[Hub]/) : Traits : Hip circumference : ← →

chr12:121,194,565-125,750,969

Best TWAS P=2.46e-33 · Best GWAS P=5.19e-32 conditioned to NaN

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
8	GTEx	Adipose Visceral Omentum	CCDC92	0.19	0.02	lasso	8	0.09	3.3e-05	7.7	12.0	2.5e-33	-0.12	0.03	0.96	TRUE
85	The Cancer Genome Atlas	Stomach Adenocarcinoma	MLXIP	0.06	0.02	blup	68	0.04	1.2e-03	9.7	11.2	4.0e-29	-0.23	0.02	0.89	TRUE
27	GTEx	Colon Transverse	MLXIP	0.20	0.18	enet	23	0.14	5.8e-07	9.9	9.3	1.2e-20	-0.17	1.00	0.00	TRUE
54	GTEx	Testis	ABCB9	0.14	0.05	lasso	3	0.06	8.0e-04	7.7	-8.6	6.3e-18	0.22	0.25	0.05	TRUE
39	GTEx	Muscle Skeletal	RSRC2	0.06	0.03	enet	7	0.04	9.6e-05	-5.0	-8.1	6.5e-16	0.43	0.25	0.48	TRUE
31	GTEx	Esophagus Mucosa	HIP1R	0.21	0.05	lasso	5	0.07	1.5e-05	5.0	7.8	5.6e-15	-0.21	0.47	0.26	TRUE
23	GTEx	Cells Transformed fibroblasts	BCL7A	0.06	0.01	lasso	4	0.01	3.1e-02	3.1	-7.2	7.6e-13	0.24	0.09	0.05	TRUE
29	GTEx	Esophagus Mucosa	KDM2B	0.11	0.04	enet	22	0.10	4.1e-07	2.5	6.0	1.7e-09	-0.10	0.92	0.01	TRUE
57	GTEx	Thyroid	WDR66	0.11	0.02	lasso	6	0.02	1.1e-02	-4.1	5.5	3.3e-08	-0.01	0.13	0.13	TRUE
62	METSIM	Adipose	CLIP1	0.03	0.01	bslmm	372	0.01	3.3e-03	-6.1	5.5	3.9e-08	-0.31	0.60	0.04	TRUE
52	GTEx	Stomach	AC084018.1	0.13	0.13	enet	23	0.13	8.7e-07	3.7	-5.4	7.9e-08	-0.01	0.79	0.02	TRUE
70	YFS	Blood	RILPL2	0.37	0.15	enet	28	0.17	1.3e-53	-6.3	-5.2	2.2e-07	0.09	1.00	0.00	TRUE
68	YFS	Blood	NCOR2	0.06	0.00	blup	591	0.02	3.7e-08	-1.1	5.2	2.4e-07	0.03	0.34	0.04	TRUE
10	GTEx	Adipose Visceral Omentum	RP11-380L11.3	0.15	0.03	lasso	5	0.01	1.4e-01	8.6	11.8	3.2e-32	-0.08	0.01	0.91	FALSE
5	GTEx	Adipose Subcutaneous	RP11-380L11.3	0.09	0.03	lasso	3	0.03	1.4e-03	7.6	10.7	7.7e-27	-0.07	0.10	0.87	FALSE
61	METSIM	Adipose	CCDC92	0.10	0.01	bslmm	435	0.06	5.5e-10	-4.8	10.3	6.8e-25	-0.08	0.01	0.99	FALSE
4	GTEx	Adipose Subcutaneous	CCDC92	0.23	0.04	enet	27	0.16	6.9e-13	-7.6	10.3	1.2e-24	-0.09	0.02	0.98	FALSE
37	GTEx	Lung	CCDC92	0.14	0.00	enet	10	0.01	1.1e-01	9.5	9.9	6.1e-23	-0.08	0.00	0.98	FALSE
75	The Cancer Genome Atlas	Colon Adenocarcinoma	MLXIP	0.06	0.04	lasso	7	0.02	2.7e-02	9.7	9.6	6.8e-22	-0.17	0.02	0.94	FALSE
43	GTEx	Nerve Tibial	CCDC92	0.16	0.01	enet	6	0.04	6.7e-04	6.4	9.3	1.6e-20	-0.10	0.12	0.41	FALSE
84	The Cancer Genome Atlas	Rectum Adenocarcinoma	MLXIP	0.18	0.14	lasso	4	0.13	5.1e-04	8.8	9.2	2.4e-20	-0.16	0.02	0.89	FALSE
56	GTEx	Thyroid	CCDC92	0.06	0.03	lasso	3	0.02	1.1e-02	7.6	9.2	3.6e-20	-0.08	0.53	0.05	FALSE
