[Hub]/) : Traits : Hip circumference : ← →

chr1:39,182,130-40,737,589

Best TWAS P=1.52e-10 · Best GWAS P=5.31e-12 conditioned to 0.00208

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
2	GTEx	Adrenal Gland	PABPC4	0.20	0.09	lasso	8	0.06	3.0e-03	5.4	-6.4	1.5e-10	-0.77	0.06	0.78	TRUE
5	GTEx	Breast Mammary Tissue (Female)	PABPC4	0.10	0.00	enet	9	0.01	1.5e-01	6.3	-6.3	3.2e-10	-0.83	0.03	0.47	FALSE
17	NTR	Blood	PABPC4	0.01	0.00	blup	383	0.00	2.8e-02	5.4	-6.2	4.2e-10	-0.68	0.05	0.48	FALSE
16	NTR	Blood	KIAA0754	0.03	0.00	bslmm	366	0.01	1.6e-03	-1.7	5.9	3.5e-09	0.62	0.10	0.75	FALSE
19	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	BMP8A	0.04	0.03	blup	48	0.04	3.5e-05	4.5	5.8	6.2e-09	0.68	0.02	0.97	FALSE
10	GTEx	Nerve Tibial	RP11-69E11.8	0.05	0.00	lasso	3	0.01	6.9e-02	5.4	-5.7	1.1e-08	-0.75	0.03	0.87	FALSE
24	The Cancer Genome Atlas	Thyroid Carcinoma	PABPC4	0.09	0.07	enet	5	0.08	4.1e-08	5.4	-5.7	1.2e-08	-0.62	0.00	1.00	FALSE
1	CommonMind	Brain Pre-frontal Cortex	BMP8A	0.05	0.03	lasso	3	0.02	8.8e-04	5.4	5.6	2.2e-08	0.71	0.07	0.88	FALSE
18	The Cancer Genome Atlas	Breast Invasive Carcinoma	PABPC4	0.03	0.03	lasso	2	0.04	1.3e-08	5.4	-5.6	2.4e-08	-0.62	0.00	1.00	FALSE
22	The Cancer Genome Atlas	Brain Lower Grade Glioma	BMP8A	0.05	0.01	blup	48	0.04	6.8e-05	6.0	5.6	2.6e-08	0.68	0.00	0.98	FALSE
12	GTEx	Skin Not Sun Exposed Suprapubic	PABPC4	0.12	0.10	lasso	3	0.05	1.0e-03	5.4	-5.5	3.0e-08	-0.71	0.28	0.41	FALSE
23	The Cancer Genome Atlas	Lung Adenocarcinoma	PABPC4	0.04	0.03	enet	8	0.04	4.5e-05	5.4	-5.5	3.8e-08	-0.62	0.00	1.00	FALSE
7	GTEx	Esophagus Mucosa	PABPC4	0.06	0.06	lasso	3	0.08	7.3e-06	5.4	-5.5	4.8e-08	-0.73	0.38	0.56	FALSE
14	GTEx	Spleen	RP11-69E11.4	0.25	0.12	lasso	4	0.15	9.3e-05	4.5	5.5	5.0e-08	0.70	0.21	0.53	FALSE
6	GTEx	Cells Transformed fibroblasts	PABPC4	0.07	0.09	lasso	1	0.06	2.7e-05	5.4	-5.4	6.4e-08	-0.68	0.22	0.72	FALSE
4	GTEx	Breast Mammary Tissue	PABPC4	0.13	0.02	enet	14	0.04	3.4e-03	5.4	-5.4	7.8e-08	-0.70	0.08	0.81	FALSE
13	GTEx	Skin Sun Exposed Lower leg	RP11-69E11.4	0.13	0.12	lasso	6	0.15	1.3e-12	5.5	5.3	9.2e-08	0.72	0.92	0.08	FALSE
3	GTEx	Artery Tibial	PABPC4	0.10	0.10	lasso	4	0.10	3.4e-08	5.4	-5.3	1.1e-07	-0.72	0.46	0.54	FALSE
11	GTEx	Ovary	RP11-69E11.4	0.25	0.05	enet	11	0.03	6.7e-02	4.9	5.3	1.1e-07	0.68	0.05	0.43	FALSE
21	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	PABPC4	0.04	0.05	blup	31	0.04	1.2e-05	4.9	-5.2	2.0e-07	-0.57	0.02	0.97	FALSE
15	GTEx	Spleen	BMP8A	0.16	0.08	lasso	3	0.05	1.6e-02	5.5	5.2	2.1e-07	0.75	0.07	0.30	FALSE
20	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	PABPC4	0.03	0.01	enet	4	0.02	4.3e-03	5.4	-5.2	2.1e-07	-0.68	0.00	0.98	FALSE
9	GTEx	Nerve Tibial	PABPC4	0.17	0.08	enet	12	0.05	2.7e-04	5.4	-5.1	2.8e-07	-0.73	0.07	0.93	FALSE
8	GTEx	Lung	PABPC4	0.05	0.03	lasso	3	0.02	1.3e-02	5.4	-5.1	3.0e-07	-0.64	0.12	0.72	FALSE