Best TWAS P=2.84e-08 · Best GWAS P=9.5e-08 conditioned to 1.65e-06
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Breast Mammary Tissue | PSMG1 | 0.28 | 0.26 | lasso | 4 | 0.23 | 5.2e-12 | -5.2 | 5.1 | 3.0e-07 | 0.02 | 0.03 | 0.97 | FALSE |
| 2 | GTEx | Breast Mammary Tissue (Female) | PSMG1 | 0.14 | 0.09 | lasso | 11 | 0.07 | 3.3e-03 | -5.2 | 5.4 | 8.4e-08 | 0.03 | 0.05 | 0.85 | FALSE |
| 3 | GTEx | Colon Sigmoid | PSMG1 | 0.29 | 0.16 | lasso | 15 | 0.21 | 6.5e-08 | -4.9 | 5.2 | 1.5e-07 | 0.01 | 0.04 | 0.96 | FALSE |
| 4 | GTEx | Skin Not Sun Exposed Suprapubic | PSMG1 | 0.26 | 0.34 | lasso | 5 | 0.34 | 2.1e-19 | -5.2 | 5.1 | 2.8e-07 | 0.03 | 0.03 | 0.97 | FALSE |
| 5 | GTEx | Skin Sun Exposed Lower leg | PSMG1 | 0.32 | 0.38 | lasso | 3 | 0.38 | 5.5e-33 | -5.2 | 5.2 | 2.5e-07 | 0.03 | 0.02 | 0.97 | FALSE |
| 6 | GTEx | Skin Sun Exposed Lower leg | BRWD1 | 0.09 | 0.05 | lasso | 8 | 0.04 | 4.9e-04 | -5.0 | 5.6 | 2.8e-08 | -0.10 | 0.04 | 0.88 | TRUE |