Best TWAS P=2.98e-08 · Best GWAS P=7.21e-09 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Subcutaneous | TOM1 | 0.09 | 0.06 | lasso | 4 | 0.05 | 4.4e-05 | -4.9 | -5.4 | 5.6e-08 | 0.96 | 0.02 | 0.98 | FALSE |
| 2 | GTEx | Muscle Skeletal | TOM1 | 0.16 | 0.13 | lasso | 15 | 0.11 | 3.1e-11 | -5.7 | -5.5 | 3.0e-08 | 0.99 | 0.02 | 0.98 | TRUE |
| 3 | NTR | Blood | TOM1 | 0.05 | 0.05 | lasso | 5 | 0.06 | 2.3e-17 | -5.7 | -5.2 | 2.1e-07 | 0.95 | 0.02 | 0.98 | FALSE |
| 4 | The Cancer Genome Atlas | Breast Invasive Carcinoma | HMGXB4 | 0.01 | 0.01 | blup | 59 | 0.01 | 8.3e-03 | -5.7 | -5.3 | 1.1e-07 | 0.97 | 0.02 | 0.84 | FALSE |
| 5 | The Cancer Genome Atlas | Thyroid Carcinoma | TOM1 | 0.03 | 0.03 | blup | 65 | 0.02 | 1.7e-03 | -5.1 | -5.3 | 1.0e-07 | 0.89 | 0.02 | 0.79 | FALSE |