Hub : Genes

TFPI

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Adipose Visceral Omentum	0.0990	0.0480	0.00700	0.019	NA	0.038	NA	0.025	3.3e-02	NA	4.5e-03	NA	1.8e-02
2	GTEx	Cells Transformed fibroblasts	0.0720	0.0320	0.00032	0.043	NA	0.026	NA	0.033	3.6e-04	NA	4.3e-03	NA	1.6e-03
3	GTEx	Esophagus Muscularis	0.2880	0.0680	0.00004	0.092	NA	0.097	NA	0.067	3.0e-06	NA	1.7e-06	NA	6.9e-05
4	GTEx	Heart Atrial Appendage	0.3240	0.1140	0.00660	0.093	NA	0.037	NA	0.062	5.7e-05	NA	8.9e-03	NA	9.4e-04
5	GTEx	Muscle Skeletal	0.1139	0.0423	0.00120	0.079	NA	0.075	NA	0.081	3.8e-08	NA	8.0e-08	NA	2.6e-08
6	GTEx	Skin Sun Exposed Lower leg	0.0800	0.0330	0.00085	0.040	NA	0.026	NA	0.028	2.9e-04	NA	3.1e-03	NA	2.2e-03
7	ROSMAP	Brain Pre-frontal Cortex	0.0556	0.0240	0.00069	0.005	0.014	0.003	0.015	0.008	6.4e-02	0.0049	1.1e-01	0.0048	3.0e-02
8	TCGA	Colon Adenocarcinoma	0.0780	0.0530	0.00510	0.042	0.032	0.023	NA	0.025	1.7e-03	0.0060	1.7e-02	NA	1.3e-02

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8
Bipolar Disorder (2018)	0.2	0.4	1.2	0.4	0.4	-0.2	-0.7	-0.9	-0.0	1.1	-0.2
Bipolar Disorder or Schizophrenia	0.6	1.4	3.6	-1.0	0.6	-0.9	-1.4	-1.9	-1.0	1.6	0.5
Depressed Affect (Nagel 2018)	0.8	1.8	6.5	-2.5	-0.7	-1.0	-0.1	-0.0	-1.1	-2.0	-1.0
Depression (Nagel 2018)	0.2	0.3	1.0	-0.7	-0.0	-0.6	0.0	-0.2	-0.8	-0.5	1.0
Intelligence (Savage-Jansen 2018)	0.2	0.8	1.9	0.0	-1.0	1.1	0.9	0.6	0.2	-0.9	-1.4
Neuroticism (Nagel 2018)	1.1	2.6	8.4	-2.9	-0.7	-2.1	-0.8	-0.6	-1.7	-1.7	-0.7
Schizophrenia (2018)	0.7	1.4	2.9	-1.3	0.4	-1.1	-1.4	-1.7	-1.3	1.1	0.8
Schizophrenia vs Biploar Disorder	0.4	0.5	1.8	-0.1	-0.9	-0.0	-0.4	-0.5	-1.0	-1.3	-0.1
Worry (Nagel 2018)	0.8	1.6	4.6	-2.1	-0.7	-1.8	-0.2	-0.1	-1.6	-1.2	-0.6
Alzheimer’s Disease (in mother)	0.4	0.5	1.9	0.3	-1.4	0.4	0.5	0.3	1.0	-0.4	-0.4
Alzheimer’s Disease (in father)	2.1	2.2	5.3	1.7	0.1	1.2	2.3	1.9	1.8	1.0	0.6
Alzheimer’s Disease (including proxy)	0.9	1.3	4.0	0.2	-2.0	0.7	1.5	1.2	1.2	0.1	-0.9
Crohns Disease (2017)	0.1	0.3	1.0	1.0	-0.5	0.7	0.6	0.3	0.1	-0.4	0.3
Irritable Bowel Disease (IBD)	0.3	0.7	2.4	1.6	0.0	1.0	0.6	0.3	0.1	-0.8	1.1
Ulcerative Colitis (UC)	0.2	0.5	1.3	1.0	0.2	0.7	0.0	-0.2	-0.0	-0.9	1.1
Major Depression (MDD)	0.4	0.5	1.5	-0.1	0.7	-0.8	1.1	1.2	-0.1	-0.5	0.2
Reaction Time	0.2	0.4	0.9	-0.0	-0.0	-1.0	0.3	0.9	0.4	0.6	-0.9
Verbal and Numeric Reasoning (VNR)	0.5	1.3	2.9	0.9	0.2	0.9	1.5	1.4	1.1	-1.7	-0.5
Breast Cancer	1.8	4.4	8.3	-2.9	-1.7	-1.9	-2.5	-2.1	-2.9	-0.5	-1.4
Ovarian Cancer	0.9	1.2	4.9	-0.2	-1.6	0.8	0.7	0.8	0.3	-0.9	-2.2
Prostate Cancer	0.6	0.9	3.0	0.3	1.6	0.1	-0.2	-0.4	0.1	1.2	1.7
Age at First Birth	0.4	0.6	0.9	0.9	0.9	0.1	0.9	0.8	-0.9	-0.4	0.5
Bipolar Disorder (2011)	0.8	0.7	2.0	0.9	0.8	1.0	0.6	0.4	0.7	1.4	-0.6
Body Mass Index (BMI) (2010)	0.9	1.2	2.4	-1.6	-1.3	-1.1	-1.2	-1.4	0.3	-0.7	-0.5
Coronary Artery Disease (CAD)	0.4	0.5	1.7	-0.1	0.1	0.8	-0.6	-1.1	-0.2	1.3	-0.5
Crohns Disease (2012)	0.1	0.2	0.7	0.7	-0.0	0.8	0.1	-0.4	0.2	0.1	0.7
Mean Putamen Volume	0.6	0.6	1.7	-1.2	0.2	-0.7	-1.3	-0.7	-0.8	0.0	0.6
Fasting Glucose	0.9	1.1	4.9	1.6	0.4	0.8	-0.0	0.4	2.2	-0.7	0.3
HbA1C	0.4	0.4	1.3	0.2	-0.9	1.1	-0.1	-0.5	-0.5	-0.0	-0.8
HDL Cholesterol	0.8	1.3	2.4	1.5	1.0	1.0	0.8	0.3	1.2	1.3	1.4
LDL Cholesterol	0.6	1.0	6.1	-0.6	0.6	-0.8	-0.1	-0.2	-2.5	0.4	0.5
Lupus	0.8	1.2	3.1	-0.4	-1.6	0.0	-0.4	-0.0	1.7	-1.8	-0.9
Neuroticism (2016)	2.6	3.7	10.6	-2.9	-0.3	-1.6	-0.8	-0.5	-3.3	-2.7	-0.6
Primary Biliary Cirrhosis	0.8	1.1	4.8	1.1	2.2	0.6	0.9	1.0	0.3	0.5	0.3
Rheumatoid Arthritis	0.3	0.4	1.6	0.6	0.3	1.3	0.4	0.4	0.9	-0.5	0.1
