Best TWAS P=6.46e-14 · Best GWAS P=7.06e-18 conditioned to 1.31e-06
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | The Cancer Genome Atlas | Breast Invasive Carcinoma | RSPO3 | 0.02 | 0.02 | blup | 60 | 0.02 | 0.00028 | -6.1 | -7.5 | 6.5e-14 | 0.67 | 0.27 | 0.17 | TRUE |
| 2 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | RSPO3 | 0.02 | 0.03 | blup | 60 | 0.02 | 0.00132 | -5.6 | -7.2 | 7.4e-13 | 0.62 | 0.37 | 0.16 | FALSE |