Best TWAS P=1.42e-09 · Best GWAS P=2.23e-13 conditioned to 1.18e-07
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Cells Transformed fibroblasts | ZYG11B | 0.38 | 0.02 | enet | 52 | 0.20 | 1.2e-14 | 3.0 | 5.3 | 1.0e-07 | -0.07 | 0.14 | 0.38 | TRUE |
| 2 | GTEx | Spleen | ECHDC2 | 0.43 | 0.01 | enet | 8 | 0.00 | 4.1e-01 | -4.2 | -5.2 | 1.6e-07 | 0.09 | 0.04 | 0.09 | FALSE |
| 3 | The Cancer Genome Atlas | Kidney Renal Papillary Cell Carcinoma | GLIS1 | 0.10 | 0.05 | enet | 9 | 0.04 | 2.2e-03 | 6.8 | 6.0 | 1.4e-09 | 0.50 | 0.08 | 0.67 | TRUE |
| 4 | The Cancer Genome Atlas | Testicular Germ Cell Tumors | PODN | 0.22 | 0.01 | blup | 94 | 0.06 | 3.3e-03 | 1.7 | -5.8 | 7.5e-09 | -0.01 | 0.00 | 0.09 | TRUE |