Schizophrenia (2014)	1.3	3.0	9.5	-1.6	-0.6	-1.6	-2.5	-3.1	-1.6	0.2	0.2
Triglycerides	0.7	1.1	4.4	-1.1	-1.3	-0.9	-0.5	0.1	-2.1	0.1	-0.3
Type 2 Diabetes (T2D) (2012)	0.9	1.0	4.0	-0.4	-0.7	0.2	-0.2	0.0	-0.5	-2.0	-1.8
Ulcerative Colitis	0.2	0.3	1.0	1.0	-0.1	1.0	0.3	0.0	0.1	-0.7	0.4
Blood Eosinophil Count	0.9	6.8	28.6	-1.3	-5.3	-0.4	-0.5	-0.1	0.6	-3.3	-3.5
Blood Platelet Count	0.1	1.2	2.6	-0.6	-0.7	-1.6	-1.2	-1.0	1.3	-1.5	0.5
Blood Red Count	0.5	4.6	13.1	-1.7	-3.6	-0.2	-1.2	-1.5	-3.3	-1.6	-2.0
Blood White Count	1.9	14.3	45.3	-4.5	-6.7	-2.2	-2.0	-2.1	-0.9	-2.5	-5.4
Heel T-Score	0.9	7.5	20.7	3.2	4.5	2.0	0.3	-0.4	1.1	3.9	3.0
BMI	1.2	6.8	21.3	-2.0	-4.6	-1.7	-2.8	-3.0	1.7	-2.0	-1.7
Height	0.5	9.2	19.8	3.6	4.5	2.7	3.5	3.0	-2.6	0.7	2.1
Waist Hip Ratio (WHR)	5.3	24.0	69.4	-2.7	-8.3	2.6	1.1	1.6	2.8	-6.1	-7.7
Systolic Blood Pressure	0.5	2.5	5.7	-0.3	-1.5	0.4	2.1	2.4	-1.7	-0.9	-1.8
Smoking Status	0.5	1.2	2.4	-0.2	1.4	1.0	1.6	0.9	0.9	0.8	1.5
Allergy or Eczema	1.7	4.4	15.0	2.2	3.4	-0.6	-0.4	-0.5	0.1	1.8	3.9
Cardiovascular Disease	1.9	6.1	16.8	-2.1	-3.3	0.1	0.8	1.1	-1.2	-3.7	-4.1
Hypothyroidism (self reported)	0.6	1.3	4.6	-2.1	-1.3	-0.8	-0.2	-0.7	-1.6	-0.1	-0.3
Respiratory disease	0.3	0.7	4.0	0.3	-0.9	0.2	-0.1	0.1	-2.0	-0.9	0.1
Type 2 Diabetes (T2D) (2018)	0.8	1.4	3.2	1.2	-1.2	1.4	1.8	1.6	0.7	-0.4	-0.2
Lung FEV1/FVC ratio	1.7	8.6	31.6	-3.5	-3.7	-0.6	-1.8	-1.3	-1.2	-2.3	-5.6
Lung FVC	1.0	5.3	15.4	1.7	3.9	0.6	1.2	0.7	1.1	3.3	3.1
Neuroticism	0.4	1.0	3.6	-1.6	-0.2	-0.5	0.6	0.3	-1.9	-1.0	0.3
Chronotype (morning person)	1.0	2.4	5.8	2.4	1.4	1.2	0.9	0.7	2.1	1.2	1.6
Hair Pigment	0.0	0.9	4.3	-0.4	-0.2	0.7	-0.3	-0.7	-1.3	0.2	-2.1
Tanning	0.1	0.8	1.8	1.1	-0.1	0.8	0.8	0.6	1.3	1.3	0.5
Hand grip strength (left)	1.0	2.7	11.3	1.1	3.4	1.1	0.7	0.1	0.3	1.1	2.4
Number of treatments/medications taken	0.3	0.6	2.0	-0.5	-1.0	0.0	0.6	0.4	-0.8	-0.4	-1.4
Average weekly spirits intake	0.5	0.6	2.9	0.2	-0.2	-0.5	-0.1	0.0	1.7	-0.2	-1.1
Sensitivity / hurt feelings	0.2	0.4	0.9	-0.6	0.1	-0.3	0.9	0.7	0.2	0.8	0.9
Frequency of depressed mood in last 2 weeks	0.2	0.3	1.3	-0.7	-0.8	0.1	0.3	0.1	-1.1	-0.4	0.4
Hearing difficulty/problems: Yes	0.7	1.1	4.0	-2.0	0.4	-1.1	-0.9	-1.0	-1.1	0.7	0.6
Relative age of first facial hair	0.4	0.7	4.1	-0.5	-1.0	0.5	0.2	0.2	-0.4	-0.2	-2.0
Other serious medical condition/disability diagnosed by doctor	0.5	0.6	2.7	-0.5	1.2	-1.6	0.1	0.6	0.3	-0.3	0.2
Ever used hormone-replacement therapy (HRT)	0.6	0.7	2.1	0.6	0.4	1.3	0.9	0.4	1.5	0.4	0.5
Ever had hysterectomy (womb removed)	2.0	2.2	5.7	2.3	1.5	0.0	0.1	-0.1	1.2	2.4	1.8
Systolic blood pressure, automated reading	0.1	0.4	1.9	-0.2	-0.7	-0.3	0.2	0.4	-1.4	0.2	-0.7
Eye problems/disorders: Diabetes related eye disease	0.5	0.6	1.7	-0.5	-0.8	-0.8	0.2	-0.0	-1.3	0.4	1.1
Angina	0.9	1.2	2.8	-1.7	-1.2	-0.8	0.1	0.5	-0.6	-1.1	-1.6
Medication for hormone replacement therapy	0.9	1.0	4.2	0.1	0.8	-0.2	1.2	1.1	2.1	-0.6	-0.4
Vitamin and mineral supplements	1.1	1.5	3.6	0.9	0.2	0.2	1.6	1.6	1.9	1.4	-0.1
Supplements: Zinc	3.1	3.4	6.2	2.0	-0.3	2.5	2.2	2.4	1.4	-1.6	-1.4
Medication: Co-codamol	0.2	0.2	0.7	0.3	0.8	0.7	0.5	0.3	-0.1	0.1	-0.2
Medication: Metformin	0.2	0.3	1.0	-0.5	-0.7	0.2	-0.3	-0.5	-1.0	0.1	-0.3
Diabetes (father)	0.5	0.6	1.7	0.3	0.7	1.1	0.5	0.3	0.5	-1.3	-1.0
Diabetes (mother)	0.5	0.6	2.2	-0.4	-0.7	0.5	0.2	0.6	0.7	-1.5	-1.0
Severe depression (siblings)	1.1	1.2	3.9	0.4	-0.2	0.8	2.0	1.8	0.0	-0.4	-1.1
Pack years adult smoking proportion	0.2	0.3	0.8	0.4	-0.5	-0.3	0.5	0.9	0.3	-0.2	0.6
