Best TWAS P=3.78e-28 · Best GWAS P=6.29e-28 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Subcutaneous | ZBTB38 | 0.08 | 0.04 | lasso | 4 | 0.03 | 8.1e-04 | 11.0 | 11.0 | 3.8e-28 | 0.98 | 0.01 | 0.99 | TRUE |
| 2 | GTEx | Testis | ZBTB38 | 0.14 | 0.06 | lasso | 8 | 0.05 | 2.8e-03 | 9.2 | 9.7 | 4.6e-22 | 0.60 | 0.23 | 0.62 | FALSE |
| 3 | GTEx | Thyroid | ZBTB38 | 0.11 | 0.03 | enet | 32 | 0.04 | 2.9e-04 | 7.6 | 8.0 | 9.2e-16 | 0.62 | 0.07 | 0.92 | FALSE |
| 4 | NTR | Blood | ZBTB38 | 0.03 | 0.01 | lasso | 3 | 0.01 | 2.2e-05 | 10.8 | 9.2 | 4.3e-20 | 0.88 | 0.01 | 0.99 | FALSE |
| 5 | The Cancer Genome Atlas | Soft Tissue Sarcoma | ZBTB38 | 0.04 | 0.03 | lasso | 3 | 0.04 | 3.0e-03 | 9.5 | 10.4 | 3.0e-25 | 0.59 | 0.04 | 0.40 | TRUE |