Best TWAS P=3.14e-08 · Best GWAS P=1.25e-06 conditioned to 0.232
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | NLRX1 | 0.04 | 0.03 | enet | 14 | 0.02 | 1.2e-03 | -4.5 | -5.4 | 5.1e-08 | 0.92 | 0.01 | 0.92 | FALSE |
| 2 | The Cancer Genome Atlas | Bladder Urothelial Carcinoma | CBL | 0.07 | 0.05 | enet | 6 | 0.06 | 5.8e-06 | -4.8 | 5.5 | 4.8e-08 | -0.92 | 0.00 | 0.98 | FALSE |
| 3 | The Cancer Genome Atlas | Bladder Urothelial Carcinoma | HMBS | 0.08 | 0.03 | blup | 38 | 0.04 | 1.7e-04 | 3.8 | 5.3 | 1.0e-07 | -0.30 | 0.00 | 0.10 | FALSE |
| 4 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | NLRX1 | 0.05 | 0.03 | enet | 5 | 0.05 | 2.4e-06 | 4.2 | -5.5 | 3.1e-08 | 0.73 | 0.03 | 0.72 | TRUE |