Best TWAS P=8.43e-09 · Best GWAS P=9.2e-07 conditioned to 2.81e-43
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | SLC26A1 | 0.12 | 0.06 | bslmm | 400 | 0.08 | 8.0e-10 | 4.4 | 5.3 | 8.8e-08 | -0.55 | 0.04 | 0.88 | TRUE |
| 2 | GTEx | Brain Cerebellar Hemisphere | SLC26A1 | 0.33 | 0.14 | lasso | 8 | 0.15 | 1.0e-04 | 4.4 | 5.2 | 1.6e-07 | -0.56 | 0.02 | 0.77 | TRUE |
| 3 | GTEx | Brain Cerebellum | SLC26A1 | 0.61 | 0.41 | enet | 22 | 0.46 | 2.1e-15 | 4.4 | 5.8 | 8.4e-09 | -0.67 | 0.03 | 0.91 | TRUE |
| 4 | GTEx | Esophagus Gastroesophageal Junction | SLC26A1 | 0.44 | 0.33 | lasso | 6 | 0.35 | 1.8e-13 | 4.4 | 5.2 | 1.7e-07 | -0.84 | 0.02 | 0.95 | TRUE |
| 5 | GTEx | Stomach | SLC26A1 | 0.26 | 0.17 | enet | 14 | 0.16 | 4.0e-08 | 4.4 | 5.3 | 1.1e-07 | -0.57 | 0.03 | 0.90 | TRUE |
| 6 | NTR | Blood | PCGF3 | 0.07 | 0.00 | enet | 33 | 0.02 | 7.7e-08 | 3.5 | 5.3 | 1.4e-07 | -0.38 | 0.17 | 0.50 | TRUE |
| 7 | The Cancer Genome Atlas | Breast Invasive Carcinoma | PCGF3 | 0.03 | 0.00 | blup | 69 | 0.01 | 3.7e-03 | 3.5 | 5.2 | 1.8e-07 | -0.39 | 0.00 | 0.03 | TRUE |