Best TWAS P=1.63e-08 · Best GWAS P=4.18e-09 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adrenal Gland | ZNF605 | 0.23 | 0.07 | lasso | 9 | 0.06 | 4.5e-03 | 5.8 | 5.6 | 1.6e-08 | 0.95 | 0.01 | 0.96 | TRUE |
| 2 | GTEx | Breast Mammary Tissue (Female) | ANKLE2 | 0.11 | 0.01 | enet | 17 | 0.06 | 7.4e-03 | 4.7 | 5.4 | 8.3e-08 | 0.67 | 0.02 | 0.51 | FALSE |
| 3 | GTEx | Muscle Skeletal | ANKLE2 | 0.06 | 0.01 | enet | 17 | 0.03 | 8.8e-04 | 5.8 | 5.2 | 2.0e-07 | 0.74 | 0.00 | 0.96 | FALSE |
| 4 | The Cancer Genome Atlas | Breast Invasive Carcinoma | ANKLE2 | 0.04 | 0.02 | lasso | 2 | 0.02 | 5.8e-06 | 5.7 | 5.6 | 2.6e-08 | 0.96 | 0.00 | 1.00 | FALSE |