Best TWAS P=8.86e-10 · Best GWAS P=1.1e-11 conditioned to 0.206
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Muscle Skeletal | SLC44A2 | 0.19 | 0.18 | lasso | 5 | 0.19 | 5.1e-18 | 5.5 | 5.9 | 4.0e-09 | 0.76 | 0.92 | 0.08 | FALSE |
| 2 | GTEx | Pituitary | CDC37 | 0.23 | 0.11 | lasso | 5 | 0.05 | 2.3e-02 | 4.4 | 5.3 | 1.0e-07 | 0.26 | 0.07 | 0.39 | TRUE |
| 3 | The Cancer Genome Atlas | Brain Lower Grade Glioma | LOC147727 | 0.07 | 0.02 | lasso | 2 | 0.02 | 5.4e-03 | 5.9 | -6.1 | 8.9e-10 | -0.93 | 0.06 | 0.23 | TRUE |
| 4 | The Cancer Genome Atlas | Thyroid Carcinoma | SLC44A2 | 0.32 | 0.22 | enet | 14 | 0.25 | 3.8e-24 | 6.8 | 5.4 | 5.7e-08 | 0.93 | 0.01 | 0.99 | FALSE |