TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Standing height
:
←
→
chr1:52,498,112-54,432,522
Best TWAS P=1.42e-09 · Best GWAS P=2.23e-13 conditioned to 1.18e-07
52.5M
53M
53.5M
54M
54.5M
0
5
10
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
3
The Cancer Genome Atlas
Kidney Renal Papillary Cell Carcinoma
GLIS1
0.10
0.05
enet
9
0.04
2.2e-03
6.8
6.0
1.4e-09
0.50
0.08
0.67
TRUE
4
The Cancer Genome Atlas
Testicular Germ Cell Tumors
PODN
0.22
0.01
blup
94
0.06
3.3e-03
1.7
-5.8
7.5e-09
-0.01
0.00
0.09
TRUE
1
GTEx
Cells Transformed fibroblasts
ZYG11B
0.38
0.02
enet
52
0.20
1.2e-14
3.0
5.3
1.0e-07
-0.07
0.14
0.38
TRUE
2
GTEx
Spleen
ECHDC2
0.43
0.01
enet
8
0.00
4.1e-01
-4.2
-5.2
1.6e-07
0.09
0.04
0.09
FALSE