Impedance of leg (right)	0.5	2.4	6.1	0.1	0.2	1.5	1.5	1.9	-1.6	-2.5	-1.5
Leg fat-free mass (left)	0.1	0.7	1.6	-0.8	-0.6	-1.1	-1.0	-1.3	0.3	0.6	-0.1
Trunk fat percentage	0.7	3.0	7.6	-1.4	-2.8	-1.0	-1.6	-1.7	1.2	-1.4	-2.0
Hand grip strength (right)	0.9	2.5	5.6	1.6	2.4	1.8	1.7	1.2	-0.0	1.1	1.7
Townsend deprivation index at recruitment	0.5	0.7	2.7	-0.6	-1.4	-0.3	-0.0	0.1	-0.7	0.1	-1.6
Current tobacco smoking	1.0	1.6	6.4	0.4	1.3	-0.1	0.6	0.2	1.3	1.7	2.5
Average weekly fortified wine intake	0.2	0.2	0.3	-0.5	0.1	-0.5	-0.6	-0.5	0.1	-0.4	0.5
Maternal smoking around birth	0.3	0.5	2.0	-0.8	-0.5	-1.4	0.2	0.3	-0.3	0.0	0.8
Fed-up feelings	0.9	1.6	3.2	-0.8	-1.3	1.1	1.7	1.8	-0.7	-1.1	-1.1
Frequency of unenthusiasm / disinterest in last 2 weeks	0.9	1.2	3.1	-1.2	0.2	-0.6	-0.7	-1.2	-1.8	0.5	1.4
Relative age voice broke	0.2	0.4	1.2	1.1	0.4	0.8	0.5	0.7	-0.1	0.4	-0.3
Taking other prescription medications	0.3	0.5	1.1	-0.6	-1.1	-0.9	-0.4	-0.8	-0.4	0.2	-0.9
Age when periods started (menarche)	0.7	1.7	6.5	-0.1	2.0	-0.1	0.1	0.0	-2.5	1.7	0.7
Bilateral oophorectomy (both ovaries removed)	2.9	3.4	9.8	1.6	2.4	-0.3	0.0	-0.1	1.9	2.4	3.1
Heel bone mineral density (BMD) T-score, automated (left)	1.4	3.2	11.4	2.2	3.4	1.6	0.8	0.1	1.9	0.9	1.3
Tinnitus: Yes, but not now, but have in the past	0.4	0.5	1.3	0.6	0.4	0.1	0.4	0.3	1.0	1.1	-0.9
Qualifications: CSEs or equivalent	0.6	0.8	1.6	-1.2	-1.2	-0.2	-0.1	0.4	0.3	1.0	-1.3
Serious illness, injury or assault to yourself	0.6	0.7	1.9	-1.2	1.1	-1.0	-0.1	-0.1	-1.4	-0.2	-0.5
High blood pressure	1.4	3.9	11.5	-1.8	-2.8	-0.6	0.6	1.2	0.3	-2.4	-3.4
Hayfever, allergic rhinitis or eczema	1.0	2.2	7.3	1.7	2.4	-0.6	0.5	0.2	1.0	0.5	2.7
Multivitamins +/- minerals	0.8	1.0	2.7	-0.0	0.6	0.2	-0.9	-1.4	-1.4	0.0	1.7
Stomach or abdominal pain in last month	0.3	0.4	1.5	-0.2	0.1	0.5	0.7	0.2	-0.1	-1.2	-0.9
Supplements: Glucosamine	0.8	1.0	3.3	-0.8	-0.1	0.3	1.1	0.8	-1.2	-1.8	-0.7
Diverticular disease/diverticulitis (self-reported)	0.4	0.5	1.4	0.5	0.7	0.7	0.4	0.8	-1.2	0.5	0.3
Medication: Atenolol	1.8	2.3	4.4	-1.5	-1.6	-2.1	-1.7	-1.5	1.5	-1.2	-0.6
Medication: Levothyroxine sodium	0.9	1.5	3.8	-1.9	-0.9	-1.1	-0.8	-1.3	-1.9	-0.4	0.0
Sitting height	1.6	11.5	31.6	4.1	5.6	2.3	3.5	2.9	-1.0	2.3	3.4
Chronic bronchitis/emphysema (father)	0.7	0.8	3.3	0.8	0.4	0.3	-0.4	-0.5	1.0	0.8	1.8
High blood pressure (mother)	0.7	1.0	3.0	-0.6	0.9	-0.2	0.1	0.0	-1.7	-1.3	-1.6
Body mass index (BMI)	2.0	8.4	20.7	-3.0	-4.5	-2.5	-3.2	-3.2	1.4	-1.8	-2.3
Impedance of leg (left)	0.6	2.7	6.1	0.3	0.3	1.7	1.7	2.0	-1.9	-2.5	-1.3
Leg predicted mass (left)	0.1	0.6	1.5	-0.7	-0.7	-1.1	-1.0	-1.2	0.4	0.6	0.0
Trunk fat mass	0.7	2.9	8.5	-1.4	-2.9	-0.9	-1.3	-1.4	1.0	-1.5	-2.2
Waist circumference	3.4	12.6	36.5	-3.5	-6.0	-1.5	-2.9	-2.7	1.1	-3.5	-4.5
Number of incorrect matches in round	0.3	0.5	1.7	-1.3	-0.1	-1.0	-0.3	-0.4	0.6	0.0	-0.6
Past tobacco smoking	0.3	0.6	1.3	1.2	-0.0	-0.3	-1.0	-1.1	-0.4	0.7	-0.6
Alcohol usually taken with meals	2.9	4.7	8.8	2.8	0.1	3.0	2.6	2.5	2.8	-0.2	0.7
Nervous feelings	0.7	1.2	2.7	-0.6	-0.5	1.2	1.6	1.6	-0.9	-1.0	-0.8
Frequency of tenseness / restlessness in last 2 weeks	0.6	0.9	4.4	0.1	-0.4	1.2	0.3	0.2	-2.1	-0.3	-1.2
Hearing difficulty/problems with background noise	0.2	0.3	1.9	-1.4	-0.2	-0.4	0.2	0.5	-0.2	-0.4	-0.4
Hair/balding pattern: Pattern 2	2.7	3.4	9.2	-2.0	-0.1	-1.2	-2.7	-3.0	-2.0	-0.1	0.8
Had menopause	1.2	1.5	4.2	-0.6	0.3	-0.4	-1.5	-1.6	-0.9	1.2	2.0
Had other major operations	0.5	0.7	2.2	-1.2	-0.8	-1.5	-0.6	-0.7	-0.4	0.4	0.0
