Best TWAS P=1.52e-20 · Best GWAS P=2.88e-18 conditioned to 0.000749
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | NTR | Blood | ZHX2 | 0.21 | 0.20 | lasso | 4 | 0.20 | 6.8e-63 | -8.4 | 9.3 | 1.5e-20 | 0.67 | 0.03 | 0.97 | TRUE |
2 | YFS | Blood | ZHX2 | 0.31 | 0.22 | enet | 30 | 0.25 | 1.1e-82 | -8.4 | -8.7 | 2.9e-18 | -0.60 | 0.03 | 0.97 | FALSE |