66	METSIM	Adipose	RP11-214K3.24	0.05	0.03	bslmm	444	0.02	2.7e-04	6.6	8.9	3.7e-19	-0.07	0.57	0.05	FALSE
34	GTEx	Heart Atrial Appendage	RP11-380L11.4	0.18	0.11	lasso	7	0.12	6.5e-06	7.7	8.6	1.1e-17	-0.07	0.82	0.01	FALSE
35	GTEx	Heart Left Ventricle	CCDC92	0.26	0.19	lasso	4	0.21	1.9e-11	6.6	8.5	1.5e-17	-0.06	1.00	0.00	FALSE
22	GTEx	Breast Mammary Tissue (Female)	C12orf65	0.06	0.00	enet	13	-0.01	6.5e-01	-5.9	-8.3	1.1e-16	0.27	0.05	0.08	FALSE
72	The Cancer Genome Atlas	Breast Invasive Carcinoma	DNAH10	0.11	0.03	blup	99	0.05	8.2e-11	6.6	7.9	2.1e-15	-0.05	0.12	0.88	FALSE
89	The Cancer Genome Atlas	Thyroid Carcinoma	ZNF664	0.06	0.05	enet	9	0.05	2.8e-05	7.6	-7.9	2.2e-15	0.08	0.94	0.00	FALSE
26	GTEx	Colon Sigmoid	RP11-380L11.4	0.21	0.12	lasso	3	0.08	1.1e-03	7.6	7.9	2.3e-15	-0.06	0.36	0.08	FALSE
3	GTEx	Adipose Subcutaneous	ZCCHC8	0.04	0.00	lasso	7	0.00	1.4e-01	5.0	7.8	5.3e-15	-0.31	0.17	0.10	FALSE
28	GTEx	Colon Transverse	SNRNP35	0.18	0.02	lasso	8	0.04	6.5e-03	-4.9	7.8	8.8e-15	-0.16	0.06	0.24	FALSE
77	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	DNAH10	0.07	0.03	lasso	3	0.05	7.4e-06	7.7	7.7	1.9e-14	-0.06	0.04	0.95	FALSE
32	GTEx	Esophagus Muscularis	RP11-380L11.4	0.27	0.29	lasso	8	0.27	1.0e-16	7.6	7.6	3.1e-14	-0.05	1.00	0.00	FALSE
38	GTEx	Lung	RP11-380L11.4	0.07	0.07	lasso	3	0.07	8.2e-06	7.8	7.6	3.2e-14	-0.06	0.94	0.00	FALSE
58	GTEx	Thyroid	ZNF664	0.13	0.06	lasso	11	0.08	6.7e-07	6.3	-7.5	9.2e-14	0.04	1.00	0.00	FALSE
15	GTEx	Artery Tibial	RP11-380L11.4	0.14	0.12	lasso	4	0.12	2.2e-09	7.6	7.4	1.1e-13	-0.04	1.00	0.00	FALSE
20	GTEx	Breast Mammary Tissue (Male)	CCDC92	0.06	-0.01	lasso	3	0.00	4.3e-01	6.4	7.3	2.2e-13	-0.07	0.04	0.07	FALSE
86	The Cancer Genome Atlas	Thyroid Carcinoma	DNAH10	0.04	0.03	lasso	5	0.02	4.6e-03	6.4	7.3	3.7e-13	-0.05	0.02	0.83	FALSE
88	The Cancer Genome Atlas	Thyroid Carcinoma	VPS33A	0.06	0.00	enet	8	0.03	9.6e-04	5.0	-7.2	6.3e-13	0.20	0.06	0.94	FALSE
33	GTEx	Heart Atrial Appendage	CCDC92	0.12	0.11	enet	9	0.11	1.1e-05	5.2	7.1	1.6e-12	-0.05	0.66	0.08	FALSE
1	CommonMind	Brain Pre-frontal Cortex	CCDC62	0.12	0.06	enet	21	0.06	3.3e-08	4.8	-7.0	2.1e-12	0.13	0.99	0.00	FALSE
76	The Cancer Genome Atlas	Glioblastoma Multiforme	CCDC92	0.07	0.02	blup	52	0.04	1.8e-02	6.3	7.0	3.6e-12	-0.05	0.08	0.05	FALSE
18	GTEx	Brain Putamen basal ganglia	WDR66	0.25	0.01	enet	16	-0.01	5.6e-01	8.6	-6.9	5.0e-12	0.15	0.06	0.30	FALSE
30	GTEx	Esophagus Mucosa	CCDC92	0.11	0.02	lasso	4	0.02	1.9e-02	6.6	6.8	8.0e-12	-0.05	0.44	0.04	FALSE