Forced vital capacity (FVC)	1.6	6.0	15.2	2.5	3.9	1.8	2.6	2.3	0.3	2.3	2.5
Heel bone mineral density (BMD) T-score, automated (right)	0.9	2.0	8.8	1.7	3.0	1.3	0.4	-0.3	1.2	0.5	1.1
Ever unenthusiastic/disinterested for a whole week	0.8	1.0	3.9	-1.1	-0.8	0.1	0.2	0.1	-1.5	-0.1	-2.0
Qualifications: None of the above	1.8	3.8	13.2	-2.4	0.2	-3.6	-2.1	-1.6	-1.4	-0.7	1.5
Financial difficulties in last 2 years	0.7	0.9	4.9	-0.3	0.3	-0.4	0.5	0.5	-2.2	1.0	-0.5
Mouth/teeth dental problems	0.3	0.4	1.3	1.1	-0.1	0.9	0.5	0.3	1.0	-0.0	-0.5
Heart attack	1.1	1.4	5.1	-1.5	-2.3	-0.8	-0.7	-0.6	-1.0	-0.9	-0.7
Allergy	0.6	1.3	5.7	-0.7	-1.1	1.3	0.3	0.7	0.9	-0.0	-2.4
Pain all over the body in last month	1.5	1.6	3.9	-1.7	0.8	-2.0	-1.3	-1.2	-0.6	1.1	0.7
Diabetes (self-reported)	0.2	0.2	1.2	0.3	-0.4	0.2	0.2	0.0	-1.1	0.5	-0.0
Hayfever/allergic rhinitis (self-reported)	1.3	1.7	4.8	2.2	1.0	1.1	0.8	0.4	1.0	1.3	1.7
Medication: Ramipril	1.8	2.3	5.0	-1.4	-1.9	0.5	1.6	1.9	-1.2	-0.7	-2.2
Medication: Simvastatin	1.6	2.4	9.2	-0.6	-2.1	0.4	0.5	0.5	-2.0	-0.5	-3.0
Fluid intelligence score	1.0	2.0	5.9	-0.3	-0.8	1.0	1.8	1.8	0.6	-2.4	-1.3
Illnesses of siblings	0.7	0.9	4.4	0.5	-0.6	0.7	1.2	0.6	0.5	2.1	0.3
Neuroticism score	0.4	0.9	1.8	-1.1	-0.5	0.3	1.4	1.0	-1.3	-1.1	-0.3
Weight	0.6	3.2	8.1	-1.9	-2.8	-1.4	-1.7	-1.8	0.3	-1.5	-1.8
Impedance of arm (right)	1.5	6.9	19.7	2.9	4.4	2.1	2.6	2.0	-0.0	2.4	2.3
Arm fat percentage (right)	0.9	3.6	9.2	-1.6	-3.0	-1.4	-1.9	-2.1	1.7	-1.0	-1.8
Trunk fat-free mass	0.1	0.7	2.0	-0.9	-1.4	-0.7	0.0	0.2	-0.4	-1.3	-1.0
Hip circumference	0.7	2.9	6.8	-1.6	-1.4	-1.9	-2.6	-2.6	-0.5	-0.8	-0.8
Time employed in main current job	0.4	0.4	1.4	0.2	1.0	-1.2	-0.1	-0.1	-0.6	0.3	0.6
Alcohol intake versus 10 years previously	2.4	3.7	9.3	-3.0	-2.1	-2.4	-2.1	-2.2	-0.5	-0.2	-0.4
Father’s age at death	0.8	1.1	3.7	1.4	1.9	-0.3	-0.3	0.1	0.2	-0.0	1.7
Worrier / anxious feelings	0.6	1.1	3.5	-0.2	0.1	-0.0	1.8	1.9	-1.2	-0.1	-0.4
Frequency of tiredness / lethargy in last 2 weeks	0.2	0.4	1.7	-0.3	0.3	0.7	0.7	0.5	-1.3	-0.0	-0.2
Falls in the last year	0.4	0.5	1.6	0.1	-0.2	-0.7	0.9	0.9	-0.2	1.3	0.3
Hair/balding pattern: Pattern 3	0.7	1.1	3.0	0.5	0.7	0.1	1.3	1.6	0.3	-0.8	-1.7
Number of live births	0.5	0.7	2.1	-0.4	-1.4	0.2	-0.6	-1.1	-0.9	0.6	0.1
Forced expiratory volume in 1-second (FEV1)	0.9	3.1	9.2	1.8	3.0	1.8	1.6	1.4	0.3	1.9	1.1
Pulse rate	0.9	1.6	7.3	0.7	2.7	-0.7	-0.4	-0.2	0.5	2.0	0.0
Happiness	1.5	1.8	6.6	-0.8	-0.3	-0.1	0.5	0.7	-2.6	-2.5	-0.3
Noisy workplace	1.4	1.8	8.9	-0.5	3.0	-1.0	-0.7	-0.7	-0.3	1.1	1.3
Qualifications: A levels/AS levels or equivalent	0.6	1.3	3.1	1.2	1.5	1.6	0.2	-0.3	-0.4	1.8	0.8
Serious illness, injury or assault of a close relative in last 2 years	0.3	0.3	1.4	-0.4	1.2	-0.7	0.4	0.3	-0.6	0.3	-0.2
Mouth/teeth dental problems: Dentures	0.6	1.0	4.0	-1.1	-0.0	-2.0	0.7	1.1	-0.6	-0.2	0.9
Asthma	0.3	0.6	2.4	0.8	-0.5	0.2	0.9	0.6	-1.6	-0.3	-0.4
Medication: Ibuprofen (e.g. Nurofen)	1.2	1.5	4.3	-1.6	0.3	-0.8	-1.9	-2.1	-0.7	0.2	0.6
Medication: Cholesterol lowering	1.5	2.4	4.8	-0.1	-2.0	0.6	2.0	2.2	-1.2	-0.6	-2.1
Depression (self-reported)	0.8	1.0	4.2	0.5	-0.8	0.6	0.7	0.7	-2.0	-0.0	-1.2
Medication: Lansoprazole	1.1	1.3	2.9	-1.7	-0.1	-1.7	-1.2	-1.2	-0.8	-0.5	0.7
Prospective memory result	0.6	0.7	1.6	-0.3	0.0	-0.6	-1.3	-1.1	0.3	1.2	0.9
Lung cancer (father)	0.8	0.9	2.2	-1.5	1.1	-1.4	-0.5	-0.1	-1.2	0.1	0.0
Illnesses of mother	1.2	1.5	4.9	1.3	0.6	0.5	0.6	0.8	2.2	1.5	1.3
Forced expiratory volume in 1-second (FEV1), Best measure	0.3	1.0	3.0	0.9	1.7	1.3	0.9	0.6	0.3	1.1	0.6
