Best TWAS P=2.5e-17 · Best GWAS P=1.39e-26 conditioned to 2e-11
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | GLCCI1 | 0.20 | 0.10 | enet | 44 | 0.15 | 9.5e-18 | -5.4 | -7.4 | 1.0e-13 | 0.76 | 0.01 | 0.99 | FALSE |
| 2 | GTEx | Colon Transverse | RP5-1159O4.1 | 0.21 | 0.03 | enet | 22 | 0.04 | 6.6e-03 | -10.4 | -7.3 | 2.4e-13 | 0.71 | 0.01 | 0.95 | FALSE |
| 3 | ROSMAP | Brain Pre-frontal Cortex | GLCCI1 | 0.19 | 0.15 | enet | 19 | 0.20 | 1.8e-25 | -5.9 | -8.5 | 2.5e-17 | 0.68 | 0.76 | 0.24 | TRUE |
| 4 | ROSMAP | Brain Pre-frontal Cortex | AC006042.8 | 0.24 | 0.07 | lasso | 4 | 0.17 | 3.1e-21 | -10.3 | 6.9 | 4.4e-12 | -0.79 | 0.03 | 0.97 | FALSE |