11	GTEx	Artery Aorta	C12orf65	0.11	0.07	lasso	10	0.08	5.8e-05	5.1	-6.8	1.2e-11	0.21	0.77	0.02	FALSE
60	METSIM	Adipose	ABCB9	0.04	0.03	enet	19	0.03	7.7e-05	-5.4	-6.8	1.5e-11	0.38	0.08	0.65	FALSE
44	GTEx	Nerve Tibial	KNTC1	0.12	0.05	lasso	5	0.05	1.9e-04	-5.7	-6.7	2.7e-11	0.31	0.53	0.03	FALSE
71	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	LRRC43	0.06	0.03	enet	6	0.03	8.7e-04	-5.5	-6.7	2.9e-11	0.10	0.13	0.22	FALSE
78	The Cancer Genome Atlas	Brain Lower Grade Glioma	LRRC43	0.03	0.03	enet	8	0.02	1.5e-03	-5.3	-6.6	3.3e-11	0.15	0.10	0.06	FALSE
63	METSIM	Adipose	DNAH10	0.03	0.00	bslmm	475	0.01	3.2e-03	8.2	6.5	6.7e-11	-0.01	0.04	0.81	FALSE
51	GTEx	Skin Sun Exposed Lower leg	RP11-380L11.4	0.04	0.02	enet	15	0.02	1.9e-02	7.7	6.5	9.5e-11	-0.04	0.41	0.03	FALSE
46	GTEx	Prostate	CCDC92	0.31	0.10	enet	42	0.11	9.0e-04	6.3	6.4	1.2e-10	-0.08	0.21	0.05	FALSE
67	METSIM	Adipose	TCTN2	0.22	0.11	blup	395	0.12	2.0e-17	-3.0	-6.4	1.2e-10	0.10	1.00	0.00	FALSE
65	METSIM	Adipose	MLXIP	0.08	0.07	enet	25	0.07	2.3e-10	-7.0	6.4	1.3e-10	-0.07	1.00	0.00	FALSE
59	GTEx	Whole Blood	DDX55	0.13	0.04	enet	13	0.06	3.3e-06	-4.4	6.3	2.5e-10	-0.17	0.34	0.02	FALSE
82	The Cancer Genome Atlas	Prostate Adenocarcinoma	LRRC43	0.04	0.00	blup	58	0.01	6.9e-02	8.6	-6.3	2.6e-10	0.12	0.02	0.19	FALSE
21	GTEx	Breast Mammary Tissue (Female)	CCDC92	0.05	-0.01	enet	2	-0.01	6.2e-01	6.3	6.3	3.5e-10	-0.04	0.04	0.17	FALSE
14	GTEx	Artery Tibial	RP11-282O18.3	0.17	0.08	enet	26	0.10	2.4e-08	5.1	-6.0	1.9e-09	0.10	0.99	0.00	FALSE
55	GTEx	Testis	RP11-282O18.3	0.18	0.09	lasso	9	0.12	7.8e-06	4.4	-6.0	1.9e-09	0.14	0.36	0.04	FALSE
80	The Cancer Genome Atlas	Prostate Adenocarcinoma	GPR109A	0.03	0.01	blup	21	0.01	1.3e-02	-3.8	-6.0	2.4e-09	0.29	0.05	0.03	FALSE
40	GTEx	Muscle Skeletal	SETD8	0.16	0.02	lasso	4	0.03	3.8e-04	4.5	6.0	2.6e-09	-0.13	0.81	0.02	FALSE
2	CommonMind	Brain Pre-frontal Cortex	HIP1R	0.06	0.02	lasso	6	0.04	1.9e-05	-5.4	-5.9	2.7e-09	0.09	0.18	0.02	FALSE
48	GTEx	Skin Sun Exposed Lower leg	DDX55	0.13	0.05	enet	13	0.10	1.6e-08	-4.5	5.9	2.9e-09	-0.13	1.00	0.00	FALSE
6	GTEx	Adipose Visceral Omentum	MPHOSPH9	0.07	0.02	lasso	4	0.00	3.5e-01	4.6	5.8	8.4e-09	-0.13	0.14	0.08	FALSE
74	The Cancer Genome Atlas	Breast Invasive Carcinoma	VPS33A	0.01	0.02	lasso	2	0.02	2.7e-04	5.7	-5.7	9.0e-09	0.14	0.33	0.24	FALSE
7	GTEx	Adipose Visceral Omentum	CDK2AP1	0.14	0.14	lasso	4	0.11	2.7e-06	4.6	-5.7	1.2e-08	0.12	0.99	0.00	FALSE
9	GTEx	Adipose Visceral Omentum	RP11-282O18.3	0.14	0.11	enet	12	0.10	6.7e-06	4.6	-5.7	1.2e-08	0.12	0.98	0.00	FALSE
