[Hub]/) : Traits : Hip circumference :

chr22:37,918,116-40,479,448

Best TWAS P=5.98e-12 · Best GWAS P=5.21e-08 conditioned to 0.00407

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex DDX17 0.04 0.02 lasso 6 0.03 1.2e-04 4.6 5.3 9.0e-08 -0.03 0.07 0.92 FALSE
2 GTEx Artery Aorta DDX17 0.07 0.03 lasso 4 0.04 2.1e-03 5.0 5.3 9.0e-08 0.01 0.07 0.84 FALSE
3 GTEx Artery Aorta TMEM184B 0.17 0.07 enet 34 0.03 1.2e-02 4.8 -5.2 2.6e-07 -0.50 0.09 0.56 FALSE
4 GTEx Artery Aorta AL021977.1 0.13 0.00 enet 17 0.01 8.7e-02 4.6 -5.9 3.2e-09 -0.47 0.06 0.47 TRUE
5 GTEx Artery Coronary CBY1 0.26 0.20 lasso 4 0.22 8.3e-08 4.9 -5.2 2.6e-07 0.05 0.07 0.93 FALSE
6 GTEx Artery Tibial RP3-508I15.9 0.18 0.21 lasso 8 0.21 1.3e-16 4.9 -5.2 2.4e-07 0.05 0.07 0.93 FALSE
7 GTEx Brain Cortex RP3-508I15.9 0.21 0.12 lasso 7 0.10 1.1e-03 5.0 -5.3 1.1e-07 0.05 0.06 0.90 FALSE
8 GTEx Cells Transformed fibroblasts RP3-508I15.9 0.31 0.43 lasso 15 0.43 6.2e-35 5.1 -5.2 2.7e-07 0.06 0.05 0.94 FALSE
9 GTEx Esophagus Mucosa SUN2 0.12 0.14 lasso 3 0.14 1.3e-09 4.9 -5.4 7.2e-08 0.04 0.05 0.95 FALSE
10 GTEx Esophagus Muscularis RP3-508I15.9 0.13 0.12 enet 23 0.10 1.1e-06 4.9 -5.2 1.7e-07 0.06 0.06 0.94 FALSE
11 GTEx Lung TOMM22 0.05 0.04 enet 11 0.04 3.8e-04 4.6 -5.3 8.6e-08 -0.10 0.06 0.91 FALSE
12 GTEx Nerve Tibial TOMM22 0.11 0.08 lasso 4 0.08 5.2e-06 5.1 -5.8 7.7e-09 0.04 0.07 0.90 FALSE
13 GTEx Skin Not Sun Exposed Suprapubic SUN2 0.13 0.00 enet 36 0.02 2.9e-02 5.2 -6.9 6.0e-12 -0.12 0.04 0.91 TRUE
14 GTEx Skin Not Sun Exposed Suprapubic RP3-508I15.19 0.14 0.06 enet 39 0.03 7.8e-03 5.2 -6.3 3.2e-10 -0.02 0.04 0.92 FALSE
15 GTEx Skin Sun Exposed Lower leg JOSD1 0.09 0.15 lasso 2 0.14 1.7e-11 5.1 -5.1 2.8e-07 0.07 0.05 0.95 FALSE
16 GTEx Spleen SYNGR1 0.36 0.41 lasso 2 0.36 3.4e-10 5.2 5.2 2.4e-07 0.02 0.00 1.00 TRUE
17 GTEx Testis RP3-508I15.9 0.13 0.11 lasso 4 0.13 1.6e-06 4.9 -5.3 1.4e-07 0.04 0.06 0.93 FALSE
18 The Cancer Genome Atlas Breast Invasive Carcinoma SUN2 0.01 0.00 blup 60 0.00 1.4e-01 -3.1 -5.2 2.5e-07 0.02 0.01 0.23 FALSE
19 The Cancer Genome Atlas Colon Adenocarcinoma CBY1 0.07 0.11 enet 18 0.10 1.2e-06 5.0 5.1 3.1e-07 -0.07 0.02 0.97 FALSE
20 The Cancer Genome Atlas Colon Adenocarcinoma JOSD1 0.05 0.02 blup 50 0.04 2.7e-03 4.8 -5.3 1.4e-07 0.06 0.04 0.80 FALSE
21 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma JOSD1 0.08 0.03 enet 5 0.04 3.4e-05 4.3 -5.1 3.0e-07 0.06 0.06 0.92 FALSE
22 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma LOC646851 0.02 0.03 lasso 1 0.02 1.2e-03 5.2 5.2 2.6e-07 -0.07 0.02 0.81 FALSE
23 The Cancer Genome Atlas Lung Adenocarcinoma TOMM22 0.02 0.02 blup 43 0.02 1.7e-03 5.1 -5.2 2.1e-07 0.06 0.02 0.86 FALSE
24 The Cancer Genome Atlas Pancreatic Adenocarcinoma LOC646851 0.08 0.06 blup 47 0.07 8.1e-04 4.6 5.2 2.3e-07 -0.06 0.03 0.91 FALSE
25 The Cancer Genome Atlas Prostate Adenocarcinoma LOC646851 0.03 0.03 blup 48 0.03 2.7e-04 4.6 5.2 2.4e-07 -0.07 0.03 0.93 FALSE
26 The Cancer Genome Atlas Thyroid Carcinoma PDGFB 0.08 0.01 blup 59 0.03 1.1e-03 4.9 -5.2 2.2e-07 -0.03 0.00 0.52 TRUE
27 The Cancer Genome Atlas Thyroid Carcinoma TOMM22 0.06 0.04 lasso 3 0.04 1.1e-04 5.1 -5.4 5.6e-08 0.04 0.02 0.97 FALSE