Hub : Genes

SLC25A37

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 CommonMind Brain Pre-frontal Cortex 0.0820 0.0250 6.0e-05 0.048 0.042 0.038 0.046 0.053 1.6e-06 6.1e-06 1.7e-05 2.3e-06 4.8e-07
2 GTEx Brain Cerebellar Hemisphere 0.5270 0.1380 2.9e-03 -0.011 NA -0.004 NA 0.000 8.5e-01 NA 4.3e-01 NA 3.3e-01
3 GTEx Cells Transformed fibroblasts 0.1260 0.0420 6.5e-04 0.048 NA 0.026 NA 0.044 1.6e-04 NA 4.3e-03 NA 3.0e-04
4 ROSMAP Brain Pre-frontal Cortex 0.2747 0.0369 0.0e+00 0.356 0.289 0.367 0.359 0.366 1.1e-47 2.1e-37 1.5e-49 3.1e-48 2.5e-49
5 YFS Blood 0.1015 0.0180 0.0e+00 0.061 0.084 0.085 0.086 0.081 3.0e-19 5.5e-26 2.7e-26 1.2e-26 3.6e-25
6 TCGA Breast Invasive Carcinoma 0.0557 0.0197 4.3e-07 0.028 0.025 0.025 NA 0.023 1.3e-06 4.7e-06 4.9e-06 NA 1.3e-05
7 TCGA Head and Neck Squamous Cell Carcinoma 0.1099 0.0342 4.1e-09 0.095 0.079 0.076 NA 0.085 8.7e-11 3.5e-09 7.4e-09 NA 7.8e-10
8 TCGA Kidney Renal Clear Cell Carcinoma 0.0385 0.0191 3.9e-03 0.019 0.032 0.025 NA 0.033 2.9e-03 1.5e-04 7.2e-04 NA 1.1e-04
9 TCGA Kidney Renal Papillary Cell Carcinoma 0.1260 0.0590 2.5e-03 -0.001 0.028 0.003 NA 0.008 3.5e-01 9.4e-03 2.1e-01 NA 1.1e-01

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
Bipolar Disorder (2018) 0.1 0.2 1.1 -0.0 -0.2 0.2 0.2 0.2 1.0 0.3 0.2 -0.2
Bipolar Disorder or Schizophrenia 0.3 0.8 1.6 -0.9 -1.1 -1.0 0.4 0.5 1.3 1.2 0.8 0.7
Depressed Affect (Nagel 2018) 1.4 2.9 9.7 0.2 1.7 1.2 3.1 2.4 0.1 -0.9 1.1 -1.9
Depression (Nagel 2018) 1.0 1.4 4.6 -0.4 0.5 0.2 2.2 1.6 0.6 0.2 1.4 -1.7
Intelligence (Savage-Jansen 2018) 0.2 0.6 4.0 -0.5 2.0 -0.2 -0.1 0.4 -0.9 0.0 0.2 0.6
Neuroticism (Nagel 2018) 2.3 5.5 17.9 -1.8 1.7 -0.8 4.2 3.8 0.6 0.9 2.8 -1.4
Schizophrenia (2018) 0.5 1.0 2.2 -1.1 -1.0 -1.5 0.4 0.5 0.8 1.3 0.8 1.1
Schizophrenia vs Biploar Disorder 0.9 1.1 5.0 -0.4 0.4 -1.4 -0.8 -1.2 -0.7 0.7 0.1 2.2
Worry (Nagel 2018) 1.5 3.2 8.9 -1.8 1.1 -1.4 3.0 2.9 -0.3 0.8 2.1 -0.6
Alzheimer’s Disease (in mother) 0.6 0.8 4.7 1.0 0.2 0.2 0.1 0.4 2.2 0.7 0.4 0.2
Alzheimer’s Disease (in father) 1.2 1.3 3.4 -0.6 1.9 0.7 0.9 0.4 -1.6 -1.1 -0.4 -1.5
Alzheimer’s Disease (including proxy) 0.2 0.3 1.6 0.5 0.8 0.3 -0.0 -0.1 1.3 0.3 0.0 -0.2
Crohns Disease (2017) 0.1 0.3 0.9 0.7 -0.2 -0.2 -1.0 -0.7 0.2 -0.1 -0.5 0.7
Irritable Bowel Disease (IBD) 0.8 1.9 6.2 2.5 1.4 1.8 -0.2 -0.8 0.2 -1.6 -1.3 -0.8
Ulcerative Colitis (UC) 1.5 2.7 6.7 2.6 1.9 2.5 0.3 -0.5 -0.2 -2.0 -1.3 -1.4
Major Depression (MDD) 1.4 1.7 6.7 -1.3 0.6 -0.4 1.8 2.6 0.5 1.1 1.4 -0.1
Reaction Time 0.3 0.5 1.9 0.1 -1.4 0.5 0.5 0.2 -0.7 -0.7 -0.7 -0.7
Verbal and Numeric Reasoning (VNR) 0.2 0.4 0.9 -0.8 0.5 -0.7 -0.5 -0.7 0.1 0.3 0.4 0.9
Breast Cancer 1.9 4.5 9.0 -1.0 -2.6 -2.9 -3.0 -2.4 0.6 1.9 0.0 2.3
Ovarian Cancer 1.6 2.1 6.4 -0.9 0.3 -1.0 0.9 -0.1 2.5 1.9 2.2 -1.1
Prostate Cancer 5.0 7.0 21.8 -3.4 1.0 -0.6 4.7 3.5 -3.5 -0.5 2.0 -0.4
Age at First Birth 0.4 0.6 2.0 -1.4 -0.3 -1.0 -0.3 -0.7 -0.0 0.6 0.4 1.1
Bipolar Disorder (2011) 0.9 0.9 1.7 -0.4 -1.0 -1.0 -0.7 -0.8 1.1 1.2 0.2 1.3
Body Mass Index (BMI) (2010) 3.9 5.4 9.8 3.1 0.3 3.1 -1.8 -1.1 -1.8 -3.0 -2.8 -2.1
Coronary Artery Disease (CAD) 0.3 0.3 1.5 -0.0 -0.4 -0.0 0.0 0.2 1.2 0.6 0.4 0.7
Crohns Disease (2012) 0.1 0.2 0.6 0.2 -0.1 -0.5 -0.6 -0.2 -0.7 0.0 -0.1 0.8
Mean Putamen Volume 0.3 0.4 1.6 0.3 0.2 0.5 0.9 1.3 0.5 0.1 0.6 -0.1
Fasting Glucose 0.8 0.9 3.3 0.6 0.0 0.2 -1.8 -1.2 0.3 -0.2 -0.7 -1.5
HbA1C 0.8 0.9 2.3 0.0 1.0 -0.1 1.5 1.2 1.3 0.4 0.9 -0.7
HDL Cholesterol 0.7 1.1 2.4 0.8 -0.0 1.3 -0.5 -0.2 -1.5 -1.5 -1.0 -1.3
LDL Cholesterol 1.3 2.1 6.2 1.9 -1.2 2.5 0.9 1.3 1.5 -1.1 -0.3 -1.4
Lupus 0.7 1.0 2.1 1.1 -1.1 0.4 -0.8 -1.1 -1.5 -1.0 -1.2 -0.5
Neuroticism (2016) 0.8 1.2 3.2 0.8 1.4 0.8 1.2 1.1 1.8 0.7 0.9 -0.5
