[Hub]/) : Traits : Hip circumference : ← →

chr1:10,428,952-12,731,572

Best TWAS P=4.71e-11 · Best GWAS P=1.25e-08 conditioned to 0.84

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	EXOSC10	0.06	0.08	lasso	2	0.07	6.8e-09	5.3	5.3	1.4e-07	0.92	0.08	0.92	FALSE
2	GTEx	Brain Cerebellar Hemisphere	EXOSC10	0.23	0.10	lasso	3	0.12	6.4e-04	4.9	5.6	2.4e-08	0.97	0.02	0.90	FALSE
3	GTEx	Brain Cerebellum	EXOSC10	0.33	0.16	lasso	6	0.18	3.8e-06	5.2	5.5	4.8e-08	0.93	0.04	0.95	FALSE
4	GTEx	Brain Cerebellum	RP4-635E18.7	0.17	0.17	lasso	5	0.09	1.3e-03	5.2	5.4	7.3e-08	0.91	0.05	0.88	FALSE
5	GTEx	Cells Transformed fibroblasts	CLCN6	0.08	0.02	enet	17	0.05	1.6e-04	5.2	5.1	3.0e-07	0.08	0.03	0.96	FALSE
6	GTEx	Lung	EXOSC10	0.11	0.07	lasso	4	0.05	1.2e-04	5.2	5.1	3.1e-07	0.89	0.10	0.89	FALSE
7	GTEx	Skin Not Sun Exposed Suprapubic	CLCN6	0.12	0.03	lasso	3	0.04	3.3e-03	5.5	5.9	2.8e-09	0.12	0.01	0.96	FALSE
8	GTEx	Thyroid	RP4-635E18.7	0.07	0.02	lasso	2	0.01	5.5e-02	5.2	5.2	1.6e-07	0.86	0.06	0.64	FALSE
9	ROSMAP	Brain Pre-frontal Cortex	PLOD1	0.11	0.03	blup	459	0.05	1.3e-07	4.3	5.4	8.0e-08	0.09	0.46	0.51	FALSE
10	ROSMAP	Brain Pre-frontal Cortex	EXOSC10	0.06	0.06	lasso	2	0.06	4.9e-08	5.3	5.3	1.2e-07	0.92	0.07	0.93	FALSE
11	ROSMAP	Brain Pre-frontal Cortex	MTOR	0.07	0.05	bslmm	423	0.04	2.0e-06	4.7	5.9	2.8e-09	0.87	0.24	0.76	TRUE
12	The Cancer Genome Atlas	Breast Invasive Carcinoma	CLCN6	0.06	0.06	blup	104	0.06	5.0e-12	3.5	5.3	1.2e-07	0.07	0.47	0.51	FALSE
13	The Cancer Genome Atlas	Colon Adenocarcinoma	CLCN6	0.14	0.05	blup	104	0.09	1.2e-05	5.2	5.9	3.4e-09	0.14	0.03	0.96	FALSE
14	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	MTOR	0.02	0.02	blup	54	0.02	5.4e-03	5.6	5.6	1.8e-08	0.97	0.02	0.90	FALSE
15	The Cancer Genome Atlas	Brain Lower Grade Glioma	MTOR	0.03	0.01	blup	54	0.02	5.9e-03	5.6	5.5	2.9e-08	0.93	0.03	0.70	FALSE
16	The Cancer Genome Atlas	Lung Adenocarcinoma	CLCN6	0.06	0.04	blup	104	0.04	5.2e-06	5.2	5.6	2.6e-08	0.10	0.01	0.98	FALSE
17	The Cancer Genome Atlas	Thyroid Carcinoma	CLCN6	0.08	0.02	blup	104	0.05	2.5e-05	4.5	6.6	4.7e-11	0.06	0.15	0.83	TRUE