[Hub]/) : Traits : Hip circumference :

chr12:121,194,565-125,750,969

Best TWAS P=2.46e-33 · Best GWAS P=5.19e-32 conditioned to NaN

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex CCDC62 0.12 0.06 enet 21 0.06 3.3e-08 4.8 -7.0 2.1e-12 0.13 0.99 0.00 FALSE
2 CommonMind Brain Pre-frontal Cortex HIP1R 0.06 0.02 lasso 6 0.04 1.9e-05 -5.4 -5.9 2.7e-09 0.09 0.18 0.02 FALSE
3 GTEx Adipose Subcutaneous ZCCHC8 0.04 0.00 lasso 7 0.00 1.4e-01 5.0 7.8 5.3e-15 -0.31 0.17 0.10 FALSE
4 GTEx Adipose Subcutaneous CCDC92 0.23 0.04 enet 27 0.16 6.9e-13 -7.6 10.3 1.2e-24 -0.09 0.02 0.98 FALSE
5 GTEx Adipose Subcutaneous RP11-380L11.3 0.09 0.03 lasso 3 0.03 1.4e-03 7.6 10.7 7.7e-27 -0.07 0.10 0.87 FALSE
6 GTEx Adipose Visceral Omentum MPHOSPH9 0.07 0.02 lasso 4 0.00 3.5e-01 4.6 5.8 8.4e-09 -0.13 0.14 0.08 FALSE
7 GTEx Adipose Visceral Omentum CDK2AP1 0.14 0.14 lasso 4 0.11 2.7e-06 4.6 -5.7 1.2e-08 0.12 0.99 0.00 FALSE
8 GTEx Adipose Visceral Omentum CCDC92 0.19 0.02 lasso 8 0.09 3.3e-05 7.7 12.0 2.5e-33 -0.12 0.03 0.96 TRUE
9 GTEx Adipose Visceral Omentum RP11-282O18.3 0.14 0.11 enet 12 0.10 6.7e-06 4.6 -5.7 1.2e-08 0.12 0.98 0.00 FALSE
10 GTEx Adipose Visceral Omentum RP11-380L11.3 0.15 0.03 lasso 5 0.01 1.4e-01 8.6 11.8 3.2e-32 -0.08 0.01 0.91 FALSE
11 GTEx Artery Aorta C12orf65 0.11 0.07 lasso 10 0.08 5.8e-05 5.1 -6.8 1.2e-11 0.21 0.77 0.02 FALSE
12 GTEx Artery Tibial CDK2AP1 0.17 0.07 enet 36 0.09 1.1e-07 5.1 -5.5 3.4e-08 0.09 0.99 0.00 FALSE
13 GTEx Artery Tibial CCDC92 0.19 0.06 enet 40 0.06 1.5e-05 8.0 5.6 2.6e-08 -0.06 0.33 0.05 FALSE
14 GTEx Artery Tibial RP11-282O18.3 0.17 0.08 enet 26 0.10 2.4e-08 5.1 -6.0 1.9e-09 0.10 0.99 0.00 FALSE
15 GTEx Artery Tibial RP11-380L11.4 0.14 0.12 lasso 4 0.12 2.2e-09 7.6 7.4 1.1e-13 -0.04 1.00 0.00 FALSE
16 GTEx Brain Cerebellar Hemisphere WDR66 0.28 0.05 lasso 8 0.04 3.6e-02 -3.8 -5.7 1.3e-08 0.10 0.09 0.07 FALSE
17 GTEx Brain Hippocampus CLIP1 0.27 0.14 lasso 4 0.12 1.0e-03 -2.8 -5.5 4.7e-08 0.24 0.05 0.48 FALSE
18 GTEx Brain Putamen basal ganglia WDR66 0.25 0.01 enet 16 -0.01 5.6e-01 8.6 -6.9 5.0e-12 0.15 0.06 0.30 FALSE
19 GTEx Breast Mammary Tissue ATP6V0A2 0.09 0.02 lasso 4 0.03 9.7e-03 -3.0 -5.2 1.8e-07 0.15 0.37 0.04 FALSE
20 GTEx Breast Mammary Tissue (Male) CCDC92 0.06 -0.01 lasso 3 0.00 4.3e-01 6.4 7.3 2.2e-13 -0.07 0.04 0.07 FALSE
21 GTEx Breast Mammary Tissue (Female) CCDC92 0.05 -0.01 enet 2 -0.01 6.2e-01 6.3 6.3 3.5e-10 -0.04 0.04 0.17 FALSE