Primary Biliary Cirrhosis 3.3 4.7 12.0 3.2 0.2 2.1 -2.0 -3.5 2.1 -1.1 -2.0 -1.4
Rheumatoid Arthritis 0.4 0.5 1.3 0.7 -1.2 0.5 -0.6 -0.7 -0.7 -0.6 -0.7 0.4
Schizophrenia (2014) 0.2 0.5 1.9 0.3 -1.4 -0.6 -0.4 -0.3 0.9 0.6 0.1 0.5
Triglycerides 0.6 0.9 2.9 1.7 1.2 0.8 -1.0 -0.2 0.5 -0.6 -0.9 -0.8
Type 2 Diabetes (T2D) (2012) 2.1 2.4 5.3 1.6 0.8 1.9 -0.7 -2.3 -1.3 -1.9 -1.9 -0.5
Ulcerative Colitis 0.6 0.9 2.2 1.5 1.3 1.2 0.7 -0.2 0.0 -1.0 -0.5 -1.1
Blood Eosinophil Count 0.8 6.2 21.2 3.3 -1.2 3.2 -1.7 -2.4 4.6 -0.6 -1.3 1.1
Blood Platelet Count 1.7 19.2 37.0 4.1 -1.0 5.1 -5.4 -4.6 -2.6 -5.7 -6.1 -1.3
Blood Red Count 2.8 27.1 110.2 0.0 0.9 2.8 10.5 8.7 1.1 -1.6 3.2 -6.0
Blood White Count 0.3 2.6 8.0 -1.3 -2.1 -1.5 -1.2 -0.7 0.5 1.9 1.2 2.8
Heel T-Score 0.3 2.5 8.1 0.4 0.2 0.2 -2.7 -2.8 1.5 0.9 -0.8 1.7
BMI 2.9 16.9 37.8 5.4 -1.5 6.1 -2.6 -2.5 -2.3 -5.7 -5.1 -2.4
Height 1.4 26.9 65.9 3.6 2.6 8.1 5.5 3.8 -2.4 -8.1 -2.5 -5.9
Waist Hip Ratio (WHR) 0.3 1.2 3.2 1.0 1.7 -0.5 -1.3 -0.6 1.8 1.0 -0.1 -0.3
Systolic Blood Pressure 3.8 19.0 44.9 -3.8 1.2 -4.8 1.9 0.7 4.4 6.7 5.5 5.8
Smoking Status 0.4 0.9 2.5 -1.6 -0.5 -1.0 1.1 -0.0 -0.8 0.4 1.5 -0.1
Allergy or Eczema 1.2 3.2 10.0 1.4 0.3 1.7 -0.5 1.7 -1.8 -2.0 -1.7 -3.2
Cardiovascular Disease 2.6 8.4 17.3 -2.4 -2.5 -3.1 0.9 -0.6 3.2 3.9 3.2 4.2
Hypothyroidism (self reported) 7.1 16.2 30.4 5.1 0.0 5.1 -3.5 -2.5 -3.0 -5.5 -5.5 -2.4
Respiratory disease 1.2 2.8 6.2 -2.5 -0.1 -2.0 2.1 1.9 -1.7 0.9 1.5 0.7
Type 2 Diabetes (T2D) (2018) 0.2 0.3 1.0 -0.3 -0.1 -0.5 -0.6 -1.0 -0.7 0.2 -0.3 0.5
Lung FEV1/FVC ratio 1.5 7.4 12.2 3.0 -3.3 2.7 -3.2 -3.5 0.3 -2.2 -3.0 -1.9
Lung FVC 0.4 2.1 9.4 -0.8 1.8 0.3 3.1 1.8 -0.9 -0.8 0.5 -0.7
Neuroticism 1.8 4.3 11.1 -1.5 0.9 -1.5 3.3 2.6 2.0 1.8 2.9 0.1
Chronotype (morning person) 0.4 0.8 3.1 0.6 1.3 0.4 0.5 1.0 0.9 -0.1 -0.1 -1.8
Hair Pigment 0.0 0.3 1.0 0.2 0.5 0.0 -1.0 -0.1 -0.0 -0.5 -1.0 -0.8
Tanning 0.1 0.9 2.9 -1.7 -0.1 -1.1 1.4 0.0 -0.1 0.4 1.2 1.0
Hand grip strength (left) 1.5 4.1 11.6 0.9 -1.7 0.2 -3.4 -2.9 -2.5 -1.1 -2.2 1.0
Number of treatments/medications taken 0.9 1.6 2.9 -1.4 -0.7 -1.4 1.2 1.3 0.1 1.3 1.7 1.6
Average weekly spirits intake 0.9 1.1 3.8 -0.7 1.0 -0.4 1.0 2.0 -1.8 -0.3 0.5 -0.6
Sensitivity / hurt feelings 1.0 1.7 5.7 -1.3 -0.6 -0.5 2.4 2.1 0.1 0.3 1.3 -0.9
Frequency of depressed mood in last 2 weeks 1.5 2.1 6.0 -0.6 0.6 -0.2 2.5 2.2 1.0 1.0 1.9 -1.3
Hearing difficulty/problems: Yes 1.1 1.7 6.8 0.2 -1.5 -0.6 0.6 1.1 2.6 1.2 1.1 -1.0
Relative age of first facial hair 1.5 3.2 6.4 -2.0 -0.3 -1.9 1.8 0.5 1.9 2.3 2.5 1.3
Other serious medical condition/disability diagnosed by doctor 0.6 0.7 1.7 0.5 0.3 0.8 -0.0 1.2 -1.3 -1.1 -0.3 -1.2
Ever used hormone-replacement therapy (HRT) 0.7 0.9 2.4 1.1 -0.0 1.0 -0.3 -0.5 -1.0 -1.6 -1.0 -1.2
Ever had hysterectomy (womb removed) 1.2 1.3 3.0 0.6 1.1 1.2 0.2 -0.2 -1.1 -1.7 -1.3 -1.7
Systolic blood pressure, automated reading 2.0 5.8 12.2 -2.4 1.1 -2.9 0.9 0.1 2.2 3.5 2.8 3.4
Eye problems/disorders: Diabetes related eye disease 0.2 0.3 0.7 0.4 0.6 0.5 0.9 0.0 0.1 -0.6 -0.3 -0.5
Angina 0.2 0.3 0.7 0.1 -0.4 0.5 0.0 -0.6 -0.6 -0.8 -0.8 0.0
Medication for hormone replacement therapy 0.3 0.3 1.1 -0.3 -0.7 -0.2 -0.3 -0.4 -1.0 -0.1 -0.2 0.8
Vitamin and mineral supplements 1.0 1.3 4.2 1.1 -0.9 0.4 -1.7 -2.1 0.9 0.3 -0.6 1.3
Supplements: Zinc 1.0 1.0 3.7 1.2 -0.2 1.0 0.3 0.6 1.3 -0.8 -0.7 -1.9
Medication: Co-codamol 0.4 0.4 0.7 -0.7 -0.8 -0.8 -0.2 -0.6 0.8 0.7 -0.0 0.6
Medication: Metformin 0.6 0.8 1.8 -1.3 -0.2 -1.2 -0.1 0.5 -1.2 1.1 0.7 0.5
Diabetes (father) 0.3 0.4 0.8 0.9 0.3 0.2 -0.0 0.8 -0.7 -0.6 -0.5 -0.8
Diabetes (mother) 0.5 0.6 2.9 0.3 0.1 0.9 0.6 0.9 0.6 -0.3 0.4 -1.7
