Best TWAS P=7.31e-08 · Best GWAS P=5.76e-07 conditioned to 0.713
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Whole Blood | HTT | 0.10 | 0.00 | enet | 15 | 0.03 | 1.4e-03 | 4.7 | 5.1 | 2.7e-07 | -0.58 | 0.05 | 0.66 | FALSE |
| 2 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | C4orf44 | 0.03 | 0.02 | blup | 42 | 0.02 | 8.0e-04 | -4.6 | 5.3 | 1.0e-07 | -0.65 | 0.01 | 0.94 | FALSE |
| 3 | The Cancer Genome Atlas | Lung Adenocarcinoma | C4orf44 | 0.03 | 0.04 | lasso | 4 | 0.05 | 2.9e-06 | -4.8 | 5.4 | 7.3e-08 | -0.70 | 0.01 | 0.98 | TRUE |
| 4 | The Cancer Genome Atlas | Soft Tissue Sarcoma | GRK4 | 0.08 | 0.07 | blup | 77 | 0.09 | 4.4e-06 | -4.4 | 5.2 | 2.2e-07 | -0.74 | 0.09 | 0.86 | TRUE |