Best TWAS P=6.14e-08 · Best GWAS P=8.61e-09 conditioned to 0.00945
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Muscle Skeletal | DLG4 | 0.12 | 0.05 | lasso | 4 | 0.05 | 2.3e-05 | -4.8 | 5.4 | 6.1e-08 | 0.74 | 0.09 | 0.90 | TRUE |
| 2 | GTEx | Skin Sun Exposed Lower leg | CTDNEP1 | 0.10 | 0.06 | lasso | 6 | 0.06 | 9.5e-06 | -4.5 | 5.3 | 1.4e-07 | 0.61 | 0.14 | 0.81 | FALSE |
| 3 | The Cancer Genome Atlas | Testicular Germ Cell Tumors | C17orf81 | 0.13 | 0.09 | blup | 43 | 0.08 | 1.1e-03 | -4.4 | -5.2 | 2.2e-07 | -0.62 | 0.02 | 0.78 | FALSE |