22 GTEx Breast Mammary Tissue (Female) C12orf65 0.06 0.00 enet 13 -0.01 6.5e-01 -5.9 -8.3 1.1e-16 0.27 0.05 0.08 FALSE
23 GTEx Cells Transformed fibroblasts BCL7A 0.06 0.01 lasso 4 0.01 3.1e-02 3.1 -7.2 7.6e-13 0.24 0.09 0.05 TRUE
24 GTEx Cells Transformed fibroblasts CCDC92 0.09 0.00 enet 28 0.01 3.8e-02 7.5 5.5 3.6e-08 -0.12 0.07 0.24 FALSE
25 GTEx Cells Transformed fibroblasts C12orf65 0.07 0.05 lasso 4 0.04 5.8e-04 5.2 -5.4 8.7e-08 0.14 0.32 0.49 FALSE
26 GTEx Colon Sigmoid RP11-380L11.4 0.21 0.12 lasso 3 0.08 1.1e-03 7.6 7.9 2.3e-15 -0.06 0.36 0.08 FALSE
27 GTEx Colon Transverse MLXIP 0.20 0.18 enet 23 0.14 5.8e-07 9.9 9.3 1.2e-20 -0.17 1.00 0.00 TRUE
28 GTEx Colon Transverse SNRNP35 0.18 0.02 lasso 8 0.04 6.5e-03 -4.9 7.8 8.8e-15 -0.16 0.06 0.24 FALSE
29 GTEx Esophagus Mucosa KDM2B 0.11 0.04 enet 22 0.10 4.1e-07 2.5 6.0 1.7e-09 -0.10 0.92 0.01 TRUE
30 GTEx Esophagus Mucosa CCDC92 0.11 0.02 lasso 4 0.02 1.9e-02 6.6 6.8 8.0e-12 -0.05 0.44 0.04 FALSE
31 GTEx Esophagus Mucosa HIP1R 0.21 0.05 lasso 5 0.07 1.5e-05 5.0 7.8 5.6e-15 -0.21 0.47 0.26 TRUE
32 GTEx Esophagus Muscularis RP11-380L11.4 0.27 0.29 lasso 8 0.27 1.0e-16 7.6 7.6 3.1e-14 -0.05 1.00 0.00 FALSE
33 GTEx Heart Atrial Appendage CCDC92 0.12 0.11 enet 9 0.11 1.1e-05 5.2 7.1 1.6e-12 -0.05 0.66 0.08 FALSE
34 GTEx Heart Atrial Appendage RP11-380L11.4 0.18 0.11 lasso 7 0.12 6.5e-06 7.7 8.6 1.1e-17 -0.07 0.82 0.01 FALSE
35 GTEx Heart Left Ventricle CCDC92 0.26 0.19 lasso 4 0.21 1.9e-11 6.6 8.5 1.5e-17 -0.06 1.00 0.00 FALSE
36 GTEx Lung CDK2AP1 0.08 0.03 lasso 4 0.00 2.0e-01 4.3 -5.5 3.8e-08 0.12 0.58 0.05 FALSE
37 GTEx Lung CCDC92 0.14 0.00 enet 10 0.01 1.1e-01 9.5 9.9 6.1e-23 -0.08 0.00 0.98 FALSE
38 GTEx Lung RP11-380L11.4 0.07 0.07 lasso 3 0.07 8.2e-06 7.8 7.6 3.2e-14 -0.06 0.94 0.00 FALSE
39 GTEx Muscle Skeletal RSRC2 0.06 0.03 enet 7 0.04 9.6e-05 -5.0 -8.1 6.5e-16 0.43 0.25 0.48 TRUE
40 GTEx Muscle Skeletal SETD8 0.16 0.02 lasso 4 0.03 3.8e-04 4.5 6.0 2.6e-09 -0.13 0.81 0.02 FALSE
41 GTEx Muscle Skeletal RP11-380L11.4 0.14 0.03 lasso 8 0.03 4.0e-04 7.6 5.6 2.6e-08 -0.04 0.88 0.00 FALSE
42 GTEx Muscle Skeletal RP11-347I19.8 0.08 0.06 lasso 4 0.06 2.4e-06 3.3 -5.5 5.0e-08 0.03 0.96 0.00 FALSE
43 GTEx Nerve Tibial CCDC92 0.16 0.01 enet 6 0.04 6.7e-04 6.4 9.3 1.6e-20 -0.10 0.12 0.41 FALSE
44 GTEx Nerve Tibial KNTC1 0.12 0.05 lasso 5 0.05 1.9e-04 -5.7 -6.7 2.7e-11 0.31 0.53 0.03 FALSE
45 GTEx Pancreas RP11-347I19.8 0.12 0.00 enet 13 0.00 2.9e-01 3.8 -5.6 1.6e-08 0.00 0.10 0.05 FALSE
