[Hub]/) : Traits : Hip circumference :

chr1:39,182,130-40,737,589

Best TWAS P=1.52e-10 · Best GWAS P=5.31e-12 conditioned to 0.00208

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex BMP8A 0.05 0.03 lasso 3 0.02 8.8e-04 5.4 5.6 2.2e-08 0.71 0.07 0.88 FALSE
2 GTEx Adrenal Gland PABPC4 0.20 0.09 lasso 8 0.06 3.0e-03 5.4 -6.4 1.5e-10 -0.77 0.06 0.78 TRUE
3 GTEx Artery Tibial PABPC4 0.10 0.10 lasso 4 0.10 3.4e-08 5.4 -5.3 1.1e-07 -0.72 0.46 0.54 FALSE
4 GTEx Breast Mammary Tissue PABPC4 0.13 0.02 enet 14 0.04 3.4e-03 5.4 -5.4 7.8e-08 -0.70 0.08 0.81 FALSE
5 GTEx Breast Mammary Tissue (Female) PABPC4 0.10 0.00 enet 9 0.01 1.5e-01 6.3 -6.3 3.2e-10 -0.83 0.03 0.47 FALSE
6 GTEx Cells Transformed fibroblasts PABPC4 0.07 0.09 lasso 1 0.06 2.7e-05 5.4 -5.4 6.4e-08 -0.68 0.22 0.72 FALSE
7 GTEx Esophagus Mucosa PABPC4 0.06 0.06 lasso 3 0.08 7.3e-06 5.4 -5.5 4.8e-08 -0.73 0.38 0.56 FALSE
8 GTEx Lung PABPC4 0.05 0.03 lasso 3 0.02 1.3e-02 5.4 -5.1 3.0e-07 -0.64 0.12 0.72 FALSE
9 GTEx Nerve Tibial PABPC4 0.17 0.08 enet 12 0.05 2.7e-04 5.4 -5.1 2.8e-07 -0.73 0.07 0.93 FALSE
10 GTEx Nerve Tibial RP11-69E11.8 0.05 0.00 lasso 3 0.01 6.9e-02 5.4 -5.7 1.1e-08 -0.75 0.03 0.87 FALSE
11 GTEx Ovary RP11-69E11.4 0.25 0.05 enet 11 0.03 6.7e-02 4.9 5.3 1.1e-07 0.68 0.05 0.43 FALSE
12 GTEx Skin Not Sun Exposed Suprapubic PABPC4 0.12 0.10 lasso 3 0.05 1.0e-03 5.4 -5.5 3.0e-08 -0.71 0.28 0.41 FALSE
13 GTEx Skin Sun Exposed Lower leg RP11-69E11.4 0.13 0.12 lasso 6 0.15 1.3e-12 5.5 5.3 9.2e-08 0.72 0.92 0.08 FALSE
14 GTEx Spleen RP11-69E11.4 0.25 0.12 lasso 4 0.15 9.3e-05 4.5 5.5 5.0e-08 0.70 0.21 0.53 FALSE
15 GTEx Spleen BMP8A 0.16 0.08 lasso 3 0.05 1.6e-02 5.5 5.2 2.1e-07 0.75 0.07 0.30 FALSE
16 NTR Blood KIAA0754 0.03 0.00 bslmm 366 0.01 1.6e-03 -1.7 5.9 3.5e-09 0.62 0.10 0.75 FALSE
17 NTR Blood PABPC4 0.01 0.00 blup 383 0.00 2.8e-02 5.4 -6.2 4.2e-10 -0.68 0.05 0.48 FALSE
18 The Cancer Genome Atlas Breast Invasive Carcinoma PABPC4 0.03 0.03 lasso 2 0.04 1.3e-08 5.4 -5.6 2.4e-08 -0.62 0.00 1.00 FALSE
19 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma BMP8A 0.04 0.03 blup 48 0.04 3.5e-05 4.5 5.8 6.2e-09 0.68 0.02 0.97 FALSE
20 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma PABPC4 0.03 0.01 enet 4 0.02 4.3e-03 5.4 -5.2 2.1e-07 -0.68 0.00 0.98 FALSE
21 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma PABPC4 0.04 0.05 blup 31 0.04 1.2e-05 4.9 -5.2 2.0e-07 -0.57 0.02 0.97 FALSE
22 The Cancer Genome Atlas Brain Lower Grade Glioma BMP8A 0.05 0.01 blup 48 0.04 6.8e-05 6.0 5.6 2.6e-08 0.68 0.00 0.98 FALSE
23 The Cancer Genome Atlas Lung Adenocarcinoma PABPC4 0.04 0.03 enet 8 0.04 4.5e-05 5.4 -5.5 3.8e-08 -0.62 0.00 1.00 FALSE
24 The Cancer Genome Atlas Thyroid Carcinoma PABPC4 0.09 0.07 enet 5 0.08 4.1e-08 5.4 -5.7 1.2e-08 -0.62 0.00 1.00 FALSE