 0.2 0.3 2.1 -1.4 0.2 0.6 -0.0 -0.5 0.7 -1.0 1.1 0.3 -0.4 0.6 -0.1 -0.3 -0.2 -0.3 -0.3 -0.4 0.4 -0.3 0.4 -0.2 0.3 -0.4
Medication: Lisinopril 2.0 2.5 9.3 -0.6 -2.1 1.1 -1.4 -0.6 -1.7 -0.3 1.0 -1.9 -1.0 -3.0 -2.0 -1.3 -1.2 -1.4 -1.1 -1.1 -2.6 -1.6 0.9 -1.6 -2.1 -1.8
Medication: Atorvastatin 0.6 0.7 1.7 -0.5 0.3 -1.3 -0.8 -0.4 -0.4 -0.8 -0.9 -0.9 -1.1 -0.8 -0.8 -1.0 -0.8 -0.9 -0.9 -1.0 -1.0 -0.8 0.8 -0.8 -0.8 -0.9
Illnesses of father: High blood pressure 0.4 0.5 3.4 -0.5 0.6 -0.0 -0.5 0.4 -1.8 -1.8 -0.6 -0.1 0.0 -1.0 -0.5 -0.1 -0.1 -0.3 -0.3 -0.2 -1.0 -0.3 -0.2 -0.3 -0.9 -0.8
Alcohol drinker status: Never 0.2 0.2 2.3 0.4 -1.5 -1.4 0.3 0.1 -0.5 -0.7 0.0 0.0 0.5 0.0 0.2 0.3 -0.0 -0.1 -0.0 0.2 -0.0 0.1 -0.3 0.1 0.0 0.1
Ever smoked 4.9 8.7 13.5 -3.1 -1.5 -0.7 -3.3 -2.6 -2.6 0.6 0.2 -3.1 -3.2 -3.2 -3.4 -3.4 -3.2 -3.2 -3.2 -2.9 -3.3 -3.7 3.1 -3.6 -3.3 -3.4
Basal metabolic rate 6.5 35.7 58.5 -4.2 -3.0 -5.4 -6.6 -4.5 -6.3 2.5 -2.3 -6.8 -6.1 -7.7 -7.0 -6.4 -6.1 -6.6 -5.9 -6.2 -7.2 -6.5 5.9 -6.6 -6.8 -7.0
Leg fat percentage (left) 0.9 3.3 7.3 -1.7 -0.4 -2.6 -1.6 -1.1 -1.4 -0.1 -2.1 -2.6 -1.7 -1.9 -2.1 -1.9 -1.8 -2.1 -1.1 -2.0 -1.2 -2.1 2.7 -2.0 -1.3 -2.0
Arm fat-free mass (left) 5.8 29.6 50.6 -4.3 -2.4 -4.5 -6.1 -3.8 -6.1 1.5 -2.4 -6.1 -5.4 -7.1 -6.4 -5.7 -5.4 -5.9 -5.4 -5.4 -6.8 -5.9 5.2 -6.0 -6.4 -6.5
Number of operations (self-reported) 0.2 0.4 2.8 -0.4 1.4 1.7 0.6 0.3 0.6 -0.8 -0.2 -0.3 0.5 0.2 0.2 0.4 0.3 0.4 0.3 0.8 0.4 0.1 0.0 0.1 0.3 0.3
Average weekly beer plus cider intake 0.7 1.0 8.5 -0.1 -0.2 0.7 0.5 0.9 0.9 2.9 -0.3 1.4 0.6 0.6 0.6 0.7 1.0 1.0 0.7 0.7 0.2 1.0 -1.0 0.9 0.5 1.0
Irritability 0.1 0.2 2.2 -0.0 0.4 0.7 0.3 1.5 0.4 -0.3 -0.3 0.7 -0.0 0.4 0.3 0.1 0.6 0.4 0.1 -0.0 0.2 0.4 -0.5 0.4 0.4 0.3
Risk taking 0.7 1.0 3.1 0.2 -1.7 0.1 -0.5 -1.4 0.9 1.7 0.9 -0.9 -1.0 0.2 -0.4 -1.1 -1.4 -1.1 -1.1 -1.3 -0.4 -1.1 1.1 -1.1 -0.5 -0.4
Ever had prostate specific antigen (PSA) test 0.2 0.2 2.5 -0.9 0.5 -0.5 -0.1 -0.5 0.1 -1.6 0.1 0.1 -0.3 0.3 -0.4 -0.4 -0.4 -0.5 -0.1 0.1 -0.4 -0.2 0.2 -0.3 -0.4 -0.4
Fractured/broken bones in last 5 years 0.5 0.6 2.0 0.8 1.4 0.7 0.8 1.0 0.9 -0.5 -0.1 0.8 0.6 1.0 0.4 0.6 0.9 0.9 0.6 0.6 1.1 0.6 -0.3 0.6 0.6 0.8
Age started oral contraceptive pill 4.3 5.4 10.2 2.6 2.8 1.6 2.6 2.2 1.4 -2.2 0.9 2.0 2.8 1.7 2.5 2.7 2.4 2.3 2.2 3.1 1.7 2.4 -3.2 2.5 1.8 2.4
Diastolic blood pressure, automated reading 0.3 0.9 5.6 1.9 0.6 0.7 0.5 0.5 1.1 2.1 2.4 0.6 0.5 -0.2 0.4 0.5 0.4 0.4 0.5 0.3 -0.4 0.5 -1.1 0.5 -0.2 0.0
Ever depressed for a whole week 0.3 0.3 1.2 1.0 -0.6 0.4 0.3 1.1 0.4 0.2 0.8 0.3 0.3 0.2 0.6 0.4 0.5 0.4 0.9 -0.1 0.4 0.5 -0.2 0.5 0.6 0.7
