Best TWAS P=1.53e-09 · Best GWAS P=1.18e-09 conditioned to 0.0399
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Cells Transformed fibroblasts | TFPI | 0.07 | 0.04 | lasso | 4 | 0.03 | 1.6e-03 | -5.6 | -6.0 | 1.5e-09 | 0.81 | 0.10 | 0.84 | TRUE |
| 2 | NTR | Blood | CALCRL | 0.02 | 0.03 | lasso | 7 | 0.02 | 3.6e-08 | -5.6 | 5.6 | 2.2e-08 | -0.80 | 0.13 | 0.87 | FALSE |
| 3 | The Cancer Genome Atlas | Brain Lower Grade Glioma | CALCRL | 0.03 | 0.04 | blup | 62 | 0.04 | 1.4e-05 | -5.3 | 5.9 | 2.9e-09 | -0.84 | 0.12 | 0.87 | FALSE |