Best TWAS P=7.47e-12 · Best GWAS P=8.04e-45 conditioned to 3.27e-43
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Esophagus Mucosa | RMND1 | 0.34 | 0.09 | lasso | 6 | 0.19 | 4.8e-13 | 5.8 | -6.3 | 3.6e-10 | 0.00 | 1.00 | 0.00 | FALSE |
| 2 | GTEx | Lung | RMND1 | 0.26 | 0.14 | lasso | 7 | 0.15 | 1.7e-11 | 6.1 | -6.2 | 4.2e-10 | -0.02 | 1.00 | 0.00 | FALSE |
| 3 | GTEx | Thyroid | RMND1 | 0.17 | 0.12 | lasso | 4 | 0.13 | 2.4e-10 | 6.1 | -6.3 | 3.7e-10 | -0.02 | 0.99 | 0.00 | FALSE |
| 4 | YFS | Blood | RMND1 | 0.06 | 0.06 | lasso | 12 | 0.05 | 6.5e-16 | 5.4 | -6.0 | 1.5e-09 | 0.00 | 1.00 | 0.00 | FALSE |
| 5 | The Cancer Genome Atlas | Breast Invasive Carcinoma | RMND1 | 0.02 | 0.00 | blup | 57 | 0.01 | 3.1e-03 | 4.3 | -5.9 | 4.7e-09 | -0.02 | 0.00 | 0.62 | FALSE |
| 6 | The Cancer Genome Atlas | Cervical Squamous Cell Carcinoma | RMND1 | 0.16 | 0.10 | lasso | 7 | 0.12 | 1.6e-06 | 5.4 | -6.0 | 1.7e-09 | -0.01 | 0.02 | 0.98 | FALSE |
| 7 | The Cancer Genome Atlas | Colon Adenocarcinoma | RMND1 | 0.11 | 0.09 | lasso | 4 | 0.10 | 2.9e-06 | 5.7 | -5.8 | 6.2e-09 | 0.02 | 0.15 | 0.83 | FALSE |
| 8 | The Cancer Genome Atlas | Esophageal Carcinoma | RMND1 | 0.12 | 0.09 | enet | 9 | 0.10 | 4.2e-04 | 4.8 | -6.0 | 1.9e-09 | -0.02 | 0.06 | 0.44 | FALSE |
| 9 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | RMND1 | 0.07 | 0.06 | blup | 58 | 0.09 | 1.4e-10 | 5.4 | -6.1 | 8.6e-10 | 0.02 | 0.17 | 0.83 | FALSE |
| 10 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | RMND1 | 0.09 | 0.10 | lasso | 4 | 0.10 | 1.6e-11 | 5.1 | -5.8 | 7.8e-09 | 0.04 | 0.57 | 0.43 | FALSE |
| 11 | The Cancer Genome Atlas | Lung Adenocarcinoma | RMND1 | 0.05 | 0.06 | lasso | 2 | 0.07 | 4.3e-08 | 6.5 | -6.8 | 7.5e-12 | -0.04 | 0.00 | 1.00 | TRUE |
| 12 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | RMND1 | 0.09 | 0.02 | lasso | 6 | 0.03 | 2.3e-04 | 6.1 | -6.0 | 1.5e-09 | 0.01 | 0.04 | 0.95 | FALSE |
| 13 | The Cancer Genome Atlas | Prostate Adenocarcinoma | RMND1 | 0.22 | 0.21 | enet | 15 | 0.26 | 2.4e-27 | 6.1 | -5.7 | 1.1e-08 | -0.03 | 0.02 | 0.98 | FALSE |
| 14 | The Cancer Genome Atlas | Skin Cutaneous Melanoma | RMND1 | 0.16 | 0.15 | enet | 7 | 0.09 | 2.7e-03 | 6.5 | -6.0 | 1.6e-09 | -0.04 | 0.01 | 0.95 | FALSE |
| 15 | The Cancer Genome Atlas | Stomach Adenocarcinoma | RMND1 | 0.06 | 0.04 | blup | 57 | 0.06 | 4.9e-05 | 6.1 | -6.5 | 8.1e-11 | -0.02 | 0.02 | 0.93 | FALSE |
| 16 | The Cancer Genome Atlas | Thyroid Carcinoma | RMND1 | 0.13 | 0.13 | enet | 6 | 0.14 | 6.6e-14 | 5.8 | -5.5 | 2.8e-08 | 0.02 | 0.15 | 0.85 | FALSE |