Severe depression (siblings) 1.4 1.6 3.2 -1.3 1.2 -0.8 1.8 1.8 0.3 1.1 1.6 -0.4
Pack years adult smoking proportion 2.3 3.6 7.4 -2.1 0.7 -2.7 1.0 1.4 0.8 2.5 2.4 2.1
Impedance of leg (right) 0.6 2.8 6.2 -1.9 1.2 -1.5 2.5 1.8 1.5 1.4 2.2 -0.1
Leg fat-free mass (left) 2.0 10.8 30.5 4.1 -0.1 5.5 -0.2 -0.2 -2.5 -5.1 -3.4 -2.4
Trunk fat percentage 3.0 11.9 31.7 4.5 0.8 5.6 -0.9 -0.7 -1.4 -4.8 -3.4 -4.1
Hand grip strength (right) 1.7 4.7 9.1 1.2 -1.5 1.2 -3.0 -3.0 -2.7 -1.9 -2.7 1.0
Townsend deprivation index at recruitment 1.9 2.7 11.9 -0.5 -0.9 0.2 2.7 3.5 0.3 0.1 1.4 -1.5
Current tobacco smoking 0.5 0.8 1.8 -0.7 -1.0 -0.5 1.2 0.8 0.0 0.2 1.3 -1.1
Average weekly fortified wine intake 1.3 1.6 8.1 0.8 -0.9 0.4 -1.6 -2.9 -0.4 0.3 -0.7 0.9
Maternal smoking around birth 0.5 0.7 2.2 -0.5 -1.5 -0.6 1.1 1.2 0.2 0.4 0.6 0.5
Fed-up feelings 0.7 1.2 4.0 0.7 1.0 1.0 1.9 2.0 -0.0 -0.6 0.7 -0.5
Frequency of unenthusiasm / disinterest in last 2 weeks 1.1 1.4 5.2 -0.9 -0.2 -0.6 2.3 1.7 0.4 0.9 1.5 -0.6
Relative age voice broke 2.6 3.9 9.8 -1.9 -0.2 -2.1 1.5 0.6 3.1 2.7 2.5 1.1
Taking other prescription medications 0.5 0.8 3.4 -1.0 0.0 -0.0 1.8 1.2 -0.7 -0.5 0.8 0.4
Age when periods started (menarche) 0.1 0.3 1.9 0.4 1.4 0.2 0.3 0.3 -0.3 -0.6 -0.0 -0.6
Bilateral oophorectomy (both ovaries removed) 0.6 0.7 1.6 0.7 0.3 1.2 -0.2 -0.8 -0.4 -1.3 -0.9 -1.1
Heel bone mineral density (BMD) T-score, automated (left) 0.3 0.7 2.3 -0.0 1.5 0.1 -1.1 -0.8 -1.3 -0.4 -0.7 0.5
Tinnitus: Yes, but not now, but have in the past 0.2 0.3 1.5 -0.2 -1.2 -0.2 -0.6 0.4 0.4 0.3 -0.0 0.1
Qualifications: CSEs or equivalent 0.5 0.7 1.6 1.0 -1.1 1.0 0.1 -0.0 1.3 0.3 0.2 -1.1
Serious illness, injury or assault to yourself 0.6 0.7 2.4 -0.6 0.1 -0.2 1.5 1.6 -0.8 -0.2 0.7 -0.4
High blood pressure 4.3 12.1 24.2 -3.4 -2.5 -4.3 1.2 -0.3 3.0 4.9 4.2 4.4
Hayfever, allergic rhinitis or eczema 0.9 1.9 5.1 1.2 -0.1 1.1 -0.4 1.7 -1.5 -1.5 -1.4 -2.2
Multivitamins +/- minerals 0.4 0.5 1.4 -0.4 0.3 0.4 0.6 0.5 -0.7 -1.0 -0.4 -1.2
Stomach or abdominal pain in last month 0.4 0.4 0.8 -0.9 -0.5 -0.8 0.8 0.6 -0.1 0.7 0.9 0.1
Supplements: Glucosamine 1.3 1.6 3.1 1.0 0.7 1.1 -1.3 -0.6 -1.3 -1.6 -1.6 -1.7
Diverticular disease/diverticulitis (self-reported) 0.7 0.9 3.8 -0.3 -0.1 -0.1 0.0 1.2 -1.9 -0.6 -0.5 -1.4
Medication: Atenolol 2.9 3.6 10.1 2.2 0.4 1.2 -3.2 -3.2 -0.1 -1.2 -2.1 0.6
Medication: Levothyroxine sodium 3.2 5.4 10.6 2.8 -0.3 2.8 -1.9 -1.8 -2.1 -3.3 -3.1 -1.1
Sitting height 1.2 8.4 20.8 1.7 0.4 4.0 3.2 2.8 -2.9 -4.6 -1.6 -2.6
Chronic bronchitis/emphysema (father) 1.1 1.3 3.2 -1.4 -1.0 -1.7 0.6 0.5 -0.0 1.4 1.8 0.4
High blood pressure (mother) 0.6 0.8 3.8 -0.4 -0.6 -0.3 -2.0 -1.4 -0.1 0.2 -0.3 0.8
Body mass index (BMI) 2.2 9.6 21.5 4.4 -0.1 4.6 -1.9 -1.6 -1.9 -4.2 -3.7 -2.0
Impedance of leg (left) 0.6 3.1 5.9 -2.0 1.2 -1.7 2.2 1.8 1.5 1.9 2.4 -0.1
Leg predicted mass (left) 2.1 10.9 31.0 4.2 -0.1 5.6 -0.2 -0.2 -2.5 -5.1 -3.4 -2.4
Trunk fat mass 3.7 15.8 42.5 5.2 0.6 6.5 -0.8 -0.7 -2.0 -5.8 -4.1 -4.2
Waist circumference 3.2 11.8 28.0 5.0 0.4 5.3 -2.2 -1.6 -1.0 -4.5 -4.0 -2.8
Number of incorrect matches in round 1.0 1.7 4.4 -1.9 0.1 -1.7 1.0 0.0 0.9 1.5 0.5 2.1
Past tobacco smoking 0.2 0.4 1.5 1.2 -0.0 0.5 -0.7 0.3 1.2 0.1 -0.3 -0.5
Alcohol usually taken with meals 0.5 0.7 2.2 0.1 -0.4 -0.7 -1.5 -0.8 0.9 1.1 0.4 1.0
Nervous feelings 0.4 0.7 2.5 -0.9 0.3 -0.4 1.1 1.6 -0.3 0.2 0.5 -1.1
Frequency of tenseness / restlessness in last 2 weeks 1.5 2.4 6.7 -0.3 -0.1 -0.7 2.3 1.9 2.6 1.3 1.8 -0.2
Hearing difficulty/problems with background noise 0.4 0.7 2.0 0.9 -1.3 0.4 -0.7 -0.1 0.9 -0.1 -0.2 -1.4
Hair/balding pattern: Pattern 2 0.8 1.0 2.0 1.0 1.2 1.1 0.4 1.2 -0.8 -1.4 -0.6 -0.7