16	GTEx	Brain Cerebellar Hemisphere	WDR66	0.28	0.05	lasso	8	0.04	3.6e-02	-3.8	-5.7	1.3e-08	0.10	0.09	0.07	FALSE
45	GTEx	Pancreas	RP11-347I19.8	0.12	0.00	enet	13	0.00	2.9e-01	3.8	-5.6	1.6e-08	0.00	0.10	0.05	FALSE
83	The Cancer Genome Atlas	Prostate Adenocarcinoma	VPS33A	0.04	0.05	lasso	1	0.04	3.0e-05	5.7	-5.7	1.6e-08	0.13	0.88	0.11	FALSE
87	The Cancer Genome Atlas	Thyroid Carcinoma	PSMD9	0.09	0.10	lasso	4	0.10	7.4e-10	-5.7	5.7	1.6e-08	-0.02	0.01	0.99	FALSE
13	GTEx	Artery Tibial	CCDC92	0.19	0.06	enet	40	0.06	1.5e-05	8.0	5.6	2.6e-08	-0.06	0.33	0.05	FALSE
41	GTEx	Muscle Skeletal	RP11-380L11.4	0.14	0.03	lasso	8	0.03	4.0e-04	7.6	5.6	2.6e-08	-0.04	0.88	0.00	FALSE
12	GTEx	Artery Tibial	CDK2AP1	0.17	0.07	enet	36	0.09	1.1e-07	5.1	-5.5	3.4e-08	0.09	0.99	0.00	FALSE
24	GTEx	Cells Transformed fibroblasts	CCDC92	0.09	0.00	enet	28	0.01	3.8e-02	7.5	5.5	3.6e-08	-0.12	0.07	0.24	FALSE
36	GTEx	Lung	CDK2AP1	0.08	0.03	lasso	4	0.00	2.0e-01	4.3	-5.5	3.8e-08	0.12	0.58	0.05	FALSE
53	GTEx	Stomach	RP11-347I19.8	0.22	0.09	lasso	7	0.11	4.2e-06	3.7	-5.5	4.6e-08	-0.02	0.95	0.01	FALSE
17	GTEx	Brain Hippocampus	CLIP1	0.27	0.14	lasso	4	0.12	1.0e-03	-2.8	-5.5	4.7e-08	0.24	0.05	0.48	FALSE
42	GTEx	Muscle Skeletal	RP11-347I19.8	0.08	0.06	lasso	4	0.06	2.4e-06	3.3	-5.5	5.0e-08	0.03	0.96	0.00	FALSE
79	The Cancer Genome Atlas	Brain Lower Grade Glioma	VPS33A	0.03	0.05	lasso	1	0.05	4.4e-06	5.4	-5.4	5.7e-08	0.13	0.93	0.03	FALSE
81	The Cancer Genome Atlas	Prostate Adenocarcinoma	GPR81	0.07	0.02	blup	54	0.02	4.4e-03	5.7	5.4	7.4e-08	-0.13	0.04	0.20	FALSE
25	GTEx	Cells Transformed fibroblasts	C12orf65	0.07	0.05	lasso	4	0.04	5.8e-04	5.2	-5.4	8.7e-08	0.14	0.32	0.49	FALSE
73	The Cancer Genome Atlas	Breast Invasive Carcinoma	LRRC43	0.04	0.04	lasso	2	0.04	3.0e-08	-5.3	-5.3	9.4e-08	0.09	1.00	0.00	FALSE
64	METSIM	Adipose	LRRC43	0.05	0.05	lasso	2	0.04	7.3e-07	-5.3	-5.3	9.7e-08	0.09	0.96	0.00	FALSE
50	GTEx	Skin Sun Exposed Lower leg	WDR66	0.19	0.10	lasso	5	0.08	5.5e-07	3.1	5.3	1.0e-07	-0.11	0.98	0.00	FALSE
47	GTEx	Skin Not Sun Exposed Suprapubic	KNTC1	0.11	0.04	lasso	4	0.03	7.1e-03	5.5	-5.3	1.2e-07	0.14	0.22	0.04	FALSE
49	GTEx	Skin Sun Exposed Lower leg	CCDC92	0.11	0.00	enet	15	0.01	1.0e-01	7.5	5.2	1.7e-07	-0.12	0.08	0.38	FALSE
19	GTEx	Breast Mammary Tissue	ATP6V0A2	0.09	0.02	lasso	4	0.03	9.7e-03	-3.0	-5.2	1.8e-07	0.15	0.37	0.04	FALSE
69	YFS	Blood	PSMD9	0.04	0.03	bslmm	324	0.05	8.2e-15	-5.7	5.2	2.0e-07	-0.08	1.00	0.00	FALSE