Best TWAS P=1.09e-07 · Best GWAS P=3.06e-08 conditioned to 0.342
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Cells Transformed fibroblasts | SLC25A37 | 0.13 | 0.05 | lasso | 5 | 0.04 | 0.0003 | -5.5 | 5.3 | 1.2e-07 | -0.86 | 0.01 | 0.99 | TRUE |
2 | The Cancer Genome Atlas | Kidney Renal Papillary Cell Carcinoma | LOXL2 | 0.16 | 0.03 | lasso | 4 | 0.05 | 0.0012 | -4.7 | 5.3 | 1.1e-07 | -0.59 | 0.00 | 0.67 | TRUE |