Had menopause 0.6 0.8 3.2 0.5 0.3 -0.3 -0.3 -1.8 1.5 0.9 0.6 0.2
Had other major operations 0.6 0.7 2.9 1.7 0.0 0.3 -0.6 0.2 1.6 0.4 -0.3 -0.6
Forced vital capacity (FVC) 0.8 3.0 7.7 1.1 0.9 2.8 2.4 1.5 -0.9 -2.6 -0.6 -1.2
Heel bone mineral density (BMD) T-score, automated (right) 0.4 0.9 2.3 0.7 0.8 0.9 -1.1 -0.4 -1.5 -1.1 -0.8 -0.7
Ever unenthusiastic/disinterested for a whole week 0.9 1.2 2.7 -0.9 -1.4 -0.9 1.6 1.4 -0.6 0.6 1.2 -0.0
Qualifications: None of the above 0.4 0.8 1.9 1.0 0.8 0.2 1.4 1.1 1.3 -0.2 0.1 -0.8
Financial difficulties in last 2 years 0.4 0.5 2.3 1.0 -0.6 0.4 0.6 0.7 -0.4 -0.3 0.0 -1.5
Mouth/teeth dental problems 0.8 1.2 5.4 0.2 -2.3 -0.7 -0.6 -1.2 1.2 0.8 0.3 1.1
Heart attack 1.4 1.8 10.6 0.4 0.2 -0.3 -1.1 -1.4 3.3 1.2 0.2 0.9
Allergy 0.7 1.6 2.5 -1.3 0.3 -1.1 0.5 -1.4 1.3 1.6 1.5 1.5
Pain all over the body in last month 0.0 0.0 0.1 0.2 0.0 0.0 0.1 -0.1 -0.0 -0.1 -0.2 -0.3
Diabetes (self-reported) 0.2 0.2 0.7 -0.5 0.2 -0.6 0.1 -0.8 0.1 0.8 0.4 -0.2
Hayfever/allergic rhinitis (self-reported) 1.0 1.4 2.8 1.4 1.0 1.7 -0.5 0.2 -0.6 -1.4 -1.5 -1.2
Medication: Ramipril 1.8 2.4 5.6 0.5 1.5 -0.9 -1.0 -1.8 2.2 1.7 0.7 2.4
Medication: Simvastatin 0.6 0.9 3.5 1.0 -0.4 0.7 -1.0 -1.9 -0.5 -0.8 -1.0 -0.2
Fluid intelligence score 0.1 0.3 1.1 -0.7 0.2 -0.3 0.1 0.3 -0.8 -0.3 0.3 1.1
Illnesses of siblings 1.2 1.7 3.3 1.4 -0.6 0.7 -1.8 -1.8 -1.4 -1.3 -1.7 -0.2
Neuroticism score 1.3 2.8 8.4 -0.8 0.4 -0.7 2.9 2.6 1.4 1.2 2.2 -0.5
Weight 3.4 16.5 44.5 5.2 0.4 6.7 -0.5 -0.4 -2.9 -6.2 -4.3 -3.2
Impedance of arm (right) 0.7 3.1 4.9 -1.8 1.6 -1.1 1.9 2.2 1.9 1.6 2.1 -1.1
Arm fat percentage (right) 2.9 11.3 29.6 4.6 0.4 5.4 -1.4 -0.7 -1.1 -4.5 -3.5 -3.7
Trunk fat-free mass 1.6 9.0 25.3 3.6 -0.5 5.0 0.9 0.0 -2.5 -4.9 -2.8 -1.9
Hip circumference 3.5 15.1 40.6 5.4 0.2 6.4 -1.5 -0.9 -1.8 -5.7 -4.4 -2.9
Time employed in main current job 0.4 0.4 1.3 -0.7 0.3 -0.9 -0.2 0.5 -1.0 0.1 0.2 1.2
Alcohol intake versus 10 years previously 1.2 1.7 4.2 1.5 1.5 1.6 0.5 -0.9 -2.0 -1.7 -0.8 -0.3
Father’s age at death 1.9 2.5 5.7 2.4 0.1 2.1 -0.6 -0.6 -0.5 -2.1 -1.8 -2.1
Worrier / anxious feelings 0.9 1.8 3.6 -1.4 0.2 -1.9 1.5 1.7 -0.9 0.9 1.5 1.1
Frequency of tiredness / lethargy in last 2 weeks 1.1 1.8 6.3 -0.4 1.3 -0.0 2.3 2.5 -0.0 0.0 1.2 -1.0
Falls in the last year 1.0 1.3 2.7 -1.7 -0.9 -1.2 0.6 1.5 -0.5 1.0 1.4 1.2
Hair/balding pattern: Pattern 3 0.1 0.2 0.6 0.1 -0.2 -0.1 -0.8 -0.7 0.5 0.3 -0.3 -0.3
Number of live births 0.9 1.3 4.4 -0.3 0.8 -0.9 0.9 0.2 2.1 1.5 1.5 -0.1
Forced expiratory volume in 1-second (FEV1) 1.1 3.8 12.1 1.6 0.2 3.5 1.4 0.7 -1.2 -3.2 -1.5 -1.8
Pulse rate 0.5 0.9 3.0 -0.8 -0.8 -1.7 -0.4 -0.5 -0.2 1.4 0.8 0.8
Happiness 4.0 4.8 10.0 -2.3 -0.2 -2.4 3.2 3.0 -0.1 2.2 2.9 0.5
Noisy workplace 1.2 1.5 3.0 1.5 -0.8 1.4 0.2 1.3 0.3 -1.5 -1.2 -1.7
Qualifications: A levels/AS levels or equivalent 0.1 0.2 1.0 0.2 -0.1 0.1 -1.0 0.1 0.1 -0.2 -0.4 -0.3
Serious illness, injury or assault of a close relative in last 2 years 0.3 0.4 0.8 -0.2 0.6 0.5 0.8 0.9 -0.6 -0.6 -0.1 -0.8
Mouth/teeth dental problems: Dentures 0.0 0.1 0.4 -0.1 0.6 -0.3 -0.1 0.2 -0.1 -0.0 -0.0 -0.2
Asthma 0.9 1.7 4.1 -1.6 -0.3 -2.0 1.3 1.5 -0.3 1.3 1.1 1.2
Medication: Ibuprofen (e.g. Nurofen) 0.4 0.5 1.6 0.9 0.5 0.8 0.1 1.3 0.8 -0.5 -0.4 -0.4
Medication: Cholesterol lowering 0.5 0.7 3.9 -0.4 -2.0 -0.3 -0.3 -0.5 1.1 0.7 0.5 0.2
Depression (self-reported) 0.5 0.6 1.7 -0.4 -1.3 -0.1 1.3 0.8 -0.1 0.4 0.8 -0.2
Medication: Lansoprazole 2.7 3.1 9.3 -1.7 0.2 -2.0 0.9 -1.2 1.0 2.0 2.1 3.1
Prospective memory result 0.5 0.6 3.1 0.0 1.8 -0.4 1.0 0.5 0.1 0.4 0.4 -0.5
Lung cancer (father) 0.8 0.9 3.0 -0.1 1.6 0.8 1.7 1.1 0.4 -0.1 0.8 0.1
Illnesses of mother 0.6 0.7 4.6 -0.3 0.6 -0.0 2.1 0.7 -0.3 0.2 0.8 -0.1