46 GTEx Prostate CCDC92 0.31 0.10 enet 42 0.11 9.0e-04 6.3 6.4 1.2e-10 -0.08 0.21 0.05 FALSE
47 GTEx Skin Not Sun Exposed Suprapubic KNTC1 0.11 0.04 lasso 4 0.03 7.1e-03 5.5 -5.3 1.2e-07 0.14 0.22 0.04 FALSE
48 GTEx Skin Sun Exposed Lower leg DDX55 0.13 0.05 enet 13 0.10 1.6e-08 -4.5 5.9 2.9e-09 -0.13 1.00 0.00 FALSE
49 GTEx Skin Sun Exposed Lower leg CCDC92 0.11 0.00 enet 15 0.01 1.0e-01 7.5 5.2 1.7e-07 -0.12 0.08 0.38 FALSE
50 GTEx Skin Sun Exposed Lower leg WDR66 0.19 0.10 lasso 5 0.08 5.5e-07 3.1 5.3 1.0e-07 -0.11 0.98 0.00 FALSE
51 GTEx Skin Sun Exposed Lower leg RP11-380L11.4 0.04 0.02 enet 15 0.02 1.9e-02 7.7 6.5 9.5e-11 -0.04 0.41 0.03 FALSE
52 GTEx Stomach AC084018.1 0.13 0.13 enet 23 0.13 8.7e-07 3.7 -5.4 7.9e-08 -0.01 0.79 0.02 TRUE
53 GTEx Stomach RP11-347I19.8 0.22 0.09 lasso 7 0.11 4.2e-06 3.7 -5.5 4.6e-08 -0.02 0.95 0.01 FALSE
54 GTEx Testis ABCB9 0.14 0.05 lasso 3 0.06 8.0e-04 7.7 -8.6 6.3e-18 0.22 0.25 0.05 TRUE
55 GTEx Testis RP11-282O18.3 0.18 0.09 lasso 9 0.12 7.8e-06 4.4 -6.0 1.9e-09 0.14 0.36 0.04 FALSE
56 GTEx Thyroid CCDC92 0.06 0.03 lasso 3 0.02 1.1e-02 7.6 9.2 3.6e-20 -0.08 0.53 0.05 FALSE
57 GTEx Thyroid WDR66 0.11 0.02 lasso 6 0.02 1.1e-02 -4.1 5.5 3.3e-08 -0.01 0.13 0.13 TRUE
58 GTEx Thyroid ZNF664 0.13 0.06 lasso 11 0.08 6.7e-07 6.3 -7.5 9.2e-14 0.04 1.00 0.00 FALSE
59 GTEx Whole Blood DDX55 0.13 0.04 enet 13 0.06 3.3e-06 -4.4 6.3 2.5e-10 -0.17 0.34 0.02 FALSE
60 METSIM Adipose ABCB9 0.04 0.03 enet 19 0.03 7.7e-05 -5.4 -6.8 1.5e-11 0.38 0.08 0.65 FALSE
61 METSIM Adipose CCDC92 0.10 0.01 bslmm 435 0.06 5.5e-10 -4.8 10.3 6.8e-25 -0.08 0.01 0.99 FALSE
62 METSIM Adipose CLIP1 0.03 0.01 bslmm 372 0.01 3.3e-03 -6.1 5.5 3.9e-08 -0.31 0.60 0.04 TRUE
63 METSIM Adipose DNAH10 0.03 0.00 bslmm 475 0.01 3.2e-03 8.2 6.5 6.7e-11 -0.01 0.04 0.81 FALSE
64 METSIM Adipose LRRC43 0.05 0.05 lasso 2 0.04 7.3e-07 -5.3 -5.3 9.7e-08 0.09 0.96 0.00 FALSE
65 METSIM Adipose MLXIP 0.08 0.07 enet 25 0.07 2.3e-10 -7.0 6.4 1.3e-10 -0.07 1.00 0.00 FALSE
66 METSIM Adipose RP11-214K3.24 0.05 0.03 bslmm 444 0.02 2.7e-04 6.6 8.9 3.7e-19 -0.07 0.57 0.05 FALSE
67 METSIM Adipose TCTN2 0.22 0.11 blup 395 0.12 2.0e-17 -3.0 -6.4 1.2e-10 0.10 1.00 0.00 FALSE
68 YFS Blood NCOR2 0.06 0.00 blup 591 0.02 3.7e-08 -1.1 5.2 2.4e-07 0.03 0.34 0.04 TRUE
69 YFS Blood PSMD9 0.04 0.03 bslmm 324 0.05 8.2e-15 -5.7 5.2 2.0e-07 -0.08 1.00 0.00 FALSE
70 YFS Blood RILPL2 0.37 0.15 enet 28 0.17 1.3e-53 -6.3 -5.2 2.2e-07 0.09 1.00 0.00 TRUE
