Best TWAS P=2.92e-08 · Best GWAS P=2.05e-12 conditioned to 0.000906
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Artery Aorta | CTPS1 | 0.10 | 0.00 | enet | 8 | 0.00 | 4.6e-01 | 4 | 5.2 | 2.5e-07 | 0.07 | 0.03 | 0.72 | TRUE |
2 | GTEx | Brain Cerebellum | HIVEP3 | 0.23 | 0.16 | lasso | 6 | 0.19 | 2.8e-06 | 4 | 5.3 | 9.8e-08 | 0.69 | 0.11 | 0.82 | TRUE |
3 | ROSMAP | Brain Pre-frontal Cortex | RIMKLA | 0.06 | 0.06 | bslmm | 341 | 0.05 | 1.3e-07 | -4 | 5.5 | 2.9e-08 | 0.41 | 0.96 | 0.02 | TRUE |