Forced expiratory volume in 1-second (FEV1), Best measure 0.9 2.8 10.4 1.9 -0.2 3.2 1.0 0.3 -0.2 -2.6 -1.3 -1.5
Pulse wave Arterial Stiffness index 0.5 0.6 1.8 0.0 0.6 -0.6 1.1 -0.8 0.6 0.9 1.3 0.1
Impedance of arm (left) 0.7 3.2 5.8 -2.0 1.4 -1.7 1.7 1.7 1.9 2.1 2.4 -0.6
Arm fat mass (right) 3.2 13.2 35.4 5.0 0.3 5.9 -1.1 -0.6 -1.8 -5.2 -3.8 -3.6
Trunk predicted mass 1.5 8.7 24.3 3.5 -0.5 4.9 0.9 0.1 -2.5 -4.8 -2.7 -1.9
Standing height 0.9 8.8 22.7 2.1 0.9 4.7 3.1 2.1 -2.4 -4.8 -1.5 -2.8
Length of working week for main job 0.6 0.6 1.0 -0.6 -0.7 -0.9 0.9 1.0 0.5 0.8 0.8 0.8
Exposure to tobacco smoke at home 0.7 0.8 2.4 -0.2 -1.4 -0.7 -0.3 -0.8 1.0 0.6 0.1 1.5
Breastfed as a baby 0.8 1.0 4.2 -0.5 -0.4 0.2 -1.1 -0.5 -2.1 -1.2 -1.2 0.1
Tense / ‘highly strung’ 1.7 2.8 5.6 -1.7 0.1 -2.1 1.5 1.6 1.2 2.4 2.4 0.3
Seen doctor (GP) for nerves, anxiety, tension or depression 0.5 0.8 3.2 -0.0 0.5 0.7 1.8 0.8 -1.3 -0.8 0.6 -0.3
Hair/balding pattern: Pattern 4 1.4 3.4 8.4 0.4 -0.7 0.6 -2.9 -2.7 -2.5 -1.4 -2.4 0.5
Birth weight of first child 6.4 11.6 28.3 5.3 0.4 4.9 -2.0 -2.4 1.6 -3.6 -4.0 -3.3
Peak expiratory flow (PEF) 0.3 0.7 2.2 -0.5 0.5 0.6 1.0 -0.0 -1.3 -0.5 0.5 1.5
Pulse wave reflection index 0.4 0.5 1.2 0.3 0.8 0.7 0.7 -1.1 0.6 -0.2 0.5 -0.7
Ever highly irritable/argumentative for 2 days 0.4 0.5 1.5 -0.3 -1.1 -0.9 -1.2 -0.2 -0.0 0.6 0.2 -0.8
Loud music exposure frequency 1.6 1.8 4.4 1.9 -1.5 0.5 -1.4 -2.1 1.9 -0.1 -0.6 -0.1
Qualifications: O levels/GCSEs or equivalent 0.7 1.1 3.0 0.8 1.0 1.5 -0.5 -0.6 0.0 -1.1 -1.1 -1.7
Mouth/teeth dental problems: Bleeding gums 1.5 2.0 7.3 -0.7 0.9 0.5 2.7 2.2 -0.1 -0.0 1.5 -1.3
Blood clot in the leg (DVT) 0.9 1.1 2.6 1.3 -1.4 1.6 -0.4 -0.7 0.4 -0.9 -0.7 -1.4
Medication: Paracetamol 0.7 1.2 3.4 -0.6 -0.6 -0.9 0.7 0.8 1.8 1.7 1.3 0.7
Headache pain in last month 0.8 1.4 2.4 -1.0 -1.6 -0.9 1.4 1.5 0.5 1.2 1.5 -0.6
Medication for cholesterol, blood pressure or diabetes 1.8 2.9 5.3 0.9 2.3 1.6 0.6 1.3 -2.1 -2.3 -1.5 -2.0
Glaucoma (self-reported) 0.8 0.9 3.2 0.2 -1.8 -0.3 -0.4 0.9 1.7 0.8 0.5 0.2
Gout (self-reported) 1.3 1.8 4.8 1.4 2.2 1.7 -0.9 -0.9 1.2 -0.9 -1.2 -1.3
Hypothyroidism/myxoedema (self-reported) 2.6 5.0 10.9 2.7 0.2 2.9 -1.7 -1.0 -2.0 -3.3 -3.0 -1.3
Medication: Amlodipine 3.1 4.3 8.3 -1.6 -2.6 -2.4 0.4 -0.3 2.0 2.9 2.1 2.7
Medication: Ventolin 100micrograms inhaler 0.2 0.3 0.8 -0.8 0.9 -0.7 0.3 0.3 0.1 0.4 0.3 0.6
Birth weight 4.8 10.4 19.6 4.2 0.8 4.0 -3.5 -2.4 -1.2 -4.2 -4.4 -1.5
Chronic bronchitis/emphysema (mother) 1.6 1.8 6.5 -2.5 -0.2 -1.4 0.8 1.1 -0.3 0.8 0.7 2.2
High blood pressure (siblings) 1.8 2.6 6.8 -2.6 0.1 -2.1 0.9 0.8 0.4 2.0 2.0 1.7
Forced vital capacity (FVC), Best measure 0.7 2.5 6.8 1.0 0.6 2.6 2.5 1.6 -0.2 -2.2 -0.3 -1.0
Body fat percentage 2.8 11.1 29.4 4.5 0.7 5.4 -0.8 -0.5 -1.3 -4.7 -3.4 -3.8
Leg fat percentage (right) 2.4 8.6 22.7 4.1 0.6 4.8 -0.4 -0.5 -1.4 -4.3 -3.1 -2.7
Arm fat-free mass (right) 2.0 10.2 27.3 4.2 -0.8 5.2 0.4 -0.3 -2.7 -5.0 -3.1 -2.0
Exposure to tobacco smoke outside home 0.3 0.4 1.4 0.6 -1.2 0.1 0.5 0.0 0.8 0.4 0.6 -0.5
Comparative body size at age 10 0.5 1.3 3.6 1.5 -1.9 0.5 -1.5 -1.0 0.9 0.1 -0.9 -0.6
Number of full brothers 0.8 1.0 2.4 1.4 -0.4 1.4 0.4 0.7 1.2 -0.6 -0.5 -1.6
Worry too long after embarrassment 2.4 4.1 8.2 -2.2 0.6 -1.4 2.6 2.1 2.0 2.2 2.9 0.9
Seen a psychiatrist for nerves, anxiety, tension or depression 1.5 1.9 7.6 -0.1 1.9 1.3 2.8 1.0 0.8 -0.6 0.9 -1.3
Wheeze or whistling in the chest in last year 1.5 2.6 7.2 -2.2 -0.8 -1.6 1.3 2.7 0.4 1.7 1.8 0.4
Number of children fathered 1.8 2.1 5.0 -2.2 0.6 -2.0 0.5 0.3 0.6 2.0 1.5 1.5
Reason for reducing amount of alcohol drunk: Health precaution 1.9 2.3 4.5 -1.3 -1.9 -1.7 0.6 0.7 1.5 1.6 1.4 2.1
