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chr6:141,787,794-143,855,272

Best TWAS P=1.33e-111 · Best GWAS P=5.7e-118 conditioned to 1

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Adipose Subcutaneous	GPR126	0.06	0.04	lasso	4	0.04	6.1e-04	-22.1	22.4	1.3e-111	-0.97	0.02	0.95	TRUE
3	METSIM	Adipose	GPR126	0.05	0.01	blup	429	0.02	1.9e-04	-11.2	18.5	2.2e-76	-0.74	0.12	0.87	TRUE
5	NTR	Blood	HIVEP2	0.02	0.01	blup	424	0.01	2.6e-03	-8.3	-13.3	1.6e-40	0.40	0.34	0.05	TRUE
14	The Cancer Genome Atlas	Uterine Corpus Endometrial Carcinoma	NMBR	0.09	0.01	blup	46	0.04	3.4e-02	8.5	-10.5	1.4e-25	0.11	0.01	0.67	TRUE
2	GTEx	Colon Transverse	GPR126	0.13	-0.01	lasso	7	0.00	4.2e-01	-9.5	-8.0	1.5e-15	0.32	0.07	0.37	TRUE
8	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	NMBR	0.04	0.04	enet	9	0.03	1.7e-04	8.1	-7.8	5.5e-15	0.11	0.37	0.07	TRUE
4	METSIM	Adipose	VTA1	0.03	0.03	lasso	5	0.02	9.8e-04	-7.5	-5.8	6.0e-09	0.04	0.62	0.01	TRUE
11	The Cancer Genome Atlas	Prostate Adenocarcinoma	VTA1	0.03	0.00	enet	8	0.00	1.1e-01	10.2	-5.5	3.6e-08	0.15	0.09	0.13	TRUE
12	The Cancer Genome Atlas	Thyroid Carcinoma	NMBR	0.06	0.04	blup	46	0.05	1.1e-05	9.0	-5.3	1.5e-07	0.08	0.91	0.00	TRUE
7	The Cancer Genome Atlas	Breast Invasive Carcinoma	NMBR	0.03	0.03	blup	46	0.02	3.6e-05	8.7	-9.6	6.7e-22	0.13	0.84	0.08	FALSE
9	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	VTA1	0.03	0.02	blup	66	0.02	1.7e-03	10.2	-9.5	3.1e-21	0.08	0.22	0.11	FALSE
13	The Cancer Genome Atlas	Thyroid Carcinoma	VTA1	0.03	0.04	enet	3	0.01	1.2e-02	8.1	-7.7	1.3e-14	0.07	0.19	0.08	FALSE
6	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	GPR126	0.06	0.00	blup	69	0.01	4.6e-02	-2.7	-7.5	4.5e-14	0.42	0.02	0.07	FALSE
10	The Cancer Genome Atlas	Brain Lower Grade Glioma	NMBR	0.07	0.05	blup	46	0.05	1.4e-06	9.0	-7.0	3.3e-12	0.10	0.98	0.00	FALSE