Best TWAS P=3.75e-08 · Best GWAS P=1.79e-14 conditioned to 2.57e-05
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Muscle Skeletal | C14orf39 | 0.06 | 0.05 | lasso | 3 | 0.05 | 2.7e-05 | 3.5 | -5.3 | 1.4e-07 | -0.59 | 0.31 | 0.66 | FALSE |
| 2 | GTEx | Skin Not Sun Exposed Suprapubic | PCNXL4 | 0.15 | 0.05 | enet | 15 | 0.12 | 6.2e-07 | 1.6 | -5.5 | 4.4e-08 | -0.59 | 0.27 | 0.68 | TRUE |
| 3 | The Cancer Genome Atlas | Lung Adenocarcinoma | C14orf39 | 0.02 | 0.02 | blup | 37 | 0.02 | 4.2e-03 | 3.4 | -5.5 | 3.7e-08 | -0.54 | 0.08 | 0.30 | TRUE |
| 4 | The Cancer Genome Atlas | Pheochromocytoma and Paraganglioma | C14orf39 | 0.08 | 0.05 | blup | 37 | 0.05 | 4.2e-03 | 4.0 | -5.3 | 1.1e-07 | -0.52 | 0.07 | 0.50 | FALSE |
| 5 | The Cancer Genome Atlas | Prostate Adenocarcinoma | C14orf39 | 0.08 | 0.09 | blup | 37 | 0.11 | 1.8e-11 | 4.1 | -5.1 | 3.1e-07 | -0.50 | 1.00 | 0.00 | FALSE |