Age at first live birth 0.6 1.1 3.5 -0.8 -1.1 -0.3 -1.3 -1.3 -0.3 0.1 -0.8 1.9
Pulse wave peak to peak time 0.6 0.8 2.1 0.1 -0.7 0.8 -0.9 0.8 -0.8 -1.2 -1.5 -0.1
Health satisfaction 0.8 1.0 2.1 -0.4 -1.0 -1.4 1.0 0.8 0.5 1.4 1.3 0.4
Shortness of breath walking on level ground 0.4 0.5 1.8 0.7 0.2 0.8 0.9 0.3 -0.7 -0.5 -0.1 -1.4
Qualifications: College or University degree 0.2 0.5 1.6 -1.0 -1.1 -0.5 0.4 0.5 -1.3 0.3 0.4 0.2
Eye problems/disorders: None of the above 0.2 0.2 0.6 0.4 0.8 0.1 -0.0 -0.5 0.7 0.1 -0.0 -0.4
Mouth/teeth dental problems: Loose teeth 1.0 1.1 3.5 1.4 -0.0 1.1 0.4 1.4 -0.5 -1.1 -0.5 -1.9
Emphysema/chronic bronchitis 0.2 0.2 0.9 -0.5 0.0 -0.1 -0.5 0.0 -0.9 -0.7 -0.4 0.0
Medication for pain relief, constipation, heartburn 0.2 0.3 1.1 -0.0 0.8 0.1 0.0 -1.0 -0.8 -0.3 -0.3 -0.5
Neck or shoulder pain in last month 0.5 0.6 3.1 0.1 0.3 -0.4 0.5 0.1 1.8 1.1 0.9 0.5
Medication: Blood pressure 2.9 5.1 9.1 -1.4 -2.5 -2.4 -1.0 -1.6 2.7 3.0 1.8 3.0
Angina (self-reported) 0.3 0.4 1.2 0.1 -0.5 0.6 -0.0 -0.6 -0.9 -1.1 -0.9 -0.2
Migraine (self-reported) 1.2 1.5 3.0 -0.5 -1.7 -1.0 -0.3 -1.3 1.4 1.4 0.6 1.7
Medication: Ibuprofen 0.5 0.6 2.1 0.9 0.7 0.9 0.3 1.4 0.7 -0.4 -0.2 -0.6
Medication: Allopurinol 0.5 0.7 2.2 0.2 0.4 0.1 -1.1 -1.3 1.5 0.8 -0.1 -0.2
Medication: Omeprazole 1.0 1.2 4.7 -0.1 -0.7 0.6 1.1 2.2 -1.0 -1.2 0.2 -1.2
Medication: Seretide 50 evohaler 0.8 0.9 4.1 0.5 0.3 0.6 0.4 1.6 0.7 -0.5 -0.1 -2.0
Mean time to correctly identify matches 0.2 0.3 0.7 0.1 -0.8 0.4 0.6 -0.6 0.3 -0.4 -0.5 -0.8
Heart disease (mother) 0.7 0.9 3.8 0.4 0.1 0.8 -0.3 0.9 -0.2 -1.2 -0.9 -2.0
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.8 1.0 2.9 1.5 0.5 0.6 -1.7 -0.6 1.2 0.4 -0.4 -1.0
Whole body fat mass 3.5 14.7 39.7 5.1 0.5 6.3 -0.8 -0.5 -1.9 -5.6 -3.9 -4.0
Leg fat mass (right) 3.7 14.3 38.6 5.1 0.4 6.2 -0.8 -0.6 -2.0 -5.6 -4.1 -3.3
Arm predicted mass (right) 2.0 10.5 27.7 4.2 -0.8 5.3 0.5 -0.3 -2.7 -5.2 -3.1 -2.1
Pulse rate, automated reading 0.2 0.5 1.2 -0.8 -1.0 -1.1 -0.9 -0.4 -0.7 0.5 0.1 -0.1
Alcohol intake frequency. 1.8 4.1 8.1 2.7 1.5 2.7 -1.6 -1.7 1.2 -1.6 -1.7 -2.8
Comparative height size at age 10 1.4 7.8 20.5 3.2 0.5 4.4 1.1 0.1 -1.6 -4.5 -2.6 -3.1
Number of full sisters 0.5 0.6 2.4 -0.4 0.9 -0.7 -0.8 0.3 -1.5 0.2 -0.1 0.9
Suffer from ‘nerves’ 1.5 2.3 9.0 -0.5 0.5 0.1 2.7 3.0 0.1 0.1 1.5 -1.4
Overall health rating 0.3 0.6 1.1 -0.5 -0.1 -1.0 1.1 0.9 0.3 1.0 0.9 0.6
Chest pain or discomfort 1.5 2.2 6.0 2.1 -0.9 1.9 -0.4 1.1 -0.6 -1.5 -1.0 -2.4
Had major operations 0.9 1.0 1.9 -0.7 -0.9 -1.1 1.0 0.5 0.6 1.4 1.3 1.1
Age at last live birth 0.2 0.2 0.7 -0.6 -0.4 -0.2 -0.1 -0.4 0.9 0.7 0.1 0.5
Family relationship satisfaction 1.6 1.9 4.2 -1.6 -1.0 -1.8 2.0 1.5 -0.4 0.9 1.5 0.9
Leg pain on walking 0.4 0.5 2.4 0.2 -1.6 -0.0 0.8 0.7 0.6 -0.1 0.3 -0.4
Qualifications: NVQ or HND or HNC or equivalent 0.2 0.2 0.8 -0.0 0.7 -0.2 -0.3 -0.1 -0.9 -0.5 -0.3 0.3
Commuting to job workplace: Car/motor vehicle 0.3 0.4 1.2 1.1 0.6 0.5 -0.3 -0.2 1.0 0.1 -0.1 -0.5
Illness, injury, bereavement, stress in last 2 years 0.4 0.5 1.5 0.2 -0.7 0.2 -1.2 -1.2 -0.5 -0.2 -0.5 0.6
Medication: Aspirin 1.3 1.7 7.0 -0.9 -2.7 -0.3 -1.2 -1.3 -1.4 -0.5 -0.7 1.2
Supplements: Vitamin C 0.7 0.9 2.7 -0.5 0.7 0.3 0.2 1.1 -1.6 -1.1 -0.6 -1.2
Knee pain experienced in last month 0.2 0.4 2.0 0.3 -1.4 -0.0 -0.1 1.0 -0.3 -0.1 -0.1 0.5
Hypertension (Self-reported) 4.5 12.6 25.0 -3.7 -2.5 -4.4 1.5 0.3 2.8 5.0 4.6 4.2
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.7 0.8 2.2 -1.0 0.2 -0.8 1.5 -0.3 -0.5 0.2 1.0 1.4
Illnesses of father: Heart disease 0.3 0.4 1.3 -0.8 -1.1 -0.2 0.4 0.0 -0.4 0.3 0.5 0.7