Unable to work because of sickness or disability 0.2 0.2 1.9 -1.4 -0.0 0.1 -0.1 -0.1 -0.5 -0.9 1.1 0.3 0.2 0.2 -0.1 -0.0 -0.1 -0.1 -0.1 0.4 0.2 -0.3 0.3 -0.2 0.0 -0.1
Commuting to job workplace: Cycle 0.1 0.2 1.0 0.3 -0.8 0.2 -0.0 0.4 -0.6 -0.3 -0.8 -0.1 0.2 -0.5 -0.4 0.1 0.0 -0.0 0.3 0.2 -1.0 -0.0 -0.3 -0.1 -0.6 -0.2
Myopia 0.6 0.9 2.4 0.2 0.4 0.6 1.1 0.0 1.5 1.4 1.2 0.1 1.1 1.0 1.1 1.0 0.6 0.6 1.0 1.2 0.8 0.9 -1.2 0.9 0.7 0.6
Vascular/heart problems diagnosed by doctor 0.6 1.6 5.0 1.8 -0.2 -1.0 1.4 -0.1 1.8 1.5 -1.3 0.1 0.9 2.0 1.4 1.1 0.8 1.0 1.1 0.6 2.2 1.2 -0.0 1.1 1.7 1.6
Cholesterol lowering medication 0.2 0.2 0.9 -0.1 -1.0 0.5 -0.4 0.6 -0.1 -0.6 0.6 -0.1 -0.6 -0.2 -0.5 -0.6 -0.2 -0.4 0.2 -0.7 -0.0 -0.6 0.8 -0.6 0.0 -0.4
Medication: Omeprazole (e.g. Zanprol) 0.4 0.5 2.4 -1.5 0.1 1.0 0.4 0.1 1.2 -0.3 1.5 0.0 0.0 1.0 0.2 -0.1 -0.2 -0.3 0.2 0.5 1.0 -0.2 0.2 -0.2 0.7 0.2
Pain experienced in last month 1.0 1.6 5.2 2.3 1.4 1.0 0.9 1.4 0.2 0.3 0.8 1.3 1.4 0.6 1.1 1.4 1.3 1.3 1.3 1.5 0.6 1.2 -2.2 1.3 0.9 1.4
Supplements: Calcium 0.4 0.4 3.3 -0.3 0.4 -1.8 -0.6 -0.1 -0.1 -0.8 0.9 -0.0 -0.9 0.5 -0.0 -0.7 -0.4 -0.8 -0.5 -0.9 0.3 -0.6 0.6 -0.4 -0.3 -0.5
Basal cell carcinoma (self-reported) 0.9 1.1 7.6 -0.5 -0.3 -0.3 0.4 1.4 -1.4 -2.8 -1.7 0.1 0.8 -0.7 0.3 0.8 0.9 0.6 0.8 1.0 -1.1 0.8 -1.6 0.8 -0.6 0.1
Heart attack/myocardial infarction (self-reported) 0.5 0.7 1.6 -1.2 0.4 -0.2 -0.9 -1.0 -0.6 -0.5 0.9 -0.7 -0.9 -1.0 -1.3 -0.9 -0.7 -0.7 -0.9 -0.7 -0.5 -0.7 1.2 -0.8 -0.4 -0.7
Deep venous thrombosis (DVT) (self-reported) 0.5 0.6 4.1 -0.5 0.8 -1.5 -0.5 -0.3 -1.3 -0.1 -2.0 -0.8 -0.1 -1.0 -0.3 -0.1 -0.3 -0.3 -0.3 0.3 -0.8 -0.1 0.5 -0.1 -0.9 -0.7
Heart disease (siblings) 0.6 0.7 1.7 -1.1 -0.5 0.6 -0.8 -0.4 -0.7 -0.6 1.2 -0.3 -0.7 -1.0 -1.3 -0.9 -0.7 -0.7 -0.6 -0.7 -0.7 -1.1 1.0 -1.0 -0.7 -0.9
Alcohol drinker status: Previous 1.4 1.5 11.6 -0.9 -0.9 2.3 0.9 -0.5 2.4 -0.7 3.4 0.1 0.3 1.2 0.9 0.4 0.3 0.6 0.5 0.3 1.6 0.8 -0.1 0.8 1.4 1.0
Pack years of smoking 0.4 0.5 1.7 -1.1 -0.5 -0.5 -0.9 -0.4 -0.4 -0.5 -0.3 0.1 -1.1 0.4 -0.5 -0.9 -0.8 -0.8 -0.8 -0.9 -0.1 -0.8 1.3 -0.9 -0.3 -0.8
Impedance of whole body 2.5 12.6 27.7 5.3 3.2 2.3 4.2 2.5 4.6 1.2 -0.2 3.1 3.7 4.3 4.0 3.7 3.1 3.5 3.5 3.8 4.3 3.4 -2.6 3.4 4.0 4.0
Leg fat mass (left) 3.4 13.1 21.0 -2.8 -1.6 -4.5 -3.7 -2.6 -3.3 0.7 -2.6 -4.6 -3.7 -4.2 -4.2 -3.9 -3.7 -4.1 -3.0 -4.0 -3.4 -4.1 4.3 -4.0 -3.4 -4.1
Arm predicted mass (left) 5.8 29.4 51.4 -4.2 -2.2 -4.5 -6.0 -3.8 -6.1 1.6 -2.5 -6.2 -5.4 -7.2 -6.4 -5.7 -5.4 -5.9 -5.3 -5.4 -6.8 -5.8 5.1 -5.9 -6.4 -6.5