Best TWAS P=1.63e-07 · Best GWAS P=6.7e-08 conditioned to 0.0556
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Coronary | RP11-810M2.2 | 0.30 | 0.02 | lasso | 4 | 0.02 | 0.085 | 5.1 | 5.2 | 1.6e-07 | 0.89 | 0.02 | 0.76 | TRUE |
| 2 | GTEx | Brain Putamen basal ganglia | AC012146.7 | 0.30 | 0.03 | enet | 23 | 0.03 | 0.076 | 3.7 | -5.2 | 2.2e-07 | 0.03 | 0.02 | 0.12 | TRUE |
| 3 | GTEx | Muscle Skeletal | ZZEF1 | 0.11 | 0.01 | lasso | 3 | 0.01 | 0.019 | 5.1 | 5.2 | 2.3e-07 | 0.97 | 0.01 | 0.96 | FALSE |