Best TWAS P=1.07e-07 · Best GWAS P=1.68e-07 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Breast Mammary Tissue | PCYT1A | 0.11 | 0.03 | lasso | 3 | 0.00 | 0.3920 | 5.2 | -5.3 | 1.1e-07 | -0.96 | 0.01 | 0.88 | TRUE |
| 2 | GTEx | Breast Mammary Tissue (Male) | PCYT1A | 0.09 | 0.08 | enet | 9 | 0.00 | 0.2870 | 4.5 | -5.3 | 1.4e-07 | -0.87 | 0.02 | 0.58 | FALSE |
| 3 | GTEx | Stomach | SLC51A | 0.13 | 0.06 | enet | 12 | 0.03 | 0.0193 | 4.5 | -5.1 | 2.8e-07 | -0.86 | 0.01 | 0.96 | FALSE |
| 4 | The Cancer Genome Atlas | Brain Lower Grade Glioma | UBXN7 | 0.02 | 0.01 | blup | 45 | 0.02 | 0.0042 | 3.8 | -5.1 | 3.1e-07 | -0.76 | 0.01 | 0.27 | FALSE |