Best TWAS P=2.41e-09 · Best GWAS P=1.54e-10 conditioned to 0.000128
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Brain Frontal Cortex BA9 | TEX29 | 0.45 | 0.10 | lasso | 8 | 0.24 | 4.2e-07 | -4.3 | -6.0 | 2.4e-09 | -0.40 | 0.06 | 0.49 | TRUE |
| 2 | The Cancer Genome Atlas | Brain Lower Grade Glioma | ARHGEF7 | 0.09 | 0.07 | blup | 142 | 0.08 | 3.1e-09 | -4.7 | 5.7 | 1.1e-08 | 0.39 | 0.94 | 0.06 | TRUE |