Best TWAS P=1.23e-07 · Best GWAS P=8.41e-08 conditioned to 0.0277
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Cells EBV-transformed lymphocytes | PIP5K1C | 0.25 | 0.14 | lasso | 4 | 0.18 | 1.8e-06 | -3.3 | -5.2 | 1.8e-07 | 0.32 | 0.17 | 0.24 | TRUE |
| 2 | GTEx | Colon Sigmoid | MAP2K2 | 0.20 | 0.11 | lasso | 3 | 0.13 | 3.0e-05 | -4.8 | -5.3 | 1.2e-07 | 0.71 | 0.02 | 0.87 | TRUE |