Illnesses of siblings: Diabetes 0.6 0.8 2.1 -0.3 -0.6 -0.3 0.4 0.9 1.1 0.9 1.2 -1.4
Smoking status: Previous 0.4 0.5 1.5 -1.0 0.3 -0.5 -0.2 -1.2 -0.4 0.5 0.3 1.2
Forced expiratory volume in 1-second (FEV1), predicted 1.6 3.4 6.8 1.5 0.7 2.6 1.6 2.6 -1.6 -2.3 -1.0 -1.7
Whole body fat-free mass 1.8 10.1 28.3 3.9 -0.4 5.3 0.5 -0.1 -2.6 -5.1 -3.1 -2.1
Leg fat-free mass (right) 1.7 9.2 26.2 3.9 -0.2 5.1 -0.3 -0.1 -2.5 -4.6 -3.1 -2.2
Arm fat percentage (left) 2.7 11.0 28.2 4.7 0.5 5.3 -1.6 -0.9 -1.1 -4.4 -3.5 -3.5
Average weekly red wine intake 0.0 0.1 0.2 0.1 -0.1 -0.2 -0.4 0.4 0.4 0.2 -0.1 -0.1
Handedness (chirality/laterality): Left-handed 0.8 1.0 3.4 -0.5 -1.8 -1.2 -0.4 -0.0 0.1 1.0 0.5 1.6
Mood swings 1.3 2.3 8.3 0.2 1.2 0.5 2.9 2.4 -0.1 -0.4 1.1 -1.9
Loneliness, isolation 3.4 4.6 12.2 -2.1 -0.6 -1.7 3.5 2.8 0.9 2.0 3.0 0.4
Long-standing illness, disability or infirmity 0.2 0.3 0.7 0.4 -0.5 0.3 -0.4 0.3 -0.6 -0.8 -0.6 -0.8
Ever had bowel cancer screening 1.0 1.2 2.4 1.1 -0.5 1.5 -0.1 -1.2 0.4 -1.3 -1.2 -1.5
Diabetes diagnosed by doctor 0.2 0.3 0.8 -0.5 -0.0 -0.8 0.1 -0.6 0.1 0.9 0.3 0.4
Ever had stillbirth, spontaneous miscarriage or termination 0.9 1.0 1.9 -0.2 -1.4 -0.8 0.8 1.0 1.2 1.0 1.3 -0.1
Friendships satisfaction 0.4 0.5 3.1 -0.0 -0.7 -0.7 0.2 -0.2 -0.3 0.1 0.0 1.8
Qualifications: nursing, teaching 0.1 0.2 0.7 0.3 0.3 0.8 -0.5 -0.2 -0.3 -0.4 -0.2 -0.4
Commuting to job workplace: Walk 0.5 0.5 2.3 -0.2 1.5 0.0 -0.1 0.4 -1.3 -0.4 -0.6 -0.2
Eye problems/disorders: Cataract 1.7 1.9 7.1 -2.7 -0.0 -1.6 1.1 1.3 -0.5 1.1 1.3 1.2
Mouth/teeth dental problems: Mouth ulcers 0.9 1.5 2.9 1.0 1.1 1.0 -1.5 -0.5 -1.6 -1.2 -1.7 -0.5
Medication for cholesterol 0.4 0.6 1.7 0.7 0.0 0.7 -0.4 0.2 -0.6 -1.2 -1.3 -1.0
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.5 0.5 1.3 -0.8 0.2 -1.1 1.1 0.9 -0.5 0.3 0.6 0.2
Back pain experienced in last month 0.8 1.2 2.5 1.6 -0.8 1.3 -0.4 -0.2 1.4 -1.1 -1.4 -0.9
Mineral and other dietary supplements 4.0 5.3 11.6 -2.3 -1.8 -2.4 1.0 0.5 1.9 3.4 3.0 2.9
Breast cancer (self-reported) 0.1 0.1 0.3 0.2 -0.3 0.3 0.2 -0.5 -0.3 -0.5 -0.2 -0.3
Asthma (self-reported) 0.7 1.3 2.7 -1.5 -0.2 -1.6 1.4 1.6 -0.4 0.9 0.9 0.9
Osteoporosis (self-reported) 0.4 0.4 1.1 -1.0 0.7 -1.0 -0.2 0.5 -0.2 1.0 0.3 0.1
Osteoarthritis (self-reported) 0.6 0.8 3.5 0.1 -0.9 -0.7 -1.2 -1.9 -0.6 -0.1 -0.7 0.5
Medication: Aspirin 1.3 1.7 6.6 -0.8 -2.6 -0.1 -1.2 -1.5 -1.2 -0.5 -0.7 1.3
Medication: Gliclazide 0.8 0.9 2.6 -0.8 0.4 -1.3 -0.1 0.5 -1.6 0.7 0.7 1.5
Illnesses of father: None of the above (group 1) 0.6 0.7 1.9 1.4 -0.6 1.1 -0.6 -0.2 0.8 -0.6 -0.8 -0.8
Smoking status: Current 0.7 1.2 2.6 -0.9 -1.1 -0.5 1.6 1.3 -0.2 0.2 1.5 -1.4
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.4 0.9 2.5 0.9 -0.3 1.6 0.9 0.6 -0.2 -1.4 -0.7 -1.1
Whole body water mass 1.8 10.3 28.2 3.9 -0.5 5.3 0.6 -0.0 -2.8 -5.2 -3.1 -2.2
Leg predicted mass (right) 1.7 9.3 26.3 3.9 -0.2 5.1 -0.3 -0.2 -2.5 -4.6 -3.1 -2.2
Arm fat mass (left) 3.4 14.1 36.8 5.1 0.4 6.1 -1.0 -0.6 -2.0 -5.5 -3.9 -3.7
Number of self-reported non-cancer illnesses 0.8 1.3 2.5 -1.1 -1.0 -1.1 1.5 1.2 0.9 1.1 1.6 0.4
Average weekly champagne plus white wine intake 2.6 3.6 8.0 -1.9 0.1 -2.8 1.7 2.0 -0.2 2.6 2.5 0.7
Miserableness 0.7 1.3 3.7 0.9 1.1 0.5 1.9 1.2 1.3 0.2 0.8 -1.3
Guilty feelings 3.4 5.1 12.7 -2.2 0.5 -2.2 3.6 2.7 1.7 2.4 2.7 0.7
Wears glasses or contact lenses 1.8 2.0 4.7 2.0 -0.7 1.8 -0.3 -0.3 -0.7 -1.9 -1.1 -2.2
Ever taken oral contraceptive pill 2.8 3.1 5.9 2.0 1.7 2.1 -1.8 -2.1 0.1 -1.7 -2.4 -0.4
Hearing aid user 0.3 0.3 1.5 -0.2 -0.0 -0.3 1.2 0.8 -0.3 0.0 0.5 -0.1
Mother’s age at death 2.9 3.6 6.9 2.1 -0.9 2.1 -1.4 -0.9 -1.8 -2.4 -2.1 -2.6
Financial situation satisfaction 1.4 1.8 5.2 -1.2 -1.4 -1.0 2.3 1.6 -0.2 0.9 1.5 0.6
