Best TWAS P=1.27e-10 · Best GWAS P=2.87e-12 conditioned to 9.15e-08
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | ZNHIT6 | 0.05 | 0.01 | bslmm | 552 | 0.01 | 1.9e-02 | 6.2 | -5.5 | 4.3e-08 | 0.62 | 0.04 | 0.85 | FALSE |
| 2 | ROSMAP | Brain Pre-frontal Cortex | ZNHIT6 | 0.11 | 0.12 | enet | 15 | 0.14 | 1.5e-17 | 6.3 | -5.4 | 6.0e-08 | 0.69 | 0.23 | 0.77 | FALSE |
| 3 | YFS | Blood | ODF2L | 0.04 | 0.04 | enet | 18 | 0.04 | 1.8e-12 | 5.9 | -6.4 | 1.3e-10 | 0.16 | 0.14 | 0.86 | TRUE |
| 4 | The Cancer Genome Atlas | Glioblastoma Multiforme | COL24A1 | 0.29 | 0.00 | blup | 264 | 0.06 | 5.5e-03 | 1.4 | -6.2 | 5.4e-10 | 0.11 | 0.06 | 0.05 | TRUE |