Best TWAS P=8.4e-09 · Best GWAS P=1.46e-24 conditioned to 1.47e-20
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Lung | GIPC2 | 0.15 | 0.09 | enet | 17 | 0.12 | 2.5e-09 | -5.4 | 5.8 | 8.4e-09 | 0.19 | 1.00 | 0.00 | TRUE |
| 2 | GTEx | Pancreas | GIPC2 | 0.41 | 0.13 | enet | 29 | 0.14 | 1.1e-06 | -4.1 | 5.2 | 1.9e-07 | 0.31 | 0.65 | 0.10 | FALSE |
| 3 | The Cancer Genome Atlas | Colon Adenocarcinoma | GIPC2 | 0.04 | 0.01 | blup | 65 | 0.00 | 2.5e-01 | -4.3 | 5.6 | 2.7e-08 | 0.28 | 0.07 | 0.06 | FALSE |
| 4 | The Cancer Genome Atlas | Lung Adenocarcinoma | DNAJB4 | 0.04 | 0.04 | lasso | 2 | 0.04 | 1.2e-05 | 5.7 | -5.7 | 1.2e-08 | -0.45 | 0.00 | 0.99 | FALSE |
| 5 | The Cancer Genome Atlas | Thyroid Carcinoma | GIPC2 | 0.07 | 0.05 | blup | 64 | 0.06 | 1.5e-06 | -5.5 | 5.8 | 8.8e-09 | 0.28 | 0.67 | 0.02 | FALSE |