Pulse wave Arterial Stiffness index	1.8	2.1	5.6	-1.7	-2.4	-1.5	-0.7	-0.1	-0.5	-1.5	-1.6
Impedance of arm (left)	1.5	7.0	18.7	3.3	4.3	2.3	2.3	1.8	-0.1	2.5	2.5
Arm fat mass (right)	1.0	4.3	11.0	-2.0	-3.3	-1.7	-2.2	-2.2	1.2	-1.6	-1.9
Trunk predicted mass	0.1	0.7	2.0	-0.9	-1.4	-0.8	-0.0	0.1	-0.4	-1.2	-0.8
Standing height	0.5	5.1	10.4	2.0	3.2	2.1	2.9	2.7	-2.4	0.4	0.8
Length of working week for main job	0.8	0.9	2.0	0.7	1.2	0.6	1.0	1.0	0.0	1.4	1.0
Exposure to tobacco smoke at home	0.1	0.1	0.3	0.3	-0.4	-0.1	0.5	0.2	0.2	-0.4	-0.5
Breastfed as a baby	1.1	1.4	3.1	-0.1	-0.3	1.0	1.5	1.8	-1.4	-1.6	-0.4
Tense / ‘highly strung’	0.2	0.4	2.1	-0.6	-0.5	-0.0	-0.1	-0.3	-1.4	0.4	0.4
Seen doctor (GP) for nerves, anxiety, tension or depression	0.2	0.4	2.7	0.1	0.3	-0.3	-0.2	-0.2	-1.6	-0.1	-0.1
Hair/balding pattern: Pattern 4	0.1	0.4	0.9	0.0	0.4	-0.3	-0.9	-0.8	0.5	0.7	-0.4
Birth weight of first child	2.0	3.7	7.4	2.7	1.8	2.5	2.0	1.4	1.0	2.0	1.2
Peak expiratory flow (PEF)	0.2	0.5	1.8	0.7	-0.1	1.3	0.8	0.5	-0.0	-0.7	0.3
Pulse wave reflection index	1.1	1.4	5.5	-1.3	-2.3	-0.2	0.0	0.2	0.3	-1.6	-1.1
Ever highly irritable/argumentative for 2 days	0.6	0.7	2.7	-1.6	-1.0	-0.7	0.1	-0.1	-0.1	0.1	-1.2
Loud music exposure frequency	1.0	1.1	3.2	0.6	0.6	0.1	1.3	1.4	1.8	0.4	0.7
Qualifications: O levels/GCSEs or equivalent	1.0	1.5	4.8	1.9	1.0	2.2	1.0	0.6	1.0	-0.6	0.4
Mouth/teeth dental problems: Bleeding gums	0.2	0.3	1.0	-1.0	-0.6	-0.3	0.4	0.2	0.9	-0.3	-0.0
Blood clot in the leg (DVT)	1.1	1.4	6.0	-0.8	-2.4	-1.2	-1.0	-0.8	-0.4	-1.2	0.3
Medication: Paracetamol	0.6	1.0	3.3	-0.3	1.8	-1.8	-0.4	-0.1	-0.3	0.8	0.8
Headache pain in last month	0.6	1.0	2.8	-0.7	1.4	-0.1	-0.8	-1.0	-1.7	0.5	0.9
Medication for cholesterol, blood pressure or diabetes	1.8	2.9	7.0	-0.3	1.5	-1.2	-2.6	-2.7	0.6	1.1	2.1
Glaucoma (self-reported)	3.2	3.7	5.6	1.3	-1.3	2.4	1.9	2.2	1.9	-2.3	-1.8
Gout (self-reported)	0.7	0.9	3.0	-0.0	-0.1	-0.0	-0.7	-1.1	-1.7	-1.3	-0.9
Hypothyroidism/myxoedema (self-reported)	0.5	0.9	2.1	-1.2	-1.5	-0.2	0.4	0.2	-1.2	-0.5	-1.2
Medication: Amlodipine	0.6	0.9	4.6	-0.7	-0.8	-0.6	-0.0	0.2	0.7	-0.6	-2.2
Medication: Ventolin 100micrograms inhaler	0.4	0.5	2.4	-0.5	-1.5	-0.6	0.2	-0.0	-0.6	0.5	0.3
Birth weight	0.9	1.9	5.7	1.7	1.6	0.6	0.1	-0.3	0.4	2.4	1.8
Chronic bronchitis/emphysema (mother)	1.3	1.6	8.0	-1.4	-0.4	-2.8	-0.8	-0.2	-0.9	-1.0	0.0
High blood pressure (siblings)	0.4	0.6	1.4	-0.2	0.9	-0.2	-1.1	-0.7	-0.3	-1.2	-0.8
Forced vital capacity (FVC), Best measure	1.3	4.6	12.5	2.2	3.5	1.9	2.1	1.5	0.2	2.1	2.1
Body fat percentage	1.1	4.4	13.1	-1.7	-3.6	-1.0	-1.7	-1.8	1.4	-1.9	-2.5
Leg fat percentage (right)	2.5	9.1	27.2	-3.1	-5.2	-1.8	-2.1	-1.9	1.1	-3.3	-3.6
Arm fat-free mass (right)	0.4	1.9	4.3	-1.6	-2.1	-1.3	-1.1	-1.0	-0.7	-1.7	-1.2
Exposure to tobacco smoke outside home	0.6	0.8	2.2	0.9	-0.2	0.7	1.5	1.0	0.9	0.6	0.8
Comparative body size at age 10	2.3	6.3	19.4	-2.4	-3.9	-0.3	-1.0	-0.8	-1.0	-2.6	-4.4
Number of full brothers	2.9	3.7	8.3	-2.3	-0.8	-2.2	-2.9	-2.8	-1.5	0.3	0.0
Worry too long after embarrassment	0.4	0.6	2.4	-0.5	-0.7	0.5	0.7	0.5	-1.6	-0.1	-0.9
Seen a psychiatrist for nerves, anxiety, tension or depression	0.8	1.0	3.4	-0.5	-0.7	0.3	-0.4	-0.2	-1.7	-0.8	-1.9
Wheeze or whistling in the chest in last year	0.8	1.3	4.7	-0.5	-2.2	-0.2	0.7	1.0	0.0	-0.8	-1.9
Number of children fathered	1.2	1.4	4.1	-1.3	-2.0	-0.9	-0.6	-0.4	0.0	-1.3	-1.5
Reason for reducing amount of alcohol drunk: Health precaution	0.8	1.0	1.8	-1.0	-0.7	-0.9	-1.4	-1.3	-0.5	-1.2	-0.6
Age at first live birth	0.3	0.5	1.1	0.7	0.0	0.7	0.9	0.9	-0.5	0.3	-1.0