Tinnitus: Yes, now most or all of the time 0.3 0.3 1.0 -0.6 -1.0 -0.3 -0.4 0.2 -0.9 -0.3 -0.6 0.3
Commuting to job workplace: Public transport 0.1 0.1 0.6 -0.5 0.4 -0.3 -0.1 0.1 -0.8 0.0 -0.1 0.2
Eye problems/disorders: Glaucoma 0.6 0.7 1.5 -0.3 -1.1 -0.7 -0.4 0.5 1.1 1.2 1.0 0.3
Medication: Blood pressure 4.1 7.7 16.9 -2.6 -0.7 -3.4 0.9 -0.2 2.0 4.0 3.5 4.1
Pain type(s) experienced in last month: Hip pain 0.7 0.9 2.4 0.9 -0.3 0.5 -0.7 -1.6 -0.3 -1.1 -1.4 0.5
Supplements: Fish oil (including cod liver oil) 2.4 3.2 9.3 0.5 0.6 1.1 -1.0 -0.8 -3.0 -2.9 -2.5 -1.1
High cholesterol (Self-reported) 0.5 0.9 2.6 1.5 -0.3 1.0 -0.2 -1.6 1.1 -0.5 -0.5 -0.5
Medication: Bendroflumethiazide 1.7 2.6 7.0 -1.6 -1.5 -1.4 0.2 0.3 0.5 2.0 2.3 2.6
Medication: Paracetamol 0.6 0.9 2.2 -0.7 0.1 -1.0 0.1 0.2 1.3 1.5 0.9 1.3
Medication: Lisinopril 0.4 0.6 2.7 -0.5 -1.6 0.1 0.2 0.9 -0.3 0.4 1.0 -0.2
Medication: Atorvastatin 1.0 1.3 4.1 0.7 -1.1 1.2 0.8 0.1 2.0 0.3 0.6 -1.7
Illnesses of father: High blood pressure 2.0 2.5 9.3 -2.2 0.6 -2.0 0.6 0.5 -1.2 1.1 0.9 3.0
Alcohol drinker status: Never 0.4 0.4 0.8 0.8 0.2 0.7 -0.6 -0.9 0.3 -0.7 -0.7 -0.8
Ever smoked 0.2 0.3 1.3 -0.7 0.1 -0.4 0.7 -0.1 -1.1 -0.4 0.0 0.2
Basal metabolic rate 2.2 12.4 34.2 4.4 -0.2 5.8 0.2 -0.1 -2.9 -5.6 -3.5 -2.5
Leg fat percentage (left) 2.2 7.8 20.6 4.0 0.4 4.5 -0.6 -0.5 -1.3 -3.9 -2.9 -2.7
Arm fat-free mass (left) 2.5 12.4 33.0 4.4 -0.5 5.7 0.3 -0.2 -2.9 -5.6 -3.6 -2.5
Number of operations (self-reported) 1.2 1.8 4.3 -0.8 -0.8 -1.7 0.6 0.3 1.4 2.1 1.7 1.6
Average weekly beer plus cider intake 0.8 1.2 3.7 -0.9 -0.5 0.0 1.9 1.4 -1.5 -1.1 0.0 0.8
Irritability 1.7 2.9 8.5 -1.4 0.0 -1.3 2.9 1.4 1.8 1.8 2.3 0.1
Risk taking 2.7 4.0 12.1 -2.0 1.1 -1.0 3.4 3.5 -1.5 0.2 1.8 -1.1
Ever had prostate specific antigen (PSA) test 1.1 1.3 3.2 -0.4 0.9 -0.1 1.8 1.8 1.2 0.7 1.1 -1.2
Fractured/broken bones in last 5 years 0.8 1.0 2.9 -0.6 -0.9 -1.2 -0.5 0.5 1.3 1.7 1.0 -0.5
Age started oral contraceptive pill 2.0 2.5 7.0 1.8 0.0 2.1 -0.3 -0.3 -1.0 -2.7 -2.0 -1.7
Diastolic blood pressure, automated reading 4.4 13.6 30.1 -3.9 -1.1 -5.5 0.7 0.6 1.6 5.4 4.1 5.1
Ever depressed for a whole week 1.0 1.2 4.3 -0.6 -0.6 -0.2 1.7 2.1 -1.6 -0.5 0.5 -0.3
Unable to work because of sickness or disability 0.5 0.7 2.4 0.9 -0.8 0.9 0.2 0.3 1.1 -0.2 -0.1 -1.6
Commuting to job workplace: Cycle 2.7 3.3 9.5 1.2 -1.4 2.0 -0.5 -0.7 -2.3 -3.1 -2.5 -0.4
Myopia 0.8 1.1 2.0 1.3 -0.9 1.4 -0.6 -0.6 0.2 -1.3 -1.3 -1.1
Vascular/heart problems diagnosed by doctor 3.5 9.4 19.4 2.5 2.6 3.5 -0.7 1.0 -3.3 -4.4 -3.6 -3.8
Cholesterol lowering medication 0.9 1.3 3.1 1.7 0.8 1.8 1.1 -0.2 0.3 -1.0 -0.4 -1.7
Medication: Omeprazole (e.g. Zanprol) 0.4 0.5 2.0 -0.0 -0.9 0.0 1.0 1.4 -0.4 -0.7 0.4 -0.5
Pain experienced in last month 0.5 0.8 1.8 -0.6 1.1 0.2 -1.3 -1.3 -1.2 -0.5 -0.5 0.5
Supplements: Calcium 1.9 2.1 5.6 1.1 1.5 1.6 0.8 1.3 -0.4 -1.8 -1.4 -2.4
Basal cell carcinoma (self-reported) 0.5 0.6 2.0 -0.2 -0.9 0.2 1.1 0.8 1.4 0.1 0.4 0.2
Heart attack/myocardial infarction (self-reported) 1.5 1.9 12.0 0.5 0.1 -0.2 -1.0 -1.3 3.5 1.2 0.1 0.8
Deep venous thrombosis (DVT) (self-reported) 0.8 1.0 2.6 1.3 -1.2 1.6 -0.1 -0.6 0.5 -0.9 -0.6 -1.4
Heart disease (siblings) 1.0 1.2 2.6 0.5 0.7 1.5 0.6 1.6 -0.5 -1.4 -0.7 -1.4
Alcohol drinker status: Previous 2.4 2.8 5.9 -1.9 0.4 -1.4 1.4 0.9 2.4 2.3 2.3 0.3
Pack years of smoking 2.6 3.8 8.3 -2.2 0.8 -2.9 0.7 1.1 0.8 2.7 2.4 2.2
Impedance of whole body 0.8 4.1 7.4 -2.3 1.4 -2.0 2.2 2.0 2.0 2.3 2.7 -0.6
Leg fat mass (left) 3.6 13.9 37.7 5.1 0.3 6.1 -0.9 -0.6 -1.9 -5.4 -4.0 -3.3
Arm predicted mass (left) 2.2 11.2 29.5 4.2 -0.3 5.4 0.3 -0.1 -3.0 -5.3 -3.4 -2.3