Best TWAS P=1.37e-08 · Best GWAS P=1.54e-06 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Breast Mammary Tissue (Male) | CDC16 | 0.23 | 0.08 | enet | 11 | 0.09 | 3.8e-03 | -4.7 | -5.7 | 1.4e-08 | 0.85 | 0.02 | 0.83 | TRUE |
| 2 | GTEx | Breast Mammary Tissue (Female) | UPF3A | 0.32 | 0.16 | lasso | 13 | 0.17 | 1.2e-05 | -4.7 | -5.3 | 1.3e-07 | 0.91 | 0.02 | 0.96 | FALSE |
| 3 | The Cancer Genome Atlas | Breast Invasive Carcinoma | CDC16 | 0.01 | 0.01 | blup | 49 | 0.01 | 1.1e-03 | -4.6 | -5.2 | 2.3e-07 | 0.97 | 0.02 | 0.91 | FALSE |
| 4 | The Cancer Genome Atlas | Pheochromocytoma and Paraganglioma | CDC16 | 0.07 | 0.03 | blup | 49 | 0.05 | 6.3e-03 | -4.8 | -5.2 | 2.3e-07 | 0.93 | 0.01 | 0.75 | FALSE |