Best TWAS P=9.37e-08 · Best GWAS P=3.06e-08 conditioned to 0.0195
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | ANKK1 | 0.04 | 0.02 | blup | 66 | 0.03 | 0.0005 | 4.4 | 5.3 | 9.4e-08 | 0.75 | 0.03 | 0.86 | TRUE |
2 | The Cancer Genome Atlas | Liver Hepatocellular Carcinoma | ANKK1 | 0.08 | 0.02 | blup | 66 | 0.04 | 0.0056 | 4.5 | -5.2 | 1.7e-07 | -0.75 | 0.01 | 0.89 | FALSE |
3 | The Cancer Genome Atlas | Testicular Germ Cell Tumors | TTC12 | 0.07 | 0.06 | blup | 48 | 0.04 | 0.0163 | 5.3 | 5.3 | 1.1e-07 | 0.66 | 0.00 | 0.86 | FALSE |