71 The Cancer Genome Atlas Bladder Urothelial Carcinoma LRRC43 0.06 0.03 enet 6 0.03 8.7e-04 -5.5 -6.7 2.9e-11 0.10 0.13 0.22 FALSE
72 The Cancer Genome Atlas Breast Invasive Carcinoma DNAH10 0.11 0.03 blup 99 0.05 8.2e-11 6.6 7.9 2.1e-15 -0.05 0.12 0.88 FALSE
73 The Cancer Genome Atlas Breast Invasive Carcinoma LRRC43 0.04 0.04 lasso 2 0.04 3.0e-08 -5.3 -5.3 9.4e-08 0.09 1.00 0.00 FALSE
74 The Cancer Genome Atlas Breast Invasive Carcinoma VPS33A 0.01 0.02 lasso 2 0.02 2.7e-04 5.7 -5.7 9.0e-09 0.14 0.33 0.24 FALSE
75 The Cancer Genome Atlas Colon Adenocarcinoma MLXIP 0.06 0.04 lasso 7 0.02 2.7e-02 9.7 9.6 6.8e-22 -0.17 0.02 0.94 FALSE
76 The Cancer Genome Atlas Glioblastoma Multiforme CCDC92 0.07 0.02 blup 52 0.04 1.8e-02 6.3 7.0 3.6e-12 -0.05 0.08 0.05 FALSE
77 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma DNAH10 0.07 0.03 lasso 3 0.05 7.4e-06 7.7 7.7 1.9e-14 -0.06 0.04 0.95 FALSE
78 The Cancer Genome Atlas Brain Lower Grade Glioma LRRC43 0.03 0.03 enet 8 0.02 1.5e-03 -5.3 -6.6 3.3e-11 0.15 0.10 0.06 FALSE
79 The Cancer Genome Atlas Brain Lower Grade Glioma VPS33A 0.03 0.05 lasso 1 0.05 4.4e-06 5.4 -5.4 5.7e-08 0.13 0.93 0.03 FALSE
80 The Cancer Genome Atlas Prostate Adenocarcinoma GPR109A 0.03 0.01 blup 21 0.01 1.3e-02 -3.8 -6.0 2.4e-09 0.29 0.05 0.03 FALSE
81 The Cancer Genome Atlas Prostate Adenocarcinoma GPR81 0.07 0.02 blup 54 0.02 4.4e-03 5.7 5.4 7.4e-08 -0.13 0.04 0.20 FALSE
82 The Cancer Genome Atlas Prostate Adenocarcinoma LRRC43 0.04 0.00 blup 58 0.01 6.9e-02 8.6 -6.3 2.6e-10 0.12 0.02 0.19 FALSE
83 The Cancer Genome Atlas Prostate Adenocarcinoma VPS33A 0.04 0.05 lasso 1 0.04 3.0e-05 5.7 -5.7 1.6e-08 0.13 0.88 0.11 FALSE
84 The Cancer Genome Atlas Rectum Adenocarcinoma MLXIP 0.18 0.14 lasso 4 0.13 5.1e-04 8.8 9.2 2.4e-20 -0.16 0.02 0.89 FALSE
85 The Cancer Genome Atlas Stomach Adenocarcinoma MLXIP 0.06 0.02 blup 68 0.04 1.2e-03 9.7 11.2 4.0e-29 -0.23 0.02 0.89 TRUE
86 The Cancer Genome Atlas Thyroid Carcinoma DNAH10 0.04 0.03 lasso 5 0.02 4.6e-03 6.4 7.3 3.7e-13 -0.05 0.02 0.83 FALSE
87 The Cancer Genome Atlas Thyroid Carcinoma PSMD9 0.09 0.10 lasso 4 0.10 7.4e-10 -5.7 5.7 1.6e-08 -0.02 0.01 0.99 FALSE
88 The Cancer Genome Atlas Thyroid Carcinoma VPS33A 0.06 0.00 enet 8 0.03 9.6e-04 5.0 -7.2 6.3e-13 0.20 0.06 0.94 FALSE
89 The Cancer Genome Atlas Thyroid Carcinoma ZNF664 0.06 0.05 enet 9 0.05 2.8e-05 7.6 -7.9 2.2e-15 0.08 0.94 0.00 FALSE