[Hub]/) : Traits : Waist circumference : ← →

chr11:29,646,947-31,288,160

Best TWAS P=2.09e-12 · Best GWAS P=2.07e-11 conditioned to 1.78e-05

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Artery Aorta ARL14EP 0.16 0.02 lasso 5 0.05 7.4e-04 -6.5 -5.2 2.2e-07 0.47 0.08 0.85 FALSE
2 GTEx Brain Cerebellum ARL14EP 0.33 0.25 lasso 10 0.26 3.7e-08 6.5 -6.8 1.1e-11 0.40 0.02 0.98 FALSE
3 GTEx Colon Sigmoid ARL14EP 0.16 0.05 lasso 13 0.10 2.6e-04 6.3 -5.5 5.0e-08 0.51 0.06 0.72 FALSE
4 GTEx Esophagus Gastroesophageal Junction ARL14EP 0.15 0.14 lasso 3 0.11 1.2e-04 6.5 -6.6 5.3e-11 0.39 0.02 0.96 FALSE
5 GTEx Esophagus Mucosa ARL14EP 0.09 0.03 enet 11 0.05 1.8e-04 6.3 -5.3 9.5e-08 0.49 0.06 0.86 FALSE
6 GTEx Esophagus Muscularis ARL14EP 0.18 0.20 lasso 8 0.19 9.5e-12 6.6 -7.0 3.2e-12 0.46 0.02 0.98 FALSE
7 GTEx Lung ARL14EP 0.10 0.06 lasso 8 0.11 1.1e-08 -2.6 -5.7 9.5e-09 0.71 0.44 0.56 FALSE
8 GTEx Nerve Tibial ARL14EP 0.19 0.17 enet 22 0.18 4.2e-13 6.5 -6.1 1.2e-09 0.46 0.02 0.98 FALSE
9 GTEx Pancreas ARL14EP 0.16 0.08 lasso 6 0.07 1.0e-03 6.2 -7.0 2.1e-12 0.39 0.02 0.93 TRUE
10 GTEx Pituitary ARL14EP 0.30 0.28 lasso 4 0.22 3.0e-06 6.6 -6.9 4.2e-12 0.55 0.02 0.95 FALSE
11 ROSMAP Brain Pre-frontal Cortex MPPED2 0.25 0.29 lasso 7 0.29 4.4e-37 5.7 -5.9 3.9e-09 0.54 0.10 0.90 FALSE
12 ROSMAP Brain Pre-frontal Cortex ARL14EP 0.08 0.07 enet 13 0.08 5.3e-10 6.6 -6.0 1.8e-09 0.35 0.02 0.98 FALSE
13 The Cancer Genome Atlas Lung Adenocarcinoma MPPED2 0.07 0.01 blup 149 0.03 7.0e-05 6.6 -5.6 2.1e-08 0.38 0.02 0.95 FALSE