Pulse wave peak to peak time	1.8	2.1	6.1	1.8	2.5	1.5	0.8	0.2	0.3	1.4	1.7
Health satisfaction	2.5	3.3	9.4	-1.7	-1.2	-1.1	-0.8	-0.3	-2.6	-3.1	-2.0
Shortness of breath walking on level ground	1.6	1.9	4.7	-1.4	-1.4	-2.2	-0.9	-0.3	-0.8	-2.0	-1.0
Qualifications: College or University degree	1.1	3.4	12.3	2.5	0.4	3.5	2.2	1.3	0.1	1.2	0.6
Eye problems/disorders: None of the above	0.5	0.6	1.1	-1.0	-0.2	-0.7	-1.0	-0.7	-1.1	0.5	-0.1
Mouth/teeth dental problems: Loose teeth	0.2	0.2	0.8	0.3	0.1	0.9	0.4	0.2	-0.4	0.4	-0.6
Emphysema/chronic bronchitis	2.2	2.5	5.1	-2.1	0.4	-2.2	-2.2	-2.0	-0.9	-1.1	-0.3
Medication for pain relief, constipation, heartburn	0.5	0.8	2.3	0.5	-0.8	1.0	0.6	0.9	0.5	-1.5	-1.0
Neck or shoulder pain in last month	0.3	0.5	1.4	-0.7	-0.3	0.7	0.4	0.0	0.2	1.2	-1.0
Medication: Blood pressure	1.3	2.3	7.8	-0.3	-1.6	0.4	1.5	1.7	-0.2	-1.4	-2.8
Angina (self-reported)	0.6	0.8	2.4	-1.5	-0.9	-0.9	0.3	0.6	-0.4	-0.9	-1.1
Migraine (self-reported)	0.9	1.1	4.3	1.3	2.1	-0.6	-0.5	-0.2	-0.6	1.3	-0.4
Medication: Ibuprofen	0.5	0.6	1.6	-0.9	0.9	-0.1	-0.8	-1.3	-0.1	1.0	0.5
Medication: Allopurinol	2.2	2.9	6.6	-1.5	-1.6	-0.0	-0.9	-1.2	-2.0	-2.3	-2.6
Medication: Omeprazole	2.3	2.7	4.2	-1.3	-2.1	-1.2	-1.8	-2.0	1.9	-1.4	-1.3
Medication: Seretide 50 evohaler	0.9	1.0	3.0	1.3	1.4	0.2	0.4	0.2	0.8	1.7	0.9
Mean time to correctly identify matches	0.2	0.3	1.7	0.4	0.1	-0.8	0.1	0.4	-0.0	1.3	-0.1
Heart disease (mother)	0.9	1.1	2.6	-0.1	1.2	1.0	-0.5	-0.9	-1.5	-0.4	-1.6
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.5	1.8	4.1	1.6	0.1	0.6	1.9	1.7	2.0	0.7	0.0
Whole body fat mass	1.0	4.3	13.4	-1.7	-3.7	-0.9	-1.6	-1.6	1.2	-1.9	-2.6
Leg fat mass (right)	1.7	6.6	20.9	-2.6	-4.6	-1.6	-2.0	-2.0	0.9	-2.4	-2.9
Arm predicted mass (right)	0.4	2.3	4.9	-1.6	-2.2	-1.1	-1.1	-1.0	-0.7	-2.2	-1.4
Pulse rate, automated reading	5.1	16.5	59.3	3.6	7.7	0.4	0.9	0.5	2.3	5.0	5.3
Alcohol intake frequency.	2.4	5.7	17.4	-2.3	-4.2	-2.0	-0.7	-0.3	1.4	-2.1	-3.5
Comparative height size at age 10	0.2	1.3	2.1	1.4	1.1	0.9	1.4	1.4	-0.7	0.7	1.4
Number of full sisters	0.9	1.1	3.0	-0.5	0.2	-1.6	-1.7	-1.4	-0.7	-0.8	0.2
Suffer from ‘nerves’	0.8	1.3	7.5	-0.4	0.8	0.3	0.5	0.5	-2.7	-1.0	-0.5
Overall health rating	0.7	1.6	3.1	-1.6	-0.1	-1.7	0.2	0.7	-1.8	-1.6	-0.8
Chest pain or discomfort	0.3	0.5	1.7	-0.8	-0.2	-1.3	-0.1	-0.1	0.2	-1.1	0.0
Had major operations	0.9	1.1	1.7	0.6	-1.3	1.2	1.3	0.9	1.0	-0.5	-1.2
Age at last live birth	0.7	1.0	3.6	0.7	-0.6	1.4	0.6	0.5	-0.9	0.0	-1.9
Family relationship satisfaction	1.0	1.2	2.4	-0.9	-0.9	-0.5	0.5	1.0	-1.4	-1.4	-1.6
Leg pain on walking	0.9	1.1	2.6	-1.1	0.0	-1.5	-1.1	-0.7	-0.1	-1.6	-0.8
Qualifications: NVQ or HND or HNC or equivalent	0.8	1.0	2.2	-1.1	-0.4	-1.5	-0.7	-0.7	-1.0	-0.8	-1.3
Commuting to job workplace: Car/motor vehicle	0.2	0.3	0.8	0.6	0.4	-0.3	0.5	0.3	0.4	0.5	0.9
Illness, injury, bereavement, stress in last 2 years	0.4	0.5	1.8	0.3	-0.3	1.3	0.9	0.7	0.6	-0.6	-0.5
Medication: Aspirin	0.5	0.7	2.7	-0.6	-0.9	-0.5	0.4	0.2	-1.6	1.1	-0.2
Supplements: Vitamin C	0.2	0.3	1.4	-0.1	-0.7	0.0	-0.2	-0.0	0.2	-1.2	0.5
Knee pain experienced in last month	1.7	2.6	8.0	-1.1	0.7	-1.2	-2.7	-2.8	-1.0	0.3	0.8
Hypertension (Self-reported)	1.7	4.8	15.1	-2.3	-3.2	-0.7	0.5	1.1	0.1	-2.4	-3.9
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.6	0.7	1.1	-1.0	-1.0	-0.7	-0.8	-0.9	0.7	-0.5	-1.0
Illnesses of father: Heart disease	2.1	2.9	5.3	-2.3	-1.8	-2.0	-2.3	-1.9	0.3	-1.1	-0.5
Illnesses of siblings: Diabetes	1.3	1.5	9.8	-0.8	-0.6	-0.2	0.0	0.0	1.0	-3.1	-0.8
Smoking status: Previous	0.9	1.4	4.9	-2.0	-0.7	-0.7	0.0	0.4	-0.5	-2.2	-0.7
Forced expiratory volume in 1-second (FEV1), predicted	0.5	1.0	2.9	0.6	1.7	1.2	1.0	0.9	-0.8	0.8	-0.2
Whole body fat-free mass	0.1	0.6	1.1	-0.9	-1.1	-1.0	-0.7	-0.7	-0.2	-0.6	-0.6
Leg fat-free mass (right)	0.1	0.5	1.2	-0.5	-0.2	-0.9	-0.8	-1.1	0.1	0.8	0.3
Arm fat percentage (left)	0.9	3.5	9.1	-1.3	-3.0	-1.2	-2.0	-2.1	2.0	-0.9	-1.7
Average weekly red wine intake	0.5	0.8	2.9	0.5	1.1	0.2	0.9	0.8	0.6	0.0	1.7
Handedness (chirality/laterality): Left-handed	0.4	0.5	1.3	0.5	-0.4	1.1	0.6	0.2	1.1	-0.5	-0.5
Mood swings	0.3	0.6	2.2	-1.1	-0.1	-0.3	0.5	0.2	-1.0	-1.5	-0.1
Loneliness, isolation	1.0	1.4	4.3	-2.1	-0.3	-0.8	-0.7	-0.5	-1.9	-0.6	-1.0
Long-standing illness, disability or infirmity	0.2	0.3	0.9	-0.1	0.9	-0.9	0.5	0.5	-0.2	0.6	-0.2
Ever had bowel cancer screening	2.6	3.0	10.1	-1.4	-3.2	-0.4	-1.7	-1.8	0.7	-1.0	-2.0
Diabetes diagnosed by doctor	0.1	0.2	0.4	0.5	-0.2	-0.2	-0.5	-0.5	-0.6	0.4	0.5
Ever had stillbirth, spontaneous miscarriage or termination	2.1	2.2	4.3	-1.3	1.0	-1.2	-1.6	-2.1	-1.7	0.8	1.8
Friendships satisfaction	0.4	0.5	1.4	-0.2	-0.5	0.2	1.2	1.1	-0.4	-0.1	-0.8
Qualifications: nursing, teaching	0.8	1.3	4.5	1.4	-0.1	2.1	0.4	0.1	1.1	-1.4	-0.6
Commuting to job workplace: Walk	0.8	0.8	4.2	-0.5	-0.3	0.2	-0.6	-0.6	-2.0	-1.2	0.1
Eye problems/disorders: Cataract	0.5	0.6	1.8	-0.3	1.4	-1.0	0.3	0.3	-1.1	0.3	0.1
Mouth/teeth dental problems: Mouth ulcers	1.7	2.8	7.8	2.7	1.5	2.8	1.2	1.2	0.4	1.3	-0.5
Medication for cholesterol	1.5	2.3	6.7	1.6	1.8	-0.3	-0.2	-0.4	-0.9	2.2	2.6
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.1	0.1	0.4	0.1	-0.4	0.3	-0.0	-0.0	0.6	-0.3	0.6
Back pain experienced in last month	0.8	1.1	3.0	0.4	1.4	-0.3	1.5	1.7	1.0	-0.6	-0.4
Mineral and other dietary supplements	0.4	0.6	2.4	0.4	-0.0	-0.1	0.6	1.0	0.8	1.5	-0.2
Breast cancer (self-reported)	2.8	3.4	14.3	0.5	2.3	-0.2	1.1	0.8	0.6	3.8	2.2
Asthma (self-reported)	0.3	0.6	2.5	0.7	-0.3	0.1	1.0	0.7	-1.6	-0.2	-0.5
Osteoporosis (self-reported)	0.9	1.2	3.8	-1.1	-1.5	-2.0	-0.7	-0.0	0.1	0.1	-1.1
Osteoarthritis (self-reported)	1.1	1.4	6.4	-1.3	-0.8	-1.0	-0.6	-0.9	2.5	-0.5	0.2
Medication: Aspirin	0.7	0.9	3.2	-1.0	-1.2	-0.7	0.3	0.0	-1.8	1.1	-0.4
Medication: Gliclazide	0.5	0.6	1.9	-0.5	-1.1	-1.4	-0.6	-0.4	-0.6	0.0	0.4
Illnesses of father: None of the above (group 1)	0.4	0.5	1.5	0.9	0.1	0.8	0.8	0.3	0.3	1.2	-0.2
Smoking status: Current	1.3	2.0	6.7	0.8	1.4	0.4	1.0	0.5	1.4	1.8	2.6
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.1	2.3	4.9	2.1	1.6	1.3	0.8	0.4	2.2	1.7	0.9
Whole body water mass	0.1	0.6	1.2	-0.9	-1.1	-1.1	-0.7	-0.7	-0.2	-0.6	-0.5
Leg predicted mass (right)	0.1	0.5	1.3	-0.5	-0.2	-0.9	-0.8	-1.1	0.0	0.8	0.4
Arm fat mass (left)	1.0	4.0	11.2	-1.7	-3.4	-1.3	-2.1	-2.2	1.2	-1.4	-1.9
Number of self-reported non-cancer illnesses	1.0	1.7	6.7	-0.7	-1.6	-1.1	0.0	-0.0	-1.1	-1.3	-2.6
Average weekly champagne plus white wine intake	0.4	0.5	1.5	-0.5	-0.3	-0.8	-1.0	-1.2	0.4	-0.6	0.5
Miserableness	0.3	0.6	1.4	-0.3	-0.5	0.8	1.1	1.2	-0.1	-0.9	0.1
Guilty feelings	0.5	0.8	3.2	-0.1	1.0	-0.5	-0.1	-0.2	-1.3	0.5	1.8
Wears glasses or contact lenses	0.8	0.9	3.8	0.2	1.5	0.9	0.7	0.2	-1.9	-0.2	0.6
Ever taken oral contraceptive pill	0.6	0.7	2.1	0.7	0.8	1.4	0.3	0.2	1.2	0.3	0.4
Hearing aid user	0.7	0.8	2.0	-0.8	0.2	-1.4	0.7	1.4	-0.6	-0.8	0.9
Mother’s age at death	0.6	0.8	2.1	-0.0	0.3	-1.1	-1.3	-0.6	1.5	-0.3	0.7
Financial situation satisfaction	2.2	2.7	11.2	-1.6	-1.2	-0.4	-0.1	-0.1	-3.3	-1.3	-2.2
Tinnitus: Yes, now most or all of the time	0.9	1.0	2.8	-0.5	-0.9	-0.7	-1.5	-1.7	-0.3	-0.1	1.3
Commuting to job workplace: Public transport	0.7	0.8	1.5	-1.2	-1.2	0.2	-1.1	-1.0	0.0	-0.0	-1.2
Eye problems/disorders: Glaucoma	3.7	4.4	6.6	1.8	-1.4	2.5	2.3	2.5	2.6	-1.7	-1.6
Medication: Blood pressure	1.6	3.0	6.3	-2.5	-2.1	-0.8	-0.4	0.2	0.7	-2.5	-2.5
Pain type(s) experienced in last month: Hip pain	0.7	0.8	1.6	-0.8	1.1	-1.3	-1.0	-0.8	-0.7	0.9	0.4
Supplements: Fish oil (including cod liver oil)	0.9	1.2	3.6	-0.4	-0.6	0.1	-1.6	-1.9	-0.1	-1.7	-0.3
High cholesterol (Self-reported)	1.2	2.1	9.2	-0.9	-2.1	0.7	0.5	0.8	-1.2	-0.1	-3.0
Medication: Bendroflumethiazide	1.7	2.5	7.9	-1.5	-1.6	-0.3	-0.1	-0.3	1.1	-2.8	-2.5
Medication: Paracetamol	0.5	0.8	2.5	-0.0	1.6	-1.2	0.5	0.8	-0.3	0.9	1.0
Medication: Lisinopril	1.6	2.1	10.8	-0.6	-1.3	0.3	0.4	0.5	-0.2	-1.9	-3.3
Medication: Atorvastatin	0.8	1.0	3.2	-1.3	-1.8	-0.3	-0.6	-0.3	-1.1	-0.2	-1.3
Illnesses of father: High blood pressure	0.7	0.9	2.1	0.5	1.5	0.1	0.7	0.4	-0.8	1.3	1.4
Alcohol drinker status: Never	0.6	0.7	2.4	0.0	-1.0	-0.2	1.1	0.8	0.5	-0.2	-1.6
Ever smoked	0.2	0.4	0.9	-0.7	0.1	0.7	1.0	0.9	0.3	-0.1	0.5
Basal metabolic rate	0.2	1.0	2.4	-1.2	-1.6	-1.1	-0.9	-0.9	-0.0	-0.9	-0.8
Leg fat percentage (left)	2.4	8.8	26.4	-2.9	-5.1	-1.7	-2.1	-1.9	1.1	-3.3	-3.5
Arm fat-free mass (left)	0.6	3.0	6.5	-2.1	-2.6	-1.4	-1.3	-1.2	-0.4	-2.3	-1.6
Number of operations (self-reported)	0.9	1.4	4.0	0.8	1.6	-0.1	-0.5	-1.1	0.2	1.6	2.0
Average weekly beer plus cider intake	1.2	1.7	4.5	-0.4	1.5	-1.4	-1.5	-1.3	0.1	2.1	0.6
Irritability	0.5	0.8	2.2	-1.0	-0.3	-1.1	0.5	0.4	-1.5	-1.1	-0.2
Risk taking	0.7	1.1	2.5	1.0	1.4	0.2	0.1	-0.3	-1.3	1.6	1.1
Ever had prostate specific antigen (PSA) test	0.2	0.3	1.1	0.1	1.1	-0.1	-0.4	-0.2	0.4	-0.2	0.8
Fractured/broken bones in last 5 years	0.8	1.0	2.3	-1.4	-0.7	-1.4	-0.3	-0.5	-1.5	0.3	-1.0
Age started oral contraceptive pill	1.9	2.4	6.6	-1.1	-2.6	-0.5	-0.9	-0.8	-0.7	-2.2	-2.0
Diastolic blood pressure, automated reading	0.2	0.7	3.8	-0.6	0.2	-0.5	-0.7	-0.9	-2.0	-0.1	-0.2
Ever depressed for a whole week	0.3	0.4	1.5	-0.6	1.2	0.0	0.7	0.2	-0.7	0.4	-0.6
Unable to work because of sickness or disability	0.3	0.4	1.1	-0.5	-0.1	-0.5	-1.0	-0.8	-0.5	0.6	-0.6
Commuting to job workplace: Cycle	0.2	0.3	0.8	0.9	0.6	0.8	-0.2	-0.3	-0.3	0.2	0.4
Myopia	1.3	1.8	5.0	-1.6	-1.2	-0.6	-0.9	-0.4	-2.2	-1.6	-1.3
Vascular/heart problems diagnosed by doctor	1.4	3.9	11.2	2.3	3.0	1.1	-0.0	-0.6	0.3	2.1	3.4
Cholesterol lowering medication	3.2	4.8	8.9	-2.6	-2.2	-1.8	-2.6	-2.0	-1.3	-1.2	-3.0
Medication: Omeprazole (e.g. Zanprol)	1.5	1.9	5.8	-0.8	-0.5	-1.8	-1.5	-1.6	2.4	-0.3	-0.6
Pain experienced in last month	0.3	0.6	3.4	0.5	-1.8	0.2	0.0	-0.1	0.7	-0.2	0.5
Supplements: Calcium	0.4	0.4	1.1	-0.4	-1.1	-0.9	0.1	0.3	0.4	-0.8	-0.6
Basal cell carcinoma (self-reported)	0.4	0.4	1.3	1.1	0.8	0.1	0.4	0.4	0.8	0.2	0.8
Heart attack/myocardial infarction (self-reported)	1.3	1.7	5.7	-1.5	-2.4	-0.8	-0.6	-0.6	-1.2	-1.3	-1.0
Deep venous thrombosis (DVT) (self-reported)	1.7	2.2	7.3	-1.5	-2.7	-1.6	-1.3	-1.1	-0.9	-1.4	0.3
Heart disease (siblings)	1.1	1.4	4.3	-1.3	-1.2	-0.4	-0.7	-0.1	-0.3	-2.1	-1.8
Alcohol drinker status: Previous	1.9	2.2	6.9	-1.6	-2.6	-1.2	-0.8	-0.3	1.2	-1.2	-1.7
Pack years of smoking	0.2	0.4	1.1	0.2	-0.8	-0.6	0.7	1.0	0.3	-0.3	0.5
Impedance of whole body	0.7	3.7	8.1	2.2	2.9	2.3	2.4	2.2	-0.8	0.4	0.9
Leg fat mass (left)	1.7	6.6	20.6	-2.5	-4.5	-1.4	-2.0	-2.0	0.8	-2.5	-2.9
Arm predicted mass (left)	0.5	2.6	5.7	-2.0	-2.4	-1.4	-1.1	-0.9	-